scholarly journals An Observational Study on Idiopathic Intracranial Hypertension (IIH) in a Tertiary Care Hospital in Bangladesh

2022 ◽  
Vol 8 (1) ◽  
pp. 333-340
Author(s):  
Md. RashidoonNabi Khan

Background: Among the risk factors of cardiovascular diseases, hypertension is one of the major reason. Intracranial hypertension (IIH) is a pressure buildup around the brain. It can happen unexpectedly, as a result of a severe head injury, stroke, or brain abscess could be occurred. It could also be a chronic, long-term condition, known as IIH. It results in the signs and symptoms of a brain tumor. Which is also known as benign intracranial hypertension. Cerebrospinal fluid, or CSF, is the fluid that surrounds the spinal cord and brain. CSF can accumulate if too much fluid is produced or not enough is reabsorbed. This can induce symptoms similar to a brain tumor. Intracranial Hypertension can be classified into three categories, they are Acute, Chronic and Idiopathic. IIH is recognized when the increased intracranial pressure cannot be explained by any other underlying cause.Aim: The aim of the study was to observe idiopathic intracranial hypertension patients in a select tertiary care hospital of Bangladesh.Methods:This cross-sectional observational study was conducted at the Department of Neurosurgery, Sylhet M. A. G. Osmani Medical College Hospital, Sylhet, Bangladesh. The study duration was from January 2012 to December 2020. A total number of 47 participants had been recruited as study population.Results:Male: female ratio was 1:10.75, and 91% of the total participants were female. 40.43% of the participants were aged between 21-30 years. 46.81% were overweight and 34.04% were obese. Most common symptom was nausea, followed by visual impairment and double vision.Conclusion:The prevalence of Idiopathic Intracranial Hypertension is much higher among the female. Female and high BMI are significant risk factors of IIH. It is more prevalent among young adults, and results on various vision related symptoms.

Author(s):  
Aline Z. de Azambuja ◽  
Gustavo Wissmann Neto ◽  
Guilherme Watte ◽  
Luciana Antoniolli ◽  
Luciano Z. Goldani

Objective.Cryptococcus neoformansis a common opportunistic infection in adults with acquired immunodeficiency syndrome worldwide. However, limited data exist for HIV-infected patients in the post-HAART (highly active antiretroviral therapy) era in Brazil. The aim of this study was to describe the clinical characteristics and outcomes of cryptococcosis in a cohort of patients attending a teaching tertiary care hospital in southern Brazil after the introduction of HAART in Brazil.Patients and Methods. A retrospective study was conducted in tertiary care hospital in southern Brazil. Detailed data on risk factors, clinical manifestations, diagnosis methods, treatment, and prognosis of patients with meningeal cryptococcosis were evaluated from January 2009 to December 2016.Results. Seventy-nine cases of cryptococcal meningitis were identified. Most of the patients presented positive CSF (cerebrospinal fluid) cultures forCryptococcus neoformans(96%). The prevalence of males and females with meningeal cryptococcosis was similar. The age of the patients ranged from 5 to 67 years. The median time of hospitalization was 28 days. The most common underlying disease was HIV (82%), followed by solid transplant (10%). Fever, nausea, vomiting, headache, and altered mental status were the most common clinical manifestations. Initial opening intracranial pressures varied from 30 to 130 cm H2O. CNS imaging abnormalities include hydrocephalus and hypodensities. Widened Virchow–Robin spaces were described in only 2 patients (2.5%). Induction treatment of the majority of the patients consisted of amphotericin B and flucytosine (67%) followed by amphotericin B and fluconazole (19%). Multivariate analysis of Cox regression identified headache at presentation, mechanical ventilation, CSF glucose <20 mg/dL, and CSF cryptococcal antigen ≥1 : 1000 for independent risk factors for death. All-cause 30-day and 60-day mortalities were 19% and 24%, respectively.Conclusions. Meningeal cryptococcosis mostly caused byC. neoformanscontinues to occur predominantly in HIV-infected adults despite HAART being widely distributed in Brazil. Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Despite adequate antifungal treatment and management of intracranial hypertension in a reference tertiary care hospital, mortality was high. Identification of risk factors and additional treatment modalities, especially for intracranial hypertension, are necessary to improve care for patients with cryptococcal meningitis.


