Comparison of Pediatric Sequential Organ Failure Assessment and Pediatric Risk of Mortality III Score as Mortality Prediction in Pediatric Intensive Care Unit

Pendahuluan: Society of Critical Care Medicine (SCCM) dan European Society of Intensive Care Medicine (ESICM) mengeluarkan definisi sepsis terbaru (Sepsis-3) yaitu disfungsi organ yang mengancam jiwa akibat disregulasi respon imun pejamu terhadap infeksi. Skor Sequential Organ Failure Assessment (SOFA) telah dipilih dan divalidasi sebagai sistem penilaian untuk mengukur disfungsi organ dikarenakan skor SOFA pada pasien dewasa dengan kecurigaan infeksi, sebanding atau bahkan lebih unggul daripada sistem penilaian lainnya dalam membedakan mortalitas rumah sakit. Untuk mengadaptasi definisi Sepsis-3, skor SOFA diadaptasi dan divalidasi untuk pasien anak-anak yang mengidap sakit kritis (pSOFA) dengan menggunakan kriteria yang telah disesuaikan berdasarkan usia. Hasil penelitian menunjukan perkiraan mortalitas pada pSOFA saat waktu kedatangan, hari 2, 4, 7 dan 14 setelah masuk Pediatric Intensive Care Unit (PICU) lebih baik dibandingkan skor disfungsi organ lainnya. Evaluasi serial dari skor pSOFA pada hari pertama setelah masuk PICU juga sangat baik dalam memprediksi prognosis dari pasien pediatri onkologi yang memakai ventilator selama 3 hari, anak-anak dengan sepsis di PICU dan berguna untuk memprediksi mortalitas 30 hari pada populasi PICU, namun kurang berhasil dalam memprediksi lamanya pasien untuk dirawat di PICU.

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Paediatric sequential organ failure assessment (pSOFA) score: a new mortality prediction score in the paediatric intensive care unit

Anales de Pediatría (English Edition) ◽

10.1016/j.anpede.2019.11.001 ◽

2020 ◽

Vol 92 (5) ◽

pp. 277-285

Author(s):

Ghada Mohamed El-Mashad ◽

Muhammad Said El-Mekkawy ◽

Mohamed Helmy Zayan

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Sequential Organ Failure Assessment ◽

Organ Failure ◽

Paediatric Intensive Care Unit ◽

Mortality Prediction ◽

Paediatric Intensive Care ◽

Prediction Score ◽

Failure Assessment

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Prevalence of multiple organ dysfunction in the pediatric intensive care unit: Pediatric Risk of Mortality III versus Pediatric Logistic Organ Dysfunction scores for mortality prediction

Revista Brasileira de Terapia Intensiva ◽

10.5935/0103-507x.20170029 ◽

2017 ◽

Vol 29 (2) ◽

Cited By ~ 3

Author(s):

Azza Abd Elkader El Hamshary ◽

Seham Awad El Sherbini ◽

HebatAllah Fadel Elgebaly ◽

Samah Abdelkrim Amin

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Organ Dysfunction ◽

Pediatric Intensive Care ◽

Multiple Organ ◽

Mortality Prediction ◽

Multiple Organ Dysfunction ◽

Logistic Organ Dysfunction ◽

Risk Of Mortality

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Multicenter validation of the neonatal sequential organ failure assessment score for prognosis in the neonatal intensive care unit

The Journal of Pediatrics ◽

10.1016/j.jpeds.2021.05.037 ◽

2021 ◽

Author(s):

James L. Wynn ◽

Anoop Mayampurath ◽

Kyle Carey ◽

Susan Slattery ◽

Bree Andrews ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Sequential Organ Failure Assessment ◽

Organ Failure ◽

Neonatal Intensive Care ◽

Assessment Score ◽

Failure Assessment ◽

Multicenter Validation

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Establishment of a prognostic model based on the Sequential Organ Failure Assessment score for patients with first-time acute myocardial infarction

Journal of International Medical Research ◽

10.1177/03000605211011976 ◽

2021 ◽

Vol 49 (5) ◽

pp. 030006052110119

Author(s):

Shuai Zheng ◽

Jun Lyu ◽

Didi Han ◽

Fengshuo Xu ◽

Chengzhuo Li ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Intensive Care Unit ◽

Intensive Care ◽

Sequential Organ Failure Assessment ◽

Organ Failure ◽

Sofa Score ◽

Cardiovascular Events ◽

Failure Assessment ◽

First Time

Objective This study aimed to identify the prognostic factors of patients with first-time acute myocardial infarction (AMI) and to establish a nomogram for prognostic modeling. Methods We studied 985 patients with first-time AMI using data from the Multi-parameter Intelligent Monitoring for Intensive Care database and extracted their demographic data. Cox proportional hazards regression was used to examine outcome-related variables. We also tested a new predictive model that includes the Sequential Organ Failure Assessment (SOFA) score and compared it with the SOFA-only model. Results An older age, higher SOFA score, and higher Acute Physiology III score were risk factors for the prognosis of AMI. The risk of further cardiovascular events was 1.54-fold higher in women than in men. Patients in the cardiac surgery intensive care unit had a better prognosis than those in the coronary heart disease intensive care unit. Pressurized drug use was a protective factor and the risk of further cardiovascular events was 1.36-fold higher in nonusers. Conclusion The prognosis of AMI is affected by age, the SOFA score, the Acute Physiology III score, sex, admission location, type of care unit, and vasopressin use. Our new predictive model for AMI has better performance than the SOFA model alone.

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