scholarly journals A clinicomycological study on chronic dermatophytosis in a tertiary care hospital in North India: An observational study

2021 ◽  
Vol 12 (4) ◽  
pp. 374-380
Author(s):  
Rabiya Bashir ◽  
Naina Kala Dogra ◽  
Bella Mahajan

Background: Chronic dermatophytosis is a considerable challenge in routine clinical practice. There is, however, scarce information available in the literature on its extent and characteristics. Aim: The aim of this study was to evaluate the host-related factors of chronic dermatophytosis and to identify the common fungal isolates. Methods: The study enrolled a total of 145 cases of chronic dermatophytosis attending the out-patient department of a tertiary care hospital in Jammu from November 2017 through October 2018. A detailed history was taken, followed by a clinical examination and investigations such as routine baseline investigations, an absolute eosinophil count, a wet mount for direct microscopy, and a fungal culture. Results: The most common presentation was tinea corporis with tinea cruris (33.1%), followed by tinea corporis alone. The majority of the patients (54.5%) had more than 20% of the body surface area involved. Most of the patients were manual workers (n = 44; 30.3%). The number of hours of sun exposure varied between 1 to 8.5 hours (mean ± SD: 3.53 ± 1.75 h). The fungal culture was positive in 65 (44.8%) patients. The most frequent isolates were Trichophyton mentagrophytes (53.8%), followed by Trichophyton rubrum (38.5%). Conclusion: We found Trichophyton mentagrophytes the predominant pathogen in chronic dermatophytosis, followed by Trichophyton rubrum, which demonstrates a changing trend as far as the causative organism is considered. Besides, various risk factors for chronicity such as prolonged sun exposure, lack of proper hygiene, wearing tight-fitting synthetic clothes, the use of topical steroids, and non-compliance to treatment were identified.

2021 ◽  
pp. 25-27
Author(s):  
P. Mohan ◽  
P. Revathi Guru ◽  
V. Sudha ◽  
L. Balamurugan ◽  
Pavithra Gunasekaran ◽  
...  

Paederus dermatitis is a form of irritant contact dermatitis due to contact with certain insects of the genus Paederus presenting with mostly erythematous linear lesions of sudden onset on exposed parts of the body. To study the clinico epi Aim: demiological features in patients with Paederus dermatitis. A retrospective analysis of clinicoepidemiological Materials & Methods: features of patients affected with Paederus dermatitis who had attended the Dermatology OPD, in a tertiary care hospital between January 2018 to December 2019 was done. All the required data had been collected from the OPD records and details were tabulated and analysed. A total of 56 patients had been affected with Result: Paederus dermatitis during the study period, of which 32 were males and 24 were females. 41out of 56 (73.21%) of patients presented between the months of August and December. Most common age group affected were between 11 to 30 yrs, with front and back of neck being the most common affected sites. In 42 out of the 56 patients the lesions resolved with post inammatory hyperpigmentation. Conclusion: Paederus dermatitis is a common condition that is often misdiagnosed and hence awareness is required for the clinicians and the general public to prevent it.


Author(s):  
Jitendra H. Hotwani ◽  
Nishikant H. Madkholkar

Background: Antimicrobials are used for prophylaxis and treatment of infections which occur following surgical procedures, to reduce the morbidity and mortality associated with surgical site infections (SSIs). A surgical site infection is an infection that occurs after surgery in the part of the body where the surgery took place. These are infections of the tissues, organs, or spaces exposed by surgeons during performance of an invasive procedure.Methods: A prospective, non-interventional, observational study in tertiary care hospital for duration of 9 months. Sample size was 330.Results: The prescription pattern shows that nitroimidazoles were the most commonly prescribed group of antimicrobials in 72% of patients followed by penicillins (58%) and cephalosporins (42%). Metronidazole (72%), amoxicillin and clavulanic acid (51.21%) ceftriaxone (20.90%) were most commonly prescribed antimicrobials in these groups. Two antimicrobials were prescribed in 47% patients with nitroimidazole and penicillins being the most commonly prescribed combination of antimicrobial. Three antimicrobials were prescribed in 25% patients and four antimicrobials in 8% patients. This shows trend towards polypharmacy. About 82% of antimicrobials were prescribed by brand names and 64% of total antimicrobials prescribed from outside the hospital pharmacy source. About 12.42% of patients changed antimicrobial therapy after culture and sensitivity report.Conclusions: Total duration, number of anti-microbial used was more in clean-contaminated, contaminated, dirty wound surgeries as compare to clean wound surgeries. Our study provides a framework for continuous prescription audit of antimicrobials in a hospital setting and thus can help in rational use of antimicrobials in post-operative surgical patients.


