Agreement between Duke Activity Status Index and Modified Veterans Specific Activity Questionnaire in Healthy Individuals: A Cross-sectional Study

Aim. We defined the prevalence of back pain in children and adolescents aged 917 years with spinal deformities. Material and methods. The cross-sectional study included 230 students with different spinal deformities aged 917 years. The prevalence of back pain, intensity, location, and situations in which it occurred were assessed via questionnaire. Results. Among 230 respondents, 186 (80.9%) admitted that they had experienced back pain (mainly in the lumbar spine) at various frequencies within the year preceding the study. Mild pain was prevalent (71% of respondents). Girls experienced back pain significantly more frequently than boys. Conclusions. Back pain in children and adolescents requires clinical and instrumental examination, including X-ray. Back pain is a frequent phenomenon in children with different spinal deformities. Тhe incidence of pain in children and adolescents with spinal deformities in our study is statistically higher than that of healthy individuals of the same age group.

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Width and thickness of the gingiva in periodontally healthy individuals in a central Indian population: a cross-sectional study

Clinical Oral Investigations ◽

10.1007/s00784-021-04053-w ◽

2021 ◽

Author(s):

Pradeep S. Anand ◽

Abhinav Bansal ◽

Balaji R. Shenoi ◽

Kavitha P. Kamath ◽

Namitha P. Kamath ◽

...

Keyword(s):

Indian Population ◽

Cross Sectional Study ◽

Healthy Individuals ◽

Sectional Study ◽

Cross Sectional

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No QTc Prolongation in Girls and Women with Turner Syndrome

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/clinem/dgaa552 ◽

2020 ◽

Vol 105 (11) ◽

Author(s):

Iris D Noordman ◽

Anthonie L Duijnhouwer ◽

Misty Coert ◽

Melanie Bos ◽

Marlies Kempers ◽

...

Keyword(s):

Turner Syndrome ◽

Age Groups ◽

Cross Sectional Study ◽

Qtc Interval ◽

Healthy Individuals ◽

Sectional Study ◽

Qtc Prolongation ◽

Genetic Condition ◽

Cross Sectional ◽

Qt Intervals

Abstract Context Turner syndrome (TS) is a genetic condition that is reported to be associated with a prolonged rate-corrected QT (QTc) interval. Objectives To evaluate the prevalence of QTc prolongation in patients with TS, to compare their QTc intervals with healthy controls, and to investigate whether QTc prolongation is associated with a monosomy 45,X karyotype. Method Girls (n = 101) and women (n = 251) with TS visiting our center from 2004–2018 were included in this cross-sectional study. QT intervals of 12-leaded electrocardiograms were measured manually, using Bazett’s and Hodges formulas to correct for heart rate. A QTc interval of >450 ms for girls and >460 ms for women was considered prolonged. Corrected QT (QTc) intervals of patients with TS were compared to the QTc intervals of healthy girls and women from the same age groups derived from the literature. Results In total, 5% of the population with TS had a prolonged QTc interval using Bazett’s formula and 0% using Hodges formula. Mean QTc intervals of these patients were not prolonged compared with the QTc interval of healthy individuals from the literature. Girls showed shorter mean QTc intervals compared with women. We found no association between monosomy 45,X and prolongation of the QTc interval. Conclusions This study shows that the QTc interval in girls and women with TS is not prolonged compared with the general population derived from the literature, using both Bazett’s and Hodges formulas. Furthermore, girls show shorter QTc intervals compared with women, and a monosomy 45,X karyotype is not associated with QTc prolongation.

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Health consequences of thick forest fire smoke to healthy residents in Riau, Indonesia: a cross-sectional study

Medical Journal of Indonesia ◽

10.13181/mji.oa.204321 ◽

2020 ◽

Vol 29 (1) ◽

pp. 58-63 ◽

Cited By ~ 1

Author(s):

Jamal Zaini ◽

Agus Dwi Susanto ◽

Erlang Samoedro ◽

Vonni Christiana Bionika ◽

Budhi Antariksa

Keyword(s):