2017 ◽  
Vol 4 (7) ◽  
pp. 2326 ◽  
Author(s):  
R. D. Jaykar ◽  
A. S. Varudkar ◽  
Anirudh K. Akamanchi

Background: Ventral hernias are one of the most common problems confronting general surgeons. Incisional hernia is a common long-term complication of abdominal surgery and is estimated to occur in 3% to 13% of laparotomy incisions. Because there is no prospective cohort available to determine the natural history of untreated ventral hernias, most surgeons recommend that these hernias should be repaired when discovered. So, there was a need to study the disease with respect to the various presentations, to gauge the awareness levels of the patients coming to us and also to determine the best modality of treatment in our set-up. This study was done to know the proportion of ventral hernias occurring in both sexes, various age groups, various risk factors and complications of different types of ventral hernias, clinical presentations and their treatment. Methods: This was a prospective study done at our tertiary care hospital between August 2014 and August 2015 (12 months). A total number of 50 cases of anterior abdominal hernias excluding groin hernias, posterior abdominal wall hernia was studied. Data collection included a detailed history and a thorough clinical examination. Data was entered in the proforma, tabulated and analyzed using software package for statistical analysis (SPSS 2015).Results: Ventral hernia constituted 4% of all admissions to the surgical ward. Incisional hernia was the most common amongst the ventral hernias with an incidence of 46%. Infra umbilical midline was the most common site for herniation in 42% of cases followed by umbilical region in 32% of cases. Obesity and constipation were found to be the major predisposing risk factors. Small defects (<2cm) presented early with more complications.Conclusions: In the present study of ventral hernias, 50 cases of ventral hernias that were admitted to Department of Surgery in our tertiary care hospital. Ventral hernia constituted 4% of all admissions to the surgical ward. The male to female ratio was 1:1.9 The mean age was approximately 41 years. Incisional Hernia was strangulated umbilical hernia - intra operative the most common variety.


Author(s):  
CHINMAYI PINNA ◽  
Dharavath Vinay Naik Dharavath Vinay Naik ◽  
Naresh Podugu Naresh Podugu ◽  
Shaik.Mohammed Shaabaaz Shaik.Mohammed Shaabaaz ◽  
Okeke Chukwugoziem Bright Okeke Chukwugoziem Bright

Background: coronary artery disease is one of the most common types of cardiovascular disorder and it occurs when the coronary artery that supply blood to the heart muscle is compromised due to the accumulation of materials such as plaque/cholesterol atherosclerosis risk factors associated with coronary artery disease   men are susceptible at 45, women at 55 include age, gender, genetics, etc, Objective: To identify the patients at elevated risk for CAD, To identify patients required further investigation to confirm the diagnosis of CAD, To describe a management plan including lifestyle changes, medications, psychosocial support, cardiac rehabilitation, etc. Methods:  A prospective observational study was conducted for a period of 6 months, from CAD patients attending max cure hospital. The data was collected from the participants after consent. Relevant patient lifestyles and lab data were documented in the data collection form (DCF). Results: The study findings are according to parameter wise, age categorization defines that in 51-60 ranging age group 27.22% that is the highest percent affected people are observed with CAD.  Of the total number of subjects participated in the study (n=202) the gender-wise comparison males (144) are more than females (58).To observe patient region, urban people (68%) are mostly affected with CAD than rural people (32%). To identify risk factors of CAD, patients with DM (34.67%), HTN (23%), smoking (17.32%), alcohol (25.74%), and obesity (13.86%) are the major risk factors associated with CAD. Based on family history a total of 21 members were identified out of 202, among them with CAD were 7, with CKD were 6, with HTN were 5 and with DM were 3 members respectively.  According to the past history in a total of 202 members, patients with Cerebrovascular accidents were 4, patients with MI/UA were 20, and CKD were 4 respectively. Conclusion: Evaluation of risk factors in patients with coronary artery disease in a tertiary care hospital was observed. Age, Diabetes mellitus, Hypertension, Smoking, Alcohol, and Obesity are more causing risk factors than others.


2014 ◽  
Vol 36 (8) ◽  
pp. 690-699 ◽  
Author(s):  
Aydan Değerliyurt ◽  
Serap Teber ◽  
Gülhan Karakaya ◽  
Alev Güven ◽  
Esra Dağ Şeker ◽  
...  

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