Author(s):  
Shivani Tyagi ◽  
Neha . ◽  
Ravinder Kaur ◽  
Deepti Rawat

Background: Onychomycosis is the fungal infec­tion of nail of which the incidence varies from 0.5-12% in India and around 5% worldwide.Onychomycosis is considered to be gender and age-related disease, being commoner in males and older adults in both genders. Apart from dermatophytes, other fungal agents like yeasts and non-dermatophyte moulds are increasingly being acknowledged as important etiological agents for the same. Our aim was to study the etiology of the nail infections in patients presenting to a dermatology department in a tertiary care hospital in central Delhi.Methods: This study included nail samples from patients of various age groups with suspected onychomycosis attending dermatology clinics in our hospital over a period of 2 years. For all samples, KOH wet mount microscopic examination followed by culture on Sabouraud’s dextrose agar was done. Growth of filamentous fungi and yeast obtained on SDA were identified using conventional microbiology techniques. Statistical analysis was performed using Epitools.Results: Of the total 1061 nail samples received, maximum prevalence seen in patients of age group 21 to 50 years. The positivity of onychomycosis was 57.02%. Out of culture positive samples, 24.62% grew dermatophytes and 75.37% grew non-dermatophytes (31.40% yeasts and 43.97% non-dermatophyte moulds). Trichophyton mentagrophytes was the most common (59.73%) dermatophyte followed by T. rubrum (23.49%) while among non-dermatophyte moulds; Aspergillus niger (20.68%) was the most common followed by A. flavus (16.54%) and others. Common yeasts included Candida spp. (65.79%) and Trichosporon spp. (28.95%).Conclusions: Non- dermatophytes are emerging as major etiological agents of onychomycosis which may be accounted various host factors. So, it becomes important to correctly identify the causative fungi to ensure appropriate treatment.


Author(s):  
Nisha Gupta ◽  
Rekha Sharma ◽  
Rukma L. Sharma

<p><strong>Background:</strong> Alopecia areata is a condition that is characterized by a well-defined round or oval patches of non-scaring hair loss in scalp or any hairy area of the body. Alopecia areata has become a major health problem faced by people all over the world. This research was done to ascertain the prevalence of alopecia areata in different age group and to study its association with autoimmune diseases and systemic illnesses.</p><p><strong>Methods:</strong> The present hospital based descriptive study includes 52 alopecia areata patients attending dermatology out-patient department.</p><p><strong>Results:</strong> It was seen that the disease can occur at any age group mostly affecting those between 21-40 years. The age of presentation varied from 14 to 48 years with male preponderance. It was found that arthritis was associated in 30.7%, ANA was positive in 7.7% and 12% had hypothyroidism. Eosinophilia was found in 34.6% and 7.7% had asthma among then.</p><p><strong>Conclusions:</strong> Our study shows that it could be associated with autoimmunity, thyroid abnormality, atopy and inflammation.</p>


2017 ◽  
Vol 6 (2) ◽  
pp. 183-187 ◽  
Author(s):  
Mahendrakar Madhuri A. ◽  
◽  
Hattangdi Shanta S. ◽  

2021 ◽  
pp. 35-37
Author(s):  
V. Pavani Sai Mounika ◽  
B. Mahalakshmi ◽  
CH. Srinivasa Rao ◽  
C. Naresh Kumar

