scholarly journals Are blood groups related to the distribution and severity of COVID-19? A cross-sectional study in a tertiary care hospital in South India

2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Elaina Pasangha ◽  
Arkadeep Dhali ◽  
Christopher D'Souza ◽  
Soumya Umesh

Background: Blood groups are inherited traits that affect the susceptibility/severity of a disease. A clear relationship between coronavirus disease 2019 (COVID-19) and ABO blood groups is yet to be established in the Indian population. This study aimed to demonstrate an association of the distribution and severity of COVID-19 with ABO blood groups. Methods: A cross-sectional study was conducted after obtaining ethics approval (IEC 207/20) among hospitalized patients using in-patient records and analyzed on SPSS-25. Chi-square tests were used for the analysis of categorical data and independent sample t-test/Mann–Whitney U tests were used for continuous data. Results: The B blood group had the highest prevalence among COVID-19-positive patients. The AB blood group was significantly associated with acute respiratory distress syndrome (ARDS) (p = 0.03), sepsis (p = 0.02), and septic shock (p = 0.02). The O blood group was associated with significantly lower rates of lymphopenia and leucocytosis. However, no significant clinical association was seen in the O blood group. Conclusion: This study has demonstrated that blood groups have a similar distribution among patients hospitalized with COVID-19 in the South Indian population. Additionally, it preludes to a possible association between the AB blood group and ARDS, sepsis, and septic shock. Further studies having a larger representation of AB blood groups, especially in patients hospitalized for critical COVID-19, with adjustment for possible covariates, are warranted to provide a reliable estimate of the risk in the South Indian population.

2015 ◽  
Vol 5 (1) ◽  
pp. 16
Author(s):  
Gowri Natarajarathinam ◽  
AnushaV Rao ◽  
J Kannaperuman ◽  
Narasimman Muthusamy

2017 ◽  
Vol 7 (2) ◽  
pp. 103-106
Author(s):  
Sudhir R Patil ◽  
Komal D Walia ◽  
Surabhi Gigras ◽  
Veena HR

ABSTRACT Aim The aim of the study was to assess the relationship between obesity and periodontal status as well as evaluate its association with other demographic variables like age and gender among patients in KLE Society’s Institute of Dental Sciences, Bengaluru, Karnataka, India. Materials and methods A total of 200 patients (aged between 18 and 70 years) visiting the KLE Dental College in Bengaluru were analyzed for obesity and periodontal status. The body mass index (BMI) was used as an indicator of obesity and calculated as the ratio of the subject’s body weight (in kg) to the square of the height (in meters). Periodontal status was evaluated using community periodontal index (CPI). The relationship between BMI and periodontal status was assessed using binary multiple logistic regression analysis. Results Results indicated a positive correlation between BMI and periodontitis in the study group. Logistic regression analysis revealed that risk of periodontitis increases by 38% for each 1 kg/m2 increase in BMI. The risk of periodontitis increases with increase in age and influence of gender is not found to be significant. Conclusion Obesity could be a potential risk factor for periodontitis. Estimation of the BMI could, thus, be used in periodontal risk assessment. Clinical significance Obesity, as measured by BMI, is hypothesized to be involved in immunoinflammatory alterations, including periodontitis. The study also showed that obesity can be a potential risk factor for periodontitis. The BMI measurement should be used regularly as a part of periodontal risk assessment. Moreover, periodontists should counsel obese persons regarding the possible oral complications of obesity, to diminish morbidity for these individuals. How to cite this article Gigras S, Patil SR, Veena HR, Walia KD. Association between Obesity and Periodontitis in a South Indian Population: A Cross-sectional Study. J Contemp Dent 2017;7(2):103-106.


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