Cutaneous reaction to sea urchin spines

Author(s):  
Cassidy Johnston ◽  

A 35-year-old male returned from vacation in Hawaii where he went scuba diving and snorkeling. While snorkeling, he stepped on a sea urchin and sustained injuries to the dorsal aspect of his right foot. He began to swim back to shore when he felt significant pain and began removing visible spines when he reached shore. He saw a physician in Hawaii who removed remaining spines and started a treatment regimen of cephalexin 500 mg QID. Patient followed up 2 weeks later with his home dermatologist for persistent granuloma and was given 15-day course of oral doxycycline 50 mg BID with near full recovery within 2 weeks. Even physicians practicing inland need to be aware of coastal injuries and reactions as they can mimic other common skin tumors such as keratoacanthomas.

2014 ◽  
Vol 99 (793-Suplemento I) ◽  
pp. 21-26 ◽  
Author(s):  
Salvador Arias-Santiago ◽  
María Sierra Girón-Prieto ◽  
Luisa Castellote-Caballero
Keyword(s):  

2020 ◽  
Vol 22 (4) ◽  
pp. 1900922 ◽  
Author(s):  
Christoph Lauer ◽  
Sebastian Haußmann ◽  
Patrick Schmidt ◽  
Carolin Fischer ◽  
Doreen Rapp ◽  
...  

1971 ◽  
Vol 3 (3) ◽  
pp. 235-250 ◽  
Author(s):  
Walter F. Lever
Keyword(s):  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Wybke Klatt ◽  
Susanne Wallner ◽  
Christoph Brochhausen ◽  
Judith A. Stolwijk ◽  
Stephan Schreml

Abstract The proton-sensing GPCRs (pH-GPCRs) GPR4 (GPR19), TDAG8 (GPR65, T-cell death associated gene 8), OGR1 (GPR68, ovarian cancer GPCR1), and G2A (GPR132, G2 accumulation protein) are involved in sensing and transducing changes in extracellular pH (pHe). Extracellular acidification is a central hallmark of solid cancer. pH-GPCR function has been associated with cancer cell proliferation, adhesion, migration and metastasis, as well as with modulation of the immune system. Little is known about the expression levels and role of pH-GPCRs in skin cancer. To better understand the functions of pH-GPCRs in skin cancer in vivo, we examined the expression-profiles of GPR4, TDAG8, OGR1 and G2A in four common skin tumors, i.e. squamous cell carcinoma (SCC), malignant melanoma (MM), compound nevus cell nevi (NCN), basal cell carcinoma (BCC). We performed immunohistochemistry and immunofluorescence staining on paraffin-embedded tissue samples acquired from patients suffering from SCC, MM, NCN or BCC. We show the expression of pH-GPCRs in four common skin cancers. Different expression patterns in the investigated skin cancer types indicate that the different pH-GPCRs may have distinct functions in tumor progression and serve as novel therapeutic targets.


1977 ◽  
Vol 70 (5) ◽  
pp. 640
Author(s):  
Harry L. Arnold
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document