CASE REPORT: COMPLICATION AT BOTH RECEIVING AND DONOR SITES  IN FACIAL AUTOLOGOUS FAT TRANSFER

Autologous fat grafting is a technique that has been used for a long time in the field of plastic surgery. Besides many advantages, the complications, which can range from mild such as hematoma, infection, calcification, necrosis... even death is a big problem. The article presents a case of using autologous fat taken from the abdomen to graft onto the facial area with complications of severe infection in both the receiving and donor sites, causing necrosis of fat and skin in both areas. The treatment takes a long time with different procedures, but the consequences for the patient are still very serious both in terms of aesthetics and function. The objective of this study was to evaluate the safety and efficacy of fat grafting to the facial region for the reconstruction and aesthetic enhancement of facial contour.

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Treatment of “En Coupe De Sabre “ Linear Scleroderma. Soft Tissue Augmentation and Regeneration by Autologous Fat Transfer

American Journal of Surgical Research and Reviews ◽

10.28933/ajsrr-2021-07-0103 ◽

2021 ◽

pp. 30

Author(s):

◽

Keyword(s):

Stem Cells ◽

Soft Tissue ◽

Fat Grafting ◽

Soft Tissue Augmentation ◽

Congenital Deformity ◽

Autologous Fat Grafting ◽

Fat Transfer ◽

Autologous Fat ◽

Autologous Fat Transfer ◽

Linear Scleroderma

Aim: Frontal linear scleroderma, also known as ‘‘en coup de sabre,’’ is a congenital deformity characterized by atrophy and furrowing of the skin of the front parietal area above the level of the eyebrows. In most cases it occurs as a single paramedian line that may be associated with hypoplasia of underlying structures and facial hemiatrophy. In case of a wide lesion many reconstructive strategies have been proposed. The modern approach is aimed at augmentation of the tissue deficiency by using lipostructure and tissue regeneration. Autologous fat transfer (AFT) seems to be an effective strategy to restore the normal volume and contour of the face while providing a source of adipose-derived stem cells (ADSCs) with a multilineage differentiation potential. Methods: In this report, we present a rare case of linear scleroderma en coupe de sabre which was successfully managed with three stages of autologous fat grafting. Conclusion: The proposed uses for ADSCs in tissue repair and regeneration are quite impressive. Recent works on ADSCs would suggest that adult cells may prove to be an equally powerful regenerative tool in treating congenital and acquired maxillofacial disorders. More importantly, physicians, researchers and international associations need to cooperate in informing clinicians about what practices are based on evidence and to encourage support of additional research. There is increasing interest in a possible therapeutic effect of ADSCs from processed lipoaspirate for a wide spectrum of clinical applications in the facial and craniofacial area. AFT can be used in any facial area where soft tissue is lacking or where there is scarring, producing natural and long-lasting results. Mesenchymal stem cells represent a great tool in regenerative medicine. However, more definitive studies are needed to answer specific questions regarding the best technique to be used and the role of ADSCs. Autologous fat grafting provides a safe and easy approach for the treatment of linear scleroderma en coup de sabre, long-term clinically satisfactory results can be obtained.

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Autologous Fat Grafting in the Treatment of Facial Scleroderma

Dermatology Research and Practice ◽

10.1155/2018/6568016 ◽

2018 ◽

Vol 2018 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Mehdi Gheisari ◽

Arman Ahmadzadeh ◽

Nilofar Nobari ◽

Behzad Iranmanesh ◽

Nikoo Mozafari

Keyword(s):

