scholarly journals An open-source, high-performance tool for automated sleep staging

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Raphael Vallat ◽  
Matthew P Walker

The clinical and societal measurement of human sleep has increased exponentially in recent years. However, unlike other fields of medical analysis that have become highly automated, basic and clinical sleep research still relies on human visual scoring. Such human-based evaluations are time-consuming, tedious, and can be prone to subjective bias. Here, we describe a novel algorithm trained and validated on +30,000 hr of polysomnographic sleep recordings across heterogeneous populations around the world. This tool offers high sleep-staging accuracy that matches human scoring accuracy and interscorer agreement no matter the population kind. The software is designed to be especially easy to use, computationally low-demanding, open source, and free. Our hope is that this software facilitates the broad adoption of an industry-standard automated sleep staging software package.

2021 ◽  
Author(s):  
Raphael Vallat ◽  
Matthew P Walker

The creation of a completely automated sleep-scoring system that is highly accurate, flexible, well validated, free and simple to use by anyone has yet to be accomplished. In part, this is due to the difficulty of use of existing algorithms, algorithms having been trained on too small samples, and paywall demotivation. Here we describe a novel algorithm trained and validated on +27,000 hours of polysomnographic sleep recordings across heterogeneous populations around the world. This tool offers high sleep-staging accuracy matching or exceeding human accuracy and interscorer agreement no matter the population kind. The software is easy to use, computationally low-demanding, open source, and free. Such software has the potential to facilitate broad adoption of automated sleep staging with the hope of becoming an industry standard.


2011 ◽  
pp. 1265-1271
Author(s):  
Javier Soriano ◽  
Sonia Frutos ◽  
Jiménez. Miguel

Open source communities are one of the most successful-- and least appreciated--examples of high-performance collaboration and community building on the Internet today. Open source communities began as loosely organized, ad-hoc communities of contributors from all over the world who shared an interest in meeting a common need. However, the organization of these communities has proven to be very flexible and capable of carrying out all kind of developments, ranging from minor projects to huge programs such as Apache (Höhn, & Herr, 2004; Mockus, Fielding, & Herbsleb, 2005).


Author(s):  
Laimonis Zacs ◽  
Anita Jansone

<p><em>In this paper the authors describe solution for solving various analytical problems in <em>E-learning, Course Management Systems like Moodle by using HPC</em></em> <em>(High Performance Computing) and Apache Hadoop open source technologies in Liepaja University. The problem is that nowadays there are collecting huge amounts of analytics data from several gigabytes to petabytes, which is hard to store, process, analyse and visualize. This article reflects one of the solutions concerning distributed parallel processing of huge amounts of data across inexpensive, industry-standard servers that can store and process the data, can scale without limits and provides technological opportunities of reliable, scalable and distributed computing.</em><em> </em></p><p> </p>


2019 ◽  
Author(s):  
Joel T. Collins ◽  
Joe Knapper ◽  
Julian Stirling ◽  
Joram Mduda ◽  
Catherine Mkindi ◽  
...  

AbstractOptical microscopes are an essential tool for both the detection of disease in clinics, and for scientific analysis. However, in much of the world access to high-performance microscopy is limited by both the upfront cost and maintenance cost of the equipment. Here we present an open-source, 3D-printed, and fully-automated laboratory microscope, with motorised sample positioning and focus control. The microscope is highly customisable, with a number of options readily available including trans- and epi-illumination, polarisation contrast imaging, and epi-florescence imaging. The OpenFlexure Microscope has been designed to enable low-volume manufacturing and maintenance by local personnel, vastly increasing accessibility. We have produced over 100 microscopes in Tanzania and Kenya for educational, scientific, and clinical applications, demonstrating that local manufacturing can be a viable alternative to international supply chains that can often be costly, slow, and unreliable.


Author(s):  
Javier Soriano ◽  
Sonia Frutos ◽  
Jiménez. Miguel

Open source communities are one of the most successful-- and least appreciated--examples of high-performance collaboration and community building on the Internet today. Open source communities began as loosely organized, ad-hoc communities of contributors from all over the world who shared an interest in meeting a common need. However, the organization of these communities has proven to be very flexible and capable of carrying out all kind of developments, ranging from minor projects to huge programs such as Apache (Höhn, & Herr, 2004; Mockus, Fielding, & Herbsleb, 2005).