Lung Function ◽

Forest Fire ◽

Respiratory Symptoms ◽

Cross Sectional Study ◽

Healthy Individuals ◽

Sectional Study ◽

Cross Sectional ◽

Fire Disaster ◽

Fire Smoke ◽

Forest Fire Disaster

BACKGROUND Indonesia forest fire in 2015 emitted a huge amount of pollutants into the air. This study was aimed to assess the health consequences of forest fire smoke in healthy residents in Riau during forest fire disaster in 2015. METHODS This cross-sectional study was performed in healthy residents who lived in Pekanbaru, Riau Province, Sumatera, for at least 6 months during forest fire disaster in 2015, and data were taken in October 2015. Questionnaires consisting of respiratory and non-respiratory symptoms were collected. Lung function was assessed by spirometry (MIR II Spirolab™ spirometer, Medical International Research, Italy) and exhaled carbon monoxide (CO) was assessed using piCO+ Smokerlyzer®. Heart rate at rest and oxygen saturation in the room air were measured using Onyx 9591 Pulse Oximeter®. RESULTS A total of 89 subjects were mostly female (75.3%), housewife (37.7%), nonsmoker (86.5%) with mean age of 38.9 years old. The non-respiratory and respiratory symptoms were reported in 84.7% and 71.4% subjects, respectively. Lung function was impaired in 72.6% subjects, mostly with mild obstruction and mild restriction. Exhaled CO was highly detected over normal values (mean [standard deviation] = 32.6 [9.97] ppm) with predicted carboxyhemoglobin (COHb) of 5.74 (1.56). CONCLUSIONS Forest fire smoke exposure increased the respiratory and nonrespiratory symptoms among healthy individuals, which showed impairment in lung function, exhaled CO, and predicted COHb. Long term health effects on healthy individuals exposed to forest fire smoke warrant further evaluation.

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Conjunctival bacterial flora in diabetic patients

Ibrahim Medical College Journal ◽

10.3329/imcj.v7i1.17698 ◽

2014 ◽

Vol 7 (1) ◽

pp. 5-8 ◽

Cited By ~ 1

Author(s):

Najmun Nahar ◽

Shaheda Anwar ◽

Md Ruhul Amin Miah

Keyword(s):

Staphylococcus Epidermidis ◽

Bacterial Flora ◽

Positive Culture ◽

Study Groups ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Healthy Individuals ◽

Sectional Study ◽

Cross Sectional ◽

Conjunctival Flora

Conjunctival flora refers to population of microorganisms that dwell within the eyes of healthy individuals and is important in maintaining a healthy ocular surface and normal conjunctival function. Conjunctival flora may be altered by a variety of factors that include age, immunosuppression and geography. Immune function is compromised in diabetes mellitus. The aim of the present study was to see the pattern of conjunctival bacterial flora in diabetic and non-diabetic patients. This cross sectional study was carried out in BSMMU during the period of January 2011 to December 2011. Total 500 conjunctival swabs were collected from both eyes of 50 diabetic patients attending OPD of Endocrinology Department of BSMMU and 200 non-diabetic individuals. Significant number of culture was positive in diabetic patients (64.0%) compared to that of non-diabetic individuals (38.0%). Staphylococcus epidermidis was predominant in both study groups (diabetic vs non-diabetic: 41.3% vs 65.26%). Staphylococcus aureus (15.22%), Escherichia coli (6.52%) and Enterobacter (8.33%) were isolated in diabetic patients. Rate of positive culture in both and single eyes were higher in diabetic (28%, 36.0%) than that of non-diabetic individuals (9.5%, 28.5%). DOI: http://dx.doi.org/10.3329/imcj.v7i1.17698 Ibrahim Med. Coll. J. 2013; 7(1): 5-8

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Analysis of heparanase isoforms and cathepsin B in the plasma of patients with gastrointestinal carcinomas: analytical cross-sectional study

Sao Paulo Medical Journal ◽

10.1590/1516-3180.2013.7080003 ◽

2015 ◽

Vol 133 (1) ◽

pp. 28-35 ◽

Cited By ~ 2

Author(s):

Carina Mucciolo Melo ◽

Clarice Silvia Taemi Origassa ◽

Thérèse Rachell Theodoro ◽

Leandro Luongo Matos ◽

Thaís Aguilar Miranda ◽

...