Systemic Sclerosis ◽

Treatment Options ◽

Mouth Opening ◽

Fat Grafting ◽

Systemic Autoimmune Disease ◽

P Value ◽

Fat Injection ◽

Autologous Fat Grafting ◽

Autologous Fat ◽

Autologous Fat Transfer

Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by progressive cutaneous and internal organ fibrosis. Orofacial manifestations of systemic sclerosis are extremely disabling and treatment options are limited. In this study, we aimed to assess the safety and efficacy of autologous fat grafting in the face of patients with systemic sclerosis. We enrolled 16 SSc patients suffering from facial sclerosis and limited mouth opening capacity. Autologous fat injection ranging from 15 to 40 ml was administered per patient, based on their face morphology. The patients were evaluated at baseline and 3 months after fat injection. Evaluations included mouth opening capacity, mouth handicap in systemic sclerosis (MHISS), Rodnan skin sclerosis score, skin biophysical properties using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT), volumizing and aesthetic effects based on pre- and posttreatment photographs, possible side effects, and global patient satisfaction. Clinical assessment showed autologous fat transfer significantly improved mouth opening capacity and the MHISS and Rodnan score of patients with facial scleroderma (p value <.001). The aesthetic and/or functional results of fat injection were satisfying to about 80% of the patients. The changes in CRRT values were not significant. Our findings support the possible therapeutic role of autologous fat grafting in improving facial scleroderma both in aesthetic and in functional aspects. This trial is registered with IRCT20180209038677N1.

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Letter: Autologous Fat Grafting and Platelet-Rich Plasma for Treatment of Facial Contour Defects

Dermatologic Surgery ◽

10.1111/j.1524-4725.2012.02515.x ◽

2012 ◽

Vol 38 (9) ◽

pp. 1572-1574 ◽

Cited By ~ 9

Author(s):

Kui Young Park ◽

In Su Kim ◽

Beom Joon Kim ◽

Myeung Nam Kim

Keyword(s):

Platelet Rich Plasma ◽

Fat Grafting ◽

Autologous Fat Grafting ◽

Autologous Fat ◽

Facial Contour ◽

Contour Defects

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Protocol for a Systematic Review of Outcome Measurement Tools for Autologous fat Grafting of the Facial Region

10.21203/rs.3.rs-99448/v1 ◽

2020 ◽

Author(s):

Sophie Speiser ◽

Aurora Almadori ◽

Benjamin J. Langridge ◽

Peter EM Butler

Keyword(s):

Systematic Review ◽

Reconstructive Surgery ◽

Literature Search ◽

Outcome Measurement ◽

Fat Grafting ◽

Autologous Fat Grafting ◽

Autologous Fat ◽

Plastic And Reconstructive Surgery ◽

Facial Region ◽

Measurement Tools

Abstract BackgroundAutologous fat grafting has become an established therapeutic entity in several regions of the body. Especially in the facial region, AFG has been widely applied in the field of plastic and reconstructive surgery. Indications include reconstructive purposes such as primary genetic disorders in maxillofacial development, or secondary asymmetries following primary reconstructive surgery. In addition, AFG has found several applications in the field of aesthetic surgery, such as skin rejuvenation. In addition to conventional AFG, recently several alternative strategies of grafting have been developed. Examples for these are transplantation of a graft including adipose derived stem cells (ADSC’s), cell-assisted lipofilling (CAL), and grafting with stromal vascular fraction (SVF). Until today, there is no common consensus on how to measure a successful outcome of autologous graft transplantation in the facial region. This systematic review aims to critically evaluate the current available outcome measurement methods, and compare them with regards to accuracy, cost-effectiveness, safety and validation in the clinical setting. The quality of evidence of included publications will be assessed using the GRADE strategy.MethodsA comprehensive, structured literature search of published articles will be conducted. This is designed by authors and performed in adherence to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA-P). The literature search will be performed using the electronic databases MEDLINE (PubMed), EMBASE and Cochrane Library, including publications from inception to May 2020. Two independent authors will conduct the search, screen the articles, and complete data collection. The main outcome will be which methods are currently used to determine a successful fat grafting procedure in the face. We propose to review the current methods used to establish their overall performance in several domains. In addition, patients measured via the 3D volumetric photography method will be further analysed with regards to accuracy of the camera and retention of fat per method and ml injected.Discussion Autologous fat grafting in the facial region has gained significant attention in the field of plastic and reconstructive surgery in the past decades. In light of the growing public interest in this topic, a systematic review of the outcome measurement tools is of essence. We will critically evaluate all approaches currently in practice and give a recommendation regarding several aspects of use. A common approach to measurement and reporting of results fosters an environment of high-standard healthcare delivery and promotes future research and informed clinical practice. In addition, we will further analyse the outcomes of different grafting methods using 3D volumetric photography as measurement tool. PROSPERO registration number: CRD42020213407

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