scholarly journals Decision letter: Experience shapes activity dynamics and stimulus coding of VIP inhibitory cells

2019 ◽  
Author(s):  
Brice Bathellier ◽  
Georg B Keller
Keyword(s):  
Stimulus Coding ◽  
Activity Dynamics

scholarly journals Author response: Experience shapes activity dynamics and stimulus coding of VIP inhibitory cells

2020 ◽  
Author(s):  
Marina Garrett ◽  
Sahar Manavi ◽  
Kate Roll ◽  
Douglas R Ollerenshaw ◽  
Peter A Groblewski ◽  
...  
Keyword(s):  
Author Response ◽  
Stimulus Coding ◽  
Activity Dynamics

Mitotic Activity Dynamics in Recalcitrant Seeds Acer sachharinum during Maturation and Germination

HortScience ◽  
1998 ◽  
Vol 33 (3) ◽  
pp. 479c-479
Author(s):  
L. Kozeko ◽  
V. Troyan ◽  
L. Musatenko
Keyword(s):  
Cell Division ◽  
Mitotic Activity ◽  
Quiescent State ◽  
Activity Levels ◽  
Recalcitrant Seeds ◽  
Mature Embryos ◽  
Before And After ◽  
Orthodox Seeds ◽  
Mature Seeds ◽  
Activity Dynamics

In orthodox seeds the cell division within the embryo meristems arrests during maturation at embryo moisture content (MC) 65% to 47%, and the maturation completion and transition of seeds to quiescent state occurs at MC about 10%. The arrest of cycling happens asynchronously in different meristematic tissues during desiccation: first in shoot and then in root. The aim of this work was to define a mitotic activity dynamics in recalcitrant seeds with the high MC at maturation end and the absence of quiescent state characteristic of it. The object was seeds of Acer saccharinum, using widely for planting of greenery in Kiev city. The mitotic activity was determined in 0.5 mm of the embryo root pole (RP) and 0.5 mm of the shoot pole with embryo leaves (SP). The A. sachharinum seeds completed them maturation at MC 53% (FW basis). During maturation the mitotic index (MI) in RP decreased from 3.2% in immature seeds (at embryos MC 80%) to 0 in mature seeds and in SP–from 5.4% to 3.3%, respectively. Cell division in SP arrested by dehydration of mature embryos to MC 46% by PEG 6000 (30%). The seeds lost viability by desiccation to MC 34%. The mature seeds were able to germinate immediately after abscission. During seed germination the cell division reactived in RP and increased in SP already before root protrusion. In plantlets 10–15 mm long the MI increased to 8% in RP and 12% in SP. Thus, the strategy of immediate germination of recalcitrant A. sachharinum seeds includes a preservation of cell division in SP of mature embryos, in contrast with orthodox seeds, and high mitotic activity levels in meristems of germinating embryos before and after root protrusion.

scholarly journals Delayed neutralizing antibody response in the acute phase correlates with severe progression of COVID-19

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hitoshi Kawasuji ◽  
Yoshitomo Morinaga ◽  
Hideki Tani ◽  
Miyuki Kimura ◽  
Hiroshi Yamada ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Neutralization Test ◽  
Neutralizing Antibody ◽  
Pseudotyped Virus ◽  
Serum Samples ◽  
Neutralization Activity ◽  
Neutralizing Activity ◽  
Time Points ◽  
Moderate Disease ◽  
Activity Dynamics

AbstractAdaptive immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dynamics remain largely unknown. The neutralizing antibody (NAb) levels in patients with coronavirus disease 2019 (COVID-19) are helpful for understanding the pathology. Using SARS-CoV-2 pseudotyped virus, serum sample neutralization values in symptomatic COVID-19 patients were measured using the chemiluminescence reduction neutralization test (CRNT). At least two sequential serum samples collected during hospitalization were analyzed to assess NAbs neutralizing activity dynamics at different time points. Of the 11 patients, four (36.4%), six (54.5%), and one (9.1%) had moderate, severe, and critical disease, respectively. Fifty percent neutralization (N50%-CRNT) was observed upon admission in 90.9% (10/11); all patients acquired neutralizing activity 2–12 days after onset. In patients with moderate disease, neutralization was observed at earliest within two days after symptom onset. In patients with severe-to-critical disease, neutralization activity increased, plateauing 9–16 days after onset. Neutralization activity on admission was significantly higher in patients with moderate disease than in patients with severe-to-critical disease (relative % of infectivity, 6.4% vs. 41.1%; P = .011). Neutralization activity on admission inversely correlated with disease severity. The rapid NAb response may play a crucial role in preventing the progression of COVID-19.

scholarly journals Enhancing Task fMRI Preprocessing via Individualized Model-Based Filtering of Intrinsic Activity Dynamics

2020 ◽  
Author(s):  
Matthew F. Singh ◽  
Anxu Wang ◽  
Michael Cole ◽  
ShiNung Ching ◽  
Todd S. Braver
Keyword(s):  
Statistical Power ◽  
Brain Activity ◽  
Intrinsic Activity ◽  
Bold Signal ◽  
Group Level ◽  
Temporal Precision ◽  
Brain Responses ◽  
Evoked Activity ◽  
Activity Dynamics ◽  
Do So

AbstractBrain responses recorded during fMRI are thought to reflect both rapid, stimulus-evoked activity and the propagation of spontaneous activity through brain networks. In the current work we describe a method to improve the estimation of task-evoked brain activity by first “filtering-out” the intrinsic propagation of pre-event activity from the BOLD signal. We do so using Mesoscale Individualized NeuroDynamic (MINDy; [1]) models built from individualized resting-state data (MINDy-based Filtering). After filtering, time-series are analyzed using conventional techniques. Results demonstrate that this simple operation significantly improves the statistical power and temporal precision of estimated group-level effects. Moreover, estimates based upon our technique better generalize between tasks measuring the same construct (cognitive control) and better predict individual differences in behavior. Thus, by subtracting the propagation of previous activity, we obtain better estimates of task-related neural activity.

scholarly journals Correction: Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Ying Sun ◽  
Carlos Blanco-Centurion ◽  
Emmaline Bendell ◽  
Aurelio Vidal-Ortiz ◽  
Siwei Luo ◽  
...  
Keyword(s):  
Gabaergic Neurons ◽  
Activity Dynamics

Microbial community distribution and activity dynamics of granular biomass in a CANON reactor

2010 ◽  
Vol 44 (15) ◽  
pp. 4359-4370 ◽  
Author(s):  
Jose Vázquez-Padín ◽  
Anuska Mosquera-Corral ◽  
Jose Luis Campos ◽  
Ramón Méndez ◽  
Niels Peter Revsbech
Keyword(s):  
Microbial Community ◽  
Granular Biomass ◽  
Activity Dynamics

scholarly journals Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Yu Muta ◽  
Yoshihisa Fujita ◽  
Kenta Sumiyama ◽  
Atsuro Sakurai ◽  
M. Mark Taketo ◽  
...  
Keyword(s):  
Erk Activity ◽  
Activity Dynamics
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