INTRODUCTION: Acute kidney injury is a common occurrence in ICU admissions causing increased
morbidity and mortality. Present study aimed to determine the causes and prognostic factors of acute
kidney injury in intensive care unit.
MATERIAL AND METHODS: This Hospital based Cross sectional Study was conducted at a tertiary care Hospital and
Research Center, including 100 patients aged >18 years with Acute Kidney Injury admitted in ICU from the period of October
2018 to June 2020. Patients with chronic renal disease, previous renal transplantation, congenital renal disease were excluded
from the study.
RESULTS: Most of the patients (63%) were aged above 50 years. Diabetes was found in 55% and hypertension in 26% of AKI
cases. Most common cause identied were sepsis, CLD, renal, CNS and CVD. Hypotension occurred in 48% patients, while
oliguria occurred in 45% patients. Ventilatory support was required by 43% patients, while 31% patients required
haemodialysis. Mortality rate in AKI was 51%. Mortality was signicantly associated with advanced age, presence of
Diabetes, and RIFLE criteria. Spot urine <40 meq/L, hyperkalemia, serum creatinine >4 mg/dl, blood urea >100 mg/dl and
acidosis were associated with higher mortality.
CONCLUSION: Continuous monitoring parameters like Spot Fe Na, Serum Potasium and pH especially in patients at risk, like
elderly patients with diabetes, those with sepsis, can help in early identication and appropiate management, thus reduce the
incidence or severity of AKI.
Acute Kidney Injury in Patients With Suspected Pulmonary Embolism: A Retrospective Study of the Incidence, Risk Factors, and Outcomes in a Tertiary Care Hospital in Saudi Arabia
