scholarly journals Brain Damage and Long-Lasting Sequels in Childhood: What Does Cerebral Palsy (CP) Mean at the Beginning of the XXI Century?

Author(s):  
D. Truscelli
Keyword(s):  
PEDIATRICS ◽  
1980 ◽  
Vol 65 (6) ◽  
pp. 1174-1176
Author(s):  
Saul Krugman

Sixteen years have elapsed since the last major epidemic of rubella in the United States. Prior to 1964, extensive outbreaks occurred at about six- to nine-year intervals. These outbreaks were associated with the birth of many thousands of infants with one or more of the following defects: cataracts, deafness, cardiac malformations, and brain damage causing mental retardation, cerebral palsy, or severe behavior disorders. In addition, many pregnancies were terminated by spontaneous or therapeutic abortions. This devastating "rubella problem" provided the motivation for the development of rubella vaccine. The live attenuated rubella vaccine was licensed for use in 1969—two to four years before the next anticipated epidemic.


2020 ◽  
Vol 6 (2) ◽  
pp. 175-186
Author(s):  
Agus Syahid

This study describes language disorders in the people with cerebral palsy and what kind of treatments to people with cerebral palsy related to language disorders. Cerebral palsy is a series of disorders with problems regulating muscle movements where it is as a result of some damage to the motor centers in the brain. Damage to the motor center in the brain that causes cerebral palsy can occur prenatal (before birth), perinatal (during the birth), or even postnatal (immediately after birth). There are several main problems that are often found and faced by children with cerebral palsy, they are: (1) difficulty in eating and swallowing caused by motor disturbances in the mouth, (2) difficulty in speaking, (3) difficulty in hearing, and (4) language disorders.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
A. Jensen ◽  
E. Hamelmann

Each year, thousands of children incur brain damage that results in lifelong sequelae. Therefore, based on experimental evidence, we explored the therapeutic potential of human cord blood, known to contain stem cells, to examine the functional neuroregeneration in a child with cerebral palsy after cardiac arrest. The boy, whose cord blood was stored at birth, was 2.5 years old and normally developed when global ischemic brain damage occurred resulting in a persistent vegetative state. Nine weeks later, he received autologous cord blood (91.7 mL, cryopreserved,5.75×10e8mononuclear cells) intravenously. Active rehabilitation (physio- and ergotherapy) was provided daily, follow-up at 2, 5, 12, 24, 30, and 40 months. At 2-months follow-up the boy’s motor control improved, spastic paresis was largely reduced, and eyesight was recovered, as did the electroencephalogram. He smiled when played with, was able to sit and to speak simple words. At 40 months, independent eating, walking in gait trainer, crawling, and moving from prone position to free sitting were possible, and there was significantly improved receptive and expressive speech competence (four-word sentences, 200 words). This remarkable functional neuroregeneration is difficult to explain by intense active rehabilitation alone and suggests that autologous cord blood transplantation may be an additional and causative treatment of pediatric cerebral palsy after brain damage.


2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Ana Alves-Pinto ◽  
Varvara Turova ◽  
Tobias Blumenstein ◽  
Renée Lampe

Recent imaging studies in cerebral palsy (CP) have described several brain structural changes, functional alterations, and neuroplastic processes that take place after brain injury during early development. These changes affect motor pathways as well as sensorimotor networks. Several of these changes correlate with behavioral measures of motor and sensory disability. It is now widely acknowledged that management of sensory deficits is relevant for rehabilitation in CP. Playing a musical instrument demands the coordination of hand movements with integrated auditory, visual, and tactile feedback, in a process that recruits multiple brain regions. These multiple demands during instrument playing, together with the entertaining character of music, have led to the development and investigation of music-supported therapies, especially for rehabilitation with motor disorders resulting from brain damage. We review scientific evidence that supports the use of musical instrument playing for rehabilitation in CP. We propose that active musical instrument playing may be an efficient means for triggering neuroplastic processes necessary for the development of sensorimotor skills in patients with early brain damage. We encourage experimental research on neuroplasticity and on its impact on the physical and personal development of individuals with CP.


2020 ◽  
Vol 5 (2) ◽  
pp. 132-138
Author(s):  
Bambang Trisnowiyanto ◽  
Tri Budi Santoso

Background: Cerebral palsy (CP) is a collection of motor disorders caused by brain damage that occur before, during or after birth which can be caused by many factors such as, congenital, genetic, inflation, infection and poisoning during pregnancy, trauma and metabolic disorders. Children with cerebral palsy will mostly have problems with posture. Muscular spasticity found in CP children is not only found in the muscles of the limbs but also the muscles forming posture (body posture), the condition of the body shape of children with CP will be exacerbated by the omission of postures that are not functional. Taping provides convenience in initiating motion, to help people with CP be able to move easily. The objectives of this study is to determine the effect of giving correction posture taping to the ability of motion of cerebral palsy children. Methods:  The design in this study is a quasi experiment with a pretest and posttest design. The research will be conducted on the CP community in Yogyakarta, namely the Wahana Cerebral Palsy Family (WKCP) for 8 weeks. The research instrument used in this study was  a blank check on the basic functional ability of GMFM. Results: After getting treatment in the form of Correction Posture Taping for 8 consecutive weeks, there was an increase in the functional ability of motion during sleep by 5.1385 with P = 0.000 (α <0.05), when seated by 1.0254 with P = 0.000 (α<0.05), when crawling by 0.44 with P = 0.000 (α <0.05), when standing and walking by 0.6523 with  P= 0.000 (α <0.05), when crawling by 0.32 with P = 0.000 (α <0.05). Conclusion: Based on the results of research and the results of data processing, there is the effect of posture taping correction on the functional ability of children with cerebral palsy.


PEDIATRICS ◽  
1964 ◽  
Vol 34 (3) ◽  
pp. 435-435
Author(s):  
SEYMOUR ZOGER

I was most interested in the paper by Dr. Waters in Pediatrics, 33:749, 1964. Dr. Waters has presented cogent reasons for not doing an exchange transfusion for a bilirubin of 20 mg/100 ml. I should like to refer to an earlier paper by Dr. Byers (Pediatrics 1955, 15:248), in which 23 patients are presented with cerebral palsy and hearing loss following erythroblastosis. Dr. Byers states in this paper that only 2 of the 23 patients had clinically recognized kernicterus in the newborn. It is not always easy to be certain that our jaundiced newborns are not going to develop later complications. The PSP binding technique offers some promise in this regard.


2001 ◽  
Vol 8 (1-2) ◽  
pp. 31-49 ◽  
Author(s):  
Mijna Hadders-Algra

The Neuronal Group Selection Theory (NGST) could offer new insights into the mechanisms directing motor disorders, such as cerebral palsy and developmental coordination disorder. According to NGST, normal motor development is characterized by two phases of variability. Variation is not at random but determined by criteria set by genetic information. Development starts with the phase of primary variability,during which variation in motor behavior is not geared to external conditions. At function-specific ages secondary variability starts, during which motor performance can be adapted to specific situations. In both forms, of variability, selection on the basis of afferent information plays a significant role. From the NGST point of view, children with pre- or perinatally acquired brain damage, such as children with cerebral palsy and part of the children with developmental coordination disorder, suffer from stereotyped motor behavior, produced by a limited repertoire or primary (sub)cortical neuronal networks. These children also have roblems in selecting the most efficient neuronal activity, due to deficits in the processing of sensory information. Therefore, NGST suggests that intervention in these children at early age should aim at an enlargement of the primary neuronal networks. With increasing age, the emphasis of intervention could shift to the provision of ample opportunities for active practice, which might form a compensation for the impaired selection.


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