Purpose: Tinea corporis (Ringworm) is a form of Dermatophytosis, which is a supercial fungal infection involving the trunk, legs, arms, commonly seen in countries like India. Although it is non-invasive and curable, its widespread nature and recurrence rates impose an economic burden on society in developing countries like India. This study aims at isolating different species causing this infection and studying their clinical patterns. Method: The study included the samples from the outpatients attending the Dermatology department of SVRRGGH, Tirupati, who were suspected of having Tinea corporis based on the clinical details, during the period from August 2018 to August 2019. The scrapings are examined by KOH mount and inoculated on Sabouraud's Dextrose agar and Dermatophyte test medium. The species are identied by colony morphology, Lactophenol cotton blue mount, biochemical reactions and standard procedures. Results: Out of 110 samples, overall positivity on direct microscopy is 78.2% (82), for Culture is 38.2%(42) and positive for both KOH and Culture are 38(34%). Out of 7 species isolated, the commonest isolate is Trichophyton mentagrophytes 19(45%), followed by Trichophyton rubrum 12(28%). Conclusion: Tinea corporis infections are more common in the 16-30 years age group, most of the patients belonging to low socioeconomic status with male predominance. Trichophyton species are commonly isolated from lesions in the waist and lower limbs, while Microsporum species from lesions on lower limbs. T. mentagrophytes was found to be the most common isolate and T. rubrum in case of extensive lesions.


Author(s):  
Santosh Kumar ◽  
RK Shrivastava ◽  
Arpit Jaiswal ◽  
Rakesh Yaduvanshi ◽  
CS Sharma ◽  
...  

ABSTRACT Introduction Psoriasis is an inflammatory skin disease, which may be persistent, disfiguring, and stigmatizing. The disease is frequent, with prevalence estimates ranging from 0.3 to 2.5%. It is characterized by thick, red, scaly lesion that may appear on any part of the body. Psoriasis is associated with significant psychological and psychiatric morbidity, experience of stigmatization, and decreased health-related quality of life (QOL). Aims and Objectives The aims of this study were to estimate psychiatric morbidity and QOL in patients with psoriasis and to study the specified demographic, psychological, social, and illness-related correlates of psychiatric morbidity and QOL. Materials and methods The study group consisted of 100 consecutive patients suffering from psoriasis and healthy controls. The assessment was done using General Health Questionnaire 12 items (GHQ-12), Psoriasis Area and Severity Index (PASI) scale, Hospital Anxiety and Depression Scale (HADS), and the World Health Organization Quality of Life BREF scale (WHOQOL-BREF). Patients were also subjected to clinical psychiatric examination. Only those subjects who scored ≥3 on GHQ-12 scale were administered HADS and WHOQOL-BREF. Results This study revealed statistically significant association between number of relapses and depression score and between severity of skin lesions (PASI score) and depressive score. Conclusion Psoriasis markedly worsens the global well-being of patients and their cohabitants, who experienced an impairment of their QOL and higher levels of anxiety and depression. How to cite this article Yaduvanshi R, Jaiswal A, Sharma CS, Kumar S, Ali R, Shrivastava RK, Rathoure PK. Psychiatric Morbidity and Quality of Life in Patients suffering from Psoriasis in a Tertiary Care Hospital. Int J Adv Integ Med Sci 2017;2(2):85-90.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Sundar Khadka ◽  
Jeevan Bahadur Sherchand ◽  
Dinesh Binod Pokharel ◽  
Bharat Mani Pokhrel ◽  
Shyam Kumar Mishra ◽  
...  