Keyword(s):

Cathepsin B ◽

Cross Sectional Study ◽

Control Group ◽

Plasma Samples ◽

Healthy Individuals ◽

Sectional Study ◽

Gastrointestinal Carcinoma ◽

Control Group Design ◽

Cross Sectional ◽

Gastrointestinal Carcinomas

CONTEXT AND OBJECTIVE: Heparanase-1 degrades heparan sulfate and has been correlated with tumor progression. Although the isoform heparanase-2 has no catalytic activity, it seems to be important for modulating heparanase-1 activity. Cathepsin B is a proteinase involved in tumor metastasis. The aim of this study was to analyze heparanase isoform expression and cathepsin B activity in plasma samples from patients with gastrointestinal carcinomas, compared with healthy individuals (control group). DESIGN AND SETTING: This was an analytical cross-sectional study. Peripheral blood samples were collected at a Brazilian public hospital, from 21 patients with histopathological diagnoses of gastrointestinal carcinomas and from 43 healthy individuals. The analyses were performed in two Brazilian medical schools. METHODS: Heparanase isoforms were identified and quantified in plasma samples by means of Western blot. The enzymatic activities of heparanase-1 and cathepsin B were also measured. RESULTS: The results demonstrated that the expression of both heparanase isoforms was significantly greater in plasma samples from gastrointestinal carcinoma patients, compared with the control group. Logistic regression analysis showed that increased heparanase-1 and heparanase-2 expression was exclusively dependent on the tumor. There was a significant increase in heparanase-1 and cathepsin B activity in the patients' plasma. CONCLUSION: Overexpression of heparanase-1 and heparanase-2, along with increased heparanase-1 and cathepsin B activity in plasma, is associated with the diagnosis of gastrointestinal carcinoma. These findings provide support for using non-invasive assays (plasma samples) as an auxiliary method for diagnosing gastrointestinal tumors.

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Maximum Power During Vertical Jump and Isometric Knee Extension Torque Alter Mobility Performance: A Cross-Sectional Study of Healthy Individuals

PM&R ◽

10.1016/j.pmrj.2015.04.012 ◽

2015 ◽

Vol 8 (1) ◽

pp. 19-27 ◽

Cited By ~ 4

Author(s):

Atsuhiro Tsubaki ◽

Masayoshi Kubo ◽

Ryosaku Kobayashi ◽

Hirofumi Jigami ◽

Kazuhiro Sugawara ◽

...

Keyword(s):

Vertical Jump ◽

Knee Extension ◽

Cross Sectional Study ◽

Maximum Power ◽

Healthy Individuals ◽

Sectional Study ◽

Cross Sectional ◽

Mobility Performance ◽

Isometric Knee Extension

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Comparison of Plasma Neurosteroid and Prolactin Levels in Patients with Schizophrenia and Healthy Individuals

Scientifica ◽

10.1155/2016/3108689 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Forough Riahi ◽

Maryam Izadi-mazidi ◽

Ali Ghaffari ◽

Elham Yousefi ◽

Shahram Khademvatan

Keyword(s):

Analysis Of Variance ◽

Serum Testosterone ◽

Cross Sectional Study ◽

Serum Testosterone Level ◽

First Episode ◽

Healthy Individuals ◽

Sectional Study ◽

Cross Sectional ◽

Hormone Levels ◽

First Episode Schizophrenia

Background.The present study aimed to compare plasma levels of cortisol, testosterone, dehydroepiandrosterone (DHEA), and prolactin in patients with schizophrenia and healthy individuals.Method.A total of 100 patients with schizophrenia disorder (69 men and 31 women) and 190 healthy individuals (94 men and 96 women) participated in this cross-sectional study. They were tested for hormone levels and completed demographic questionnaires. Data were analyzed using multivariate analysis of variance (MANOVA) and one-way analysis of variance.Results.Serum testosterone level was significantly higher in men with schizophrenia than in healthy men. Women with schizophrenia had a significantly higher level of testosterone and lower level of prolactin compared to healthy women. There were no significant differences in hormone levels across various subtypes of schizophrenia. No significant differences also were observed in hormones levels in patients with first-episode schizophrenia disorder compared to those in patients with recurrent episodes.Conclusion.This study indicated that abnormal testosterone and prolactin levels might be associated with pathophysiology of schizophrenia disorder.

