scholarly journals The Effects of Locally Administered Morphine Over the Dura on Postoperative Morphine Consumption and Pain After Lumbar Disc Surgery: A Prospective, Randomised, Double-Blind and Placebo-Controlled Study

2019 ◽  
Vol 47 (4) ◽  
pp. 301-306
Author(s):  
Oguzhan Kayhan ◽  
◽  
Eren Fatma Akcil ◽  
Ozlem Korkmaz Dilmen ◽  
Yusuf Tunali ◽  
...  
Keyword(s):  
Lumbar Disc ◽  
Morphine Consumption ◽  
Lumbar Disc Surgery ◽  
Controlled Study ◽  
Double Blind ◽  
Disc Surgery ◽  
Postoperative Morphine

Intrathecal steroids to reduce pain after lumbar disc surgery: a double-blind, placebo-controlled prospective study

Pain ◽  
1995 ◽  
Vol 62 (3) ◽  
pp. 357-361 ◽  
Author(s):  
Johann J. Langmayr ◽  
Alois A. Obwegeser ◽  
Andreas B. Schwarz ◽  
Ilse Laimer ◽  
Hanno Ulmer ◽  
...  
Keyword(s):  
Prospective Study ◽  
Lumbar Disc ◽  
Lumbar Disc Surgery ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Disc Surgery

Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery

2010 ◽  
Vol 27 (5) ◽  
pp. 428-432 ◽  
Author(s):  
Ozlem Korkmaz Dilmen ◽  
Yusuf Tunali ◽  
Ozlem S Cakmakkaya ◽  
Ercument Yentur ◽  
Ayse C Tutuncu ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Lumbar Disc ◽  
Morphine Consumption ◽  
Lumbar Disc Surgery ◽  
Disc Surgery ◽  
Intravenous Paracetamol

Effect of Celecoxib and Dexamethasone on Postoperative Pain after Lumbar Disc Surgery

Neurosurgery ◽  
2003 ◽  
Vol 53 (2) ◽  
pp. 331-337 ◽  
Author(s):  
Matthias Karst ◽  
Tanja Kegel ◽  
Anne Lukas ◽  
Wolf Lüdemann ◽  
Samii Hussein ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Lumbar Disc ◽  
Lumbar Disc Surgery ◽  
Double Blind Study ◽  
Double Blind ◽  
Wound Area ◽  
Pain Scores ◽  
Disc Surgery ◽  
Pain At Rest ◽  
To Receive

Abstract OBJECTIVE This study was designed to assess the efficacy of perioperative administration of celecoxib (Celebrex; Pharmacia GmbH, Erlangen, Germany) in reducing pain and opioid requirements after single-level lumbar microdiscectomy. METHODS We studied 34 patients (mean age, 44.26 yr; standard deviation [SD], 13.09 yr) allocated randomly to receive celecoxib 200 mg twice a day for 72 hours starting on the evening before surgery or placebo capsules in a double-blind study. Fourteen patients received 20 to 80 mg dexamethasone intravenously during surgery (mean, 40 mg; SD, 19.22 mg) because of visible signs of compression of the affected nerve root. After lumbar disc surgery, patients were monitored for visual analog scores for pain at rest and on movement, patient-controlled analgesia (PCA) piritramide requirements, and von Frey thresholds in the wound area. RESULTS Pain scores decreased and wound von Frey thresholds increased continuously until discharge, with no intergroup differences. Mean 24-hour PCA piritramide requirements were 22.63 mg (SD, 23.72 mg) and 26.14 mg (SD, 22.57 mg) in the celecoxib and placebo groups, respectively (P = not significant). However, patients with intraoperative dexamethasone (n = 14) required only 10.29 mg (SD, 8.55 mg) 24-hour PCA piritramide, in contrast to the 34.25 mg (SD, 24.69 mg) needed in those who did not receive intraoperative dexamethasone (P = 0.001). In addition, 24 hours after the operation, pain scores on movement were significantly lower in the dexamethasone subgroup (P = 0.003). CONCLUSION Celecoxib has no effect on postoperative pain scores and PCA piritramide requirements. The intraoperative use of 20 to 80 mg dexamethasone is able to significantly decrease postoperative piritramide consumption and pain scores on the first day after surgery.

