scholarly journals Role of Opioid-Involved Drug Interactions in Chronic Pain Management

2019 ◽  
Vol 119 (12) ◽  
pp. 839 ◽  
Author(s):  
Kevin T. Bain ◽  
Calvin H. Knowlton
Keyword(s):  
Chronic Pain ◽  
Pain Management ◽  
Drug Interactions ◽  
Chronic Pain Management

The Role of Cannabidiol (CBD) in Chronic Pain Management: An Assessment of Current Evidence

2020 ◽  
Vol 24 (2) ◽  
Author(s):  
Shafik Boyaji ◽  
Justin Merkow ◽  
R. Noel M. Elman ◽  
Alan D. Kaye ◽  
R. Jason Yong ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Pain Management ◽  
Current Evidence ◽  
Chronic Pain Management

The Role of Childhood and Adulthood Abuse Among Women Presenting for Chronic Pain Management

2001 ◽  
Vol 17 (4) ◽  
pp. 359-364 ◽  
Author(s):  
Carmen R. Green ◽  
Heather Flowe-Valencia ◽  
Lee Rosenblum ◽  
Alan R. Tait
Keyword(s):  
Chronic Pain ◽  
Pain Management ◽  
Chronic Pain Management

Is Neuraxial Clonidine a Safer Alternative to Opioids for Chronic Pain? An Alternative Worth Exploring

2020 ◽  
pp. 1-7
Author(s):  
Nagy Mekhail ◽  
Nagy Mekhail ◽  
Shrif Costandi ◽  
Alaa Abd-Elsayed ◽  
Gregory Fiore ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Pain Management ◽  
Potential Role ◽  
Common Side Effect ◽  
Chronic Pain Management ◽  
Inclusion Criteria ◽  
Opioid Use ◽  
Levels Of Evidence ◽  
The Past

Objective: Exploring the potential role of clonidine as an alternative to the currently available neuraxial medication options for the management of chronic pain. Methods: A comprehensive literature search was conducted investigating the treatment of chronic pain using clonidine over the past 73 years. A stepwise filtering approach was used to obtain articles addressing neuraxial treatment of chronic pain in adults. Selected articles were assessed for their levels of evidence followed by a discussion of their contribution to the understanding of the role of clonidine in chronic pain management. Results: Out of 1,035 articles that described the administration of clonidine for chronic pain management, seven articles met all of the inclusion criteria. Their levels of evidence ranged from 1a to 4 (Oxford Centre CEBM). Neuraxial administration of clonidine was found to be effective in the treatment of chronic pain, often exhibiting a synergistic effect with other analgesics to provide pain reduction with reduced opioid use. The most common side effect was hypotension, in some cases reported to have been serious. Conclusion: The use of neuraxial clonidine, in either a primary or adjunctive role, appears promising as an effective treatment for chronic pain.

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