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The relationship between the TSH values and the Tpeak – Tend interval duration in hypothyroid patients receiving Levothyroxine treatment

Romanian Journal of Internal Medicine ◽

10.2478/rjim-2018-0042 ◽

2019 ◽

Vol 57 (2) ◽

pp. 175-180

Author(s):

Hüseyin Avni Findikli ◽

Ayşe Şahin Tutak ◽

Hakan Aydin

Keyword(s):

Hormone Level ◽

Cross Sectional Study ◽

Healthy Individuals ◽

Sectional Study ◽

Control Groups ◽

Cross Sectional ◽

And Control ◽

The Relationship ◽

Hypothyroid Patients ◽

Levothyroxine Treatment

Abstract Introduction. Changes in thyroid hormone level can affect the cardiovascular system. The aim of this study was to show how the Tpeak -Tend (Tpe) interval, which is a new marker of ventricular arrythmia, is affected in patients who have become euthyroid following Levothyroxine treatment for hypothyroidism, as this has not been examined previously in literature. Materials and Methods. This, cross-sectional study included a total of 119 females aged 18-45 years, separated into 3 groups as hypothyroid, euthyroid and control groups. For evaluation of the QTc and Tpe intervals, examination on precordial V5 lead was made of all the ECGs taken routinely on presentation of the patients. Results. The Tpe and QTc intervals of the hypothyroid group were determined to be significantly prolonged compared to those of the euthyroid and control groups (p < 0.001) and the values of the euthyroid and control groups were similar. A positive correlation was determined between TSH levels and Tpe and QTc intervals. Tpe interval AUC = 0.801 (%95 CI: 0.719 – 0.884) was higher than that of QTc AUC = 0.689 (%95 CI: 0.591 – 0.786). Conclusions. The Tpe duration was evaluated in respect of the risk of arrythmia in hypothyroid patients. In patients who had become euthyroid, the Tpe interval was found to be similar to that of healthy individuals and was more predictive than QTc. In the light of these findings it can be recommended that measurement of the Tpe interval should be preferred to QTc as a marker of the arrythmogenic effect in hypothyroid patients.

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Estimación de la tasa de filtración glomerular en personas con y sin síndrome metabólico

Revista Facultad de Ciencias de la Salud UDES ◽

10.20320/rfcsudes.v3i1.102 ◽

2016 ◽

Vol 3 (1) ◽

pp. 22

Author(s):

María E Lizardo ◽

María del Pilar Navarro ◽

Marqjuly Camacho ◽

Melvimar Alejandra Magallanes-Hernández ◽

Rubsy Gabriela Pacheco-Gutiérrez ◽

...

Keyword(s):

Abdominal Obesity ◽

Cross Sectional Study ◽

Strongly Correlated ◽

Healthy Individuals ◽

Sectional Study ◽

Cross Sectional ◽

Glomerular Function ◽

Síndrome Metabólico ◽

System Risk ◽

Apparently Healthy

Introduction: Metabolic syndrome (MS) is an independent risk factor, which affects the development of chronic kidney disease, so the glomerular filtration rate (GFR) as an indicator of glomerular function in patients with and without MS who attended the outpatient clinic “los Grillitos, sector Caña de Azucar”. Materials and Methods: A comparative, correlational, cross-sectional study was conducted in a non-probability sample of convenience consisting of 60 patients with MS diagnosed according to the criteria Panel ATP III, and 60 apparently healthy individuals, whom the GFR was determined by the Cockcroft-Gault as well as clinical and biochemical parameters for the diagnosis of MS. Results: Out of the total patients evaluated, 37 (30.7%) showed alterations that put them in grades G2 and G3 system risk stratification of CKD, of these 18 and 19 corresponded to patients with and without MS respectively. Glomerular Hyperfiltration (> 120 mil / min) it was found in both groups 28 (46.7%) and 24 (40%) cases of patients with and without MS respectively. The glomerular function was strongly correlated with abdominal obesity and high levels of stress arterial. As for the number of criteria and its relationship to the level of kidney damage present, not a firm to increase the latter with respect to the first (p=0.385) trend was observed. Conclusion: The change in the glomerular function is not directly related to the MS but with its components, specifically abdominal obesity and hypertension.

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