scholarly journals Kimura Disease Presenting as Right Parotid Swelling and Neck Lymphadenopathy

Cureus ◽  
2021 ◽  
Author(s):  
Madan Shivakumar ◽  
Naveen Kumar Gaur ◽  
Sharmila Balaji ◽  
Oseen Shaikh ◽  
Uday Kumbhar
Rheumatology ◽  
2019 ◽  
Vol 58 (Supplement_3) ◽  
Author(s):  
Arti Mahto ◽  
Fang En Sin ◽  
Amy Macbrayne ◽  
Vanessa Morris

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Fatemah Faras ◽  
Fawaz Abo-Alhassan ◽  
Khalid Al-Sebeih ◽  
Jassem Bastaki

Kimura disease is a rare, benign, chronic inflammatory swelling of the subcutaneous tissue, lymph nodes, and glandular tissue. Characteristic features of the disease include, but not limited to, painless subcutaneous head and neck swelling, blood and tissue eosinophilia, and markedly elevated immunoglobulin E (IgE) levels. Herein, we report a rare case of Kimura disease manifesting as synchronous bilateral parotid swelling of 12 years duration in a 33-year-old Middle-Eastern man. To our knowledge only few cases have been reported in the literature involving bilateral parotid glands, and this is the first case to be reported in the Middle East.


2007 ◽  
Vol 137 (2) ◽  
pp. 306-311 ◽  
Author(s):  
Hiroshi Iwai ◽  
Kaoru Nakae ◽  
Koshi Ikeda ◽  
Manabu Ogura ◽  
Makoto Miyamoto ◽  
...  

OBJECTIVES: To establish a preoperative diagnostic system and examine prognostic factors for Kimura disease. STUDY DESIGN: Retrospective study. SETTING: Hospital records were reviewed for nine cases of Kimura disease treated in our department. Preoperative eosinophil counts for 74 cases with untreated malignancy in the parotid gland were also examined. RESULTS: Parotid swelling with inhomogeneities and subcutaneous invasion on magnetic resonance imaging and eosinophils > 10.5 percent in Asian patients clearly indicates Kimura disease. Eosinophils > 50 percent, serum IgE levels > 10,000 IU/mL, and multifocal lesions outside salivary glands are prognostic factors suggesting disease recurrence. CONCLUSIONS: A preoperative decision based on our diagnostic criteria and prognostic factors should lead to better therapeutic outcomes for Kimura disease, for which a definitive treatment policy has never been determined.


Author(s):  
Gi Hwa Jung ◽  
Byung Han Cho ◽  
Bum Jun Kim ◽  
Jae-Yol Lim ◽  
Young-Mo Kim
Keyword(s):  

2021 ◽  
pp. 116-123
Author(s):  
Roald Vissing-Uhre ◽  
Alastair Hansen ◽  
Susanne Frevert ◽  
Ditte Hansen

Kimura disease (KD) is a chronic, inflammatory disorder with slowly developing subcutaneous tumor-like swellings, often occurring in the head and neck region. KD is diagnosed based on histology, elevated levels of immunoglobulin type E, and increased peripheral eosinophil granulocytes. KD may coexist with glomerular renal diseases, and this case report is based on a patient with KD-associated membranous nephropathy. Patients with membranous nephropathy without KD have demonstrated responsiveness to treatment with monoclonal anti-CD20 antibodies. This case report is the first to investigate the effect of rituximab treatment in a patient with KD-associated membranous nephropathy. A 30-year-old Italian man living in Denmark was diagnosed with Kimura’s disease based on subcutaneous nodules with eosinophil angiolymphoid hyperplasia. The patient was admitted to the hospital due to nephrotic syndrome. Serology showed eosinophil granulocytosis and negative PLA2-receptor antibody. Renal biopsy showed membranous nephropathy, and the patient was treated with systemic methylprednisolone followed by cyclosporin and then cyclophosphamide with only partial remission. Ultimately, treatment with intravenous rituximab was initiated, which resulted in overall remission and no nephrotic relapses at 30 months of follow-up. Thus, intravenous rituximab effectively decreased proteinuria and prevented nephrotic relapses in a patient with treatment-refractory membranous nephropathy due to KD.


2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Geoffrey Williams ◽  
Carlos Neblett ◽  
Jade Arscott ◽  
Sheena McLean ◽  
Shereika Warren ◽  
...  

Abstract Kimura disease (KD) is a chronic, inflammatory, benign disorder endemic to Asia that typically manifests as a triad of painless masses in the head and neck region, elevated eosinophils and serum immunoglobulin. It usually affects young men in their second and third decades of life and is rarely seen outside of the orient. This is a report of a case of KD in a young man of African descent who presented with a cheek mass. KD was not included in our differential diagnosis, and this report highlights the need to consider this entity, which can be easily missed due to its rarity in the Western world. There is no cure for the disease, and management includes medical and surgical modalities, but local recurrence or relapse is not uncommon.


Author(s):  
Ming-Jay Hwang ◽  
Julia Yu-Fong Chang ◽  
Andy Sun ◽  
Chun-Pin Chiang
Keyword(s):  

2011 ◽  
Vol 18 (5) ◽  
pp. 253-255
Author(s):  
Manoj K. Goel ◽  
Deven Juneja ◽  
Sai Kiran Chaudhuri ◽  
Ajay Kumar ◽  
Sudhir Jain
Keyword(s):  

Author(s):  
F. Dezoteux ◽  
R. Dubois ◽  
G. Lefèvre ◽  
J.P. Lecoutre ◽  
D. Staumont-Sallé ◽  
...  
Keyword(s):  

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