scholarly journals CNV Analysis of the Correlation between Preoperative Lymph Node Metastasis and Prognosis of Early Tongue Cancer

2021 ◽  
Vol 12 (20) ◽  
pp. 6135-6144
Author(s):  
Xi Yang ◽  
Lu Fang ◽  
Chenping Zhang
2020 ◽  
Vol 25 (6) ◽  
pp. 1067-1071 ◽  
Author(s):  
Yasumasa Kakei ◽  
Hirokazu Komatsu ◽  
Tsutomu Minamikawa ◽  
Takumi Hasegawa ◽  
Masanori Teshima ◽  
...  

Abstract Background No clear consensus has been reached on the indication of supraomohyoid neck dissection (SOHND) for clinically positive lymph-node metastasis. Patients Consecutive 100 patients with previously untreated oral cancer treated at Kobe University Hospital were included in this study. All patients were clinically staged as anyTN1M0 and underwent radical dissection of the primary site and level I–V neck dissection as the initial treatment. Results None of the 100 patients had pathological lymph-node metastasis (pLN) to level V. pLN to level IV was observed in two patients with tongue cancer in whom clinical lymph-node metastasis was preoperatively observed at level II. Conclusions Level V may be excluded in the neck dissection for patients with N1 oral cancers. Level IV dissection should be considered in the patient with tongue cancer and clinical lymph-node metastasis at level II.


1992 ◽  
Vol 38 (1) ◽  
pp. 140-141 ◽  
Author(s):  
Noboru HAYASHI ◽  
Hirohisa OKAMURA ◽  
Hisao TANAKA ◽  
Kiyohiro OGOH ◽  
Masaki HASHIGUCHI ◽  
...  

2013 ◽  
Vol 59 (8) ◽  
pp. 550-554
Author(s):  
Kenji YAMAGATA ◽  
Osamu BABA ◽  
Naomi KANNO ◽  
Hiroki NAGAI ◽  
Toru YANAGAWA ◽  
...  

Author(s):  
Yasuyuki Asada ◽  
Chitoshi Teramura ◽  
Takuma Wada ◽  
Yoshisato Machida ◽  
Shinya Koshinuma ◽  
...  

We demonstrate the effectiveness of readministering cetuximab as a salvage chemotherapeutic agent after nivolumab administration to a patient with a recurrence of cervical lymph node metastasis after tongue cancer surgery. We can infer that the immunostimulatory effect of nivolumab and reactivation of cetuximab enhance the antitumor effect of the therapy.


1994 ◽  
Vol 20 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Ken OMURA ◽  
Sanzo TAKEMIYA ◽  
Fumiyuki SHIMADA ◽  
Shyujiro MAKINO ◽  
Tatsuaki KATAHASHI ◽  
...  

2019 ◽  
Vol 49 (4) ◽  
pp. 297-305 ◽  
Author(s):  
Nobuhiro Hanai ◽  
Takahiro Asakage ◽  
Naomi Kiyota ◽  
Akihiro Homma ◽  
Ryuichi Hayashi

Abstract The standard local treatment for early-stage tongue cancer with no clinical lymph node metastases is partial glossectomy. The frequency of occult lymph node metastasis is ~20–30%. Thus, whether prophylactic neck dissection with glossectomy or glossectomy alone should be performed has been a controversial issue since the 1980s. Both treatments have advantages and disadvantages; however, especially in cases involving prophylactic neck dissection, surgical invasion and complications including the cosmetic disadvantage caused by neck skin incision, accessory nerve paralysis or facial nerve (mandibular marginal branch) paralysis, stiffness of the shoulder or neck and a feeling of neck tightness have been considered issues that could be solved by providing less-invasive treatment to the 70–80% of patients without occult lymph node metastasis. A more accurate preoperative diagnosis and strict follow-up are required to provide minimally invasive treatment while ensuring the therapeutic effect. It is also necessary to narrow down the target based on the risk–benefit balance. The depth of invasion should be considered in cases involving oral cavity malignancies. This was also taken into account in recent revisions of eighth edition of the TNM Classification of Malignant Tumors and it is an important factor for N0 neck management. This review article summarizes previous and recent reports on neck management, focusing on the risk–benefit and future perspectives of the diagnosis and treatment of early-stage oral tongue cancer. This effort is an attempt to establish treatment from the patient’s point of view, with the patient’s quality of life taken into account.


Author(s):  
Masaru Konishi ◽  
Minoru Fujita ◽  
Kiichi Shimabukuro ◽  
Pongsapak Wongratwanich ◽  
Rinus Gerardus Verdonschot ◽  
...  

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