Background. Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, fungal treatment is best guided according to species isolated. This study was carried out to determine the clinical as well as mycological profile of superficial mycoses in a tertiary care hospital, Nepal.Methods. This was a prospective case-control laboratory based study conducted over a period of six months from January to June 2014 at Tribhuvan University Teaching Hospital, Nepal. A total of 200 specimens were collected from the patients suspected of superficial mycoses. The specimens were macroscopically as well as microscopically examined. The growth was observed up to 4 weeks.Results.Out of total 200 specimens from the patients suspected of superficial mycoses, tinea corporis 50 (25%) was most common clinical types. KOH mount was positive in 89 (44.5%) and culture was positive in 111 (55.5%).Trichophyton mentagrophytes44 (39.6%) was the most common isolate.Conclusions.The diagnostic yields of KOH mount and culture were found to be complementary to each other. Thus both the methods added with clinical findings are equally important to establish superficial mycosis.


Author(s):  
Tabindah Jahan ◽  
Anjum Farhana ◽  
Farhat Kanth

Background: Dermatophyte infections are a global health problem but very neglected in Kashmir. India. This work aimed at determining prevalence and spectrum of dermatophytosis isolated from patients attending tertiary care hospital Srinagar. Kashmir.Methods: A total of 510 samples of skin, hair and nail scrapings were collected and processed using standard microscopy (KOH) and cultural methods as per the standard protocol.Results: Out of 510 samples collected, 272 (53.33%) patients were confirmed cases of dermatophytosis (confirmed clinically and on fungal culture). The prevalence of dermatophytosis was significantly associated with age groups of participants with higher infection among those aged 18-32 which accounted for 35.29%, followed by age group 1-17 with 30.14%. Out of 510 samples, 110 ( 21.56%) were both KOH (microscopy) and culture positive, 162 (31.76%) cases were only culture positive and 130 (25.49%) clinical samples were only positive for fungal elements on microscopy. 133 (26.07%) fungal isolates were obtained which included both dermatophyte and non-dermatophytic fungi(excluded in this study). T. mentagrophytes had highest distribution 40.44% among dermatophytes species and T. Unguium 114 (41.96%) accounted for most common site for dermatophytic infections. Poor hygiene was predominant risk factor in 143 cases (52.57%). Patients from lower socioeconomic status were affected more than others (34.92%).Conclusions: In this study we have focused to determine the prevalence, clinical pattern and pathogenic profile of dermatophytosis according to the age, gender, site, and fungal distribution. Improvization of these conditions more accurately can result in decreased incidence of dermatophytosis in this area. 


Author(s):  
Ranbir Kumar Pandey ◽  
Dheeraj Kumar ◽  
Nisha Shrivastava ◽  
Nishant Kumar

<p class="abstract"><strong>Background:</strong> Nasal cavity may contain wide variety of masses within by which this organ differs from the rest of the body. Benign nasal and paranasal sinus masses are commonly encountered in clinical practice. The purpose of this study was to classify various types of sinonasal masses and characterize their clinico-epidemiological profile in a tertiary care hospital of Jharkhand. The objectives of the study was<strong> </strong> to evaluate the clinico-epidemiological profile of nasal masses in patients attending ear, nose, throat and head and neck surgery (ENT &amp; HNS) OPD of Rajendra Institute of Medical Sciences (RIMS), Ranchi from January 2013 to December 2015)  and to classify the nasal masses according to their percentage of occurrence<span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> This retrospective study was designed for evaluation of clinico-epidemiological data collected from admission register of ENT Dept. RIMS, Ranchi during the period of 2013 to 2015. Total sample size for this period was 240. Templates were generated in MS Excel sheets and analysis was done using SSPS software<span lang="EN-IN">.  </span></p><p class="abstract"><strong>Results:</strong> With the three year data analysis of 240 patients, we came up with the result that nasal masses were more common in age group of &lt;20 years (52%), occurred more in males (68.4%), most of the patients were tribals (72.9%), mostly from rural areas (60%), and maximum of them were diagnosed as antrochoanal polyps (37.9%). The most common presenting complain was nasal obstruction (85.8%), followed by nasal discharge (52.9%)<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Antrochoanal polyp is the most common type of nasal masses presenting mostly in tribal males from rural areas of Jharkhand, presenting with nasal obstruction<span lang="EN-IN">.</span></p>


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