2020 ◽  
Vol 16 ◽  
Author(s):  
Kirubanandam Grace Pavithra ◽  
Vasudevan Jaikumar ◽  
Ponnusamy Senthil Kumar ◽  
PanneerSelvam SundarRajan

Background: Many antibiotics were widely used as medication based on their distinctive features. Among them, sulphonamides were commonly used, however their recalcitrant nature makes them difficult to dispose. Hence, their interaction with environment and analytic technique requires considerable attention globally. Objective: Therefore, this review aimed to provide detailed discussion about environmental as well as human health behaviour and analytic techniques corresponding to sulphonamides. Methods: Various results and discussion were extracted from technical journals and books published by different researchers from all over the world. The cited bibliographic references were intentionally investigated in order to extract relevant information related to proposed work. Results: In this review, the determination techniques such as UV-spectroscopy, Enthalpimetry, Immunosensor, Chromatography, Chemiluminescence, Photoinduced fluorometric determination, Capillary electrophoresis for sulphonamide determination were discussed in detail. Among them, High performance liquid chromatography (HPLC) and UV-spectroscopy was effective and extensively used for screening sulphonamide. Conclusion: Knowing the quantification and behaviour of sulphonamide in aqueous solution is mandatory to opt the suitable wastewater treatment required. Hence, choosing appropriate high precision and feasible screening techniques is necessary, which can be attained with this review.


Author(s):  
Shinji Kobayashi ◽  
Luis Falcón ◽  
Hamish Fraser ◽  
Jørn Braa ◽  
Pamod Amarakoon ◽  
...  

Objectives: The emerging COVID-19 pandemic has caused one of the world’s worst health disasters compounded by social confusion with misinformation, the so-called “Infodemic”. In this paper, we discuss how open technology approaches - including data sharing, visualization, and tooling - can address the COVID-19 pandemic and infodemic. Methods: In response to the call for participation in the 2020 International Medical Informatics Association (IMIA) Yearbook theme issue on Medical Informatics and the Pandemic, the IMIA Open Source Working Group surveyed recent works related to the use of Free/Libre/Open Source Software (FLOSS) for this pandemic. Results: FLOSS health care projects including GNU Health, OpenMRS, DHIS2, and others, have responded from the early phase of this pandemic. Data related to COVID-19 have been published from health organizations all over the world. Civic Technology, and the collaborative work of FLOSS and open data groups were considered to support collective intelligence on approaches to managing the pandemic. Conclusion: FLOSS and open data have been effectively used to contribute to managing the COVID-19 pandemic, and open approaches to collaboration can improve trust in data.


2017 ◽  
Vol 45 (4) ◽  
pp. 319-328 ◽  
Author(s):  
Lawrence V. Stanislawski ◽  
Kornelijus Survila ◽  
Jeffrey Wendel ◽  
Yan Liu ◽  
Barbara P. Buttenfield

2018 ◽  
Vol 199 ◽  
pp. 09001
Author(s):  
Renaud Franssen ◽  
Serhan Guner ◽  
Luc Courard ◽  
Boyan Mihaylov

The maintenance of large aging infrastructure across the world creates serious technical, environmental, and economic challenges. Ultra-high performance fibre-reinforced concretes (UHPFRC) are a new generation of materials with outstanding mechanical properties as well as very high durability due to their extremely low permeability. These properties open new horizons for the sustainable rehabilitation of aging concrete structures. Since UHPFRC is a young and evolving material, codes are still either lacking or incomplete, with recent design provisions proposed in France, Switzerland, Japan, and Australia. However, engineers and public agencies around the world need resources to study, model, and rehabilitate structures using UHPFRC. As an effort to contribute to the efficient use of this promising material, this paper presents a new numerical modelling approach for UHPFRC-strengthened concrete members. The approach is based on the Diverse Embedment Model within the global framework of the Disturbed Stress Field Model, a smeared rotating-crack formulation for 2D modelling of reinforced concrete structures. This study presents an adapted version of the DEM in order to capture the behaviour of UHPFRC by using a small number of input parameters. The model is validated with tension tests from the literature and is then used to model UHPFRC-strengthened elements. The paper will discuss the formulation of the model and will provide validation studies with various tests of beams, columns and walls from the literature. These studies will demonstrate the effectiveness of the proposed modelling approach.


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