Bilateral mandibular block improves pain relief and morphine consumption in mandibular osteotomies: a prospective, randomized, double-blind, placebo-controlled clinical trial

2021 ◽  
Vol 46 (4) ◽  
pp. 322-327
Author(s):  
Marina Bertuit ◽  
Francesca Rapido ◽  
Habib Ly ◽  
Charlotte Vannucci ◽  
Jérôme Ridolfo ◽  
...  
Keyword(s):  
Postoperative Analgesia ◽  
Severe Pain ◽  
Postoperative Nausea And Vomiting ◽  
Sensory Innervation ◽  
Morphine Consumption ◽  
Controlled Study ◽  
Controlled Clinical Trial ◽  
Block Group ◽  
Double Blind ◽  
Double Blind Placebo

BackgroundThe sensory innervation of the lower jaw mainly depends on the third root of the trigeminal nerve, the mandibular nerve (V3). The aim of this single-center, prospective, randomized, double-blind, placebo-controlled study was to evaluate the effectiveness of bilateral V3 block for postoperative analgesia management in mandibular osteotomies.Methods107 patients undergoing mandibular surgery (75 scheduled osteotomies and 32 mandible fractures) were randomized in two groups. A bilateral V3 block was performed in each group, either with ropivacaine 0.75% (block group, n=50) or with a placebo (placebo group, n=57). A postoperative multimodal analgesia was equally provided to both groups. The primary outcome was the cumulative morphine consumption at 24 hours. Secondary outcomes were the occurrence of severe pain and the incidence of postoperative nausea and vomiting (PONV) in the first 24 hours. Data were analyzed on an intention-to-treat basis.ResultsThe cumulative morphine consumption at 24 hours was significantly lower in the block group (median 8.0 mg (IQR 2.0–21.3) vs 12.0 mg (IQR 8.0–22.0), p=0.03), as well as the incidence of severe pain during the 24 hours of follow-up (4.0% vs 22.8%, p<0.01). The mandibular block had no impact on the incidence of PONV.ConclusionBilateral V3 block for mandibular osteotomies is an effective opioid-sparing procedure. It provided better postoperative analgesia in the first 24 hours, and it did not affect PONV incidence.Trial registration numberNCT02618993.

scholarly journals Residual complaints following lumbar disc surgery: prognostic indicators of outcome

Pain ◽  
2005 ◽  
Vol 114 (1) ◽  
pp. 177-185 ◽  
Author(s):  
Raymond W.J.G. Ostelo ◽  
Johan W.S. Vlaeyen ◽  
Piet A. van den Brandt ◽  
Henrica C.W. de Vet
Keyword(s):  
Lumbar Disc ◽  
Lumbar Disc Surgery ◽  
Prognostic Indicators ◽  
Disc Surgery

Lumbar disc surgery in the third trimester – with the fetus in utero

2006 ◽  
Vol 15 (2) ◽  
pp. 182 ◽  
Author(s):  
A. Kathirgamanathan ◽  
A.D. Jardine ◽  
D.M. Levy ◽  
M.P. Grevitt
Keyword(s):  
Lumbar Disc ◽  
In Utero ◽  
Lumbar Disc Surgery ◽  
Third Trimester ◽  
The Third ◽  
Disc Surgery

scholarly journals Abdominal aortic injury due to lumbar disc surgery: A case report

2014 ◽  
Vol 29 (4) ◽  
pp. 192-196 ◽  
Author(s):  
Ramazan Yildiz ◽  
Muharrem Oztas ◽  
Mehmet Ali Sahin ◽  
Gokhan Yagci
Keyword(s):  
Case Report ◽  
Lumbar Disc ◽  
Aortic Injury ◽  
Lumbar Disc Surgery ◽  
Disc Surgery ◽  
Abdominal Aortic
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