scholarly journals An Interesting Case of Klebsiella Pneumoniae Pylephlebitis

Cureus ◽  
2022 ◽  
Author(s):  
Sneha Adidam ◽  
Lorenzo Leys ◽  
Siham Mahgoub
2015 ◽  
Vol 59 (8) ◽  
pp. 5065-5068 ◽  
Author(s):  
Costas C. Papagiannitsis ◽  
Monika Dolejska ◽  
Radoslaw Izdebski ◽  
Hana Dobiasova ◽  
Vendula Studentova ◽  
...  

ABSTRACTIMP-8 metallo-β-lactamase was identified inKlebsiella pneumoniaesequence type 252 (ST252), isolated in a Portuguese hospital in 2009.blaIMP-8was the first gene cassette of a novel class 3 integron, In1144, also carrying theblaGES-5,blaBEL-1, andaacA4cassettes. In1144 was located on a ColE1-like plasmid, pKP-M1144 (12,029 bp), with a replication region of limited nucleotide similarity to those of other RNA-priming plasmids, such as pJHCMW1. In1144 and pKP-M1144 represent an interesting case of evolution of resistance determinants in Gram-negative bacteria.


2017 ◽  
Vol 23 ◽  
pp. 132-133
Author(s):  
Shilpi Singh ◽  
Andrea George ◽  
Arjun Theertham ◽  
Mohsen Zena ◽  
John Christopher Gallagher

1994 ◽  
Vol 71 (06) ◽  
pp. 768-772 ◽  
Author(s):  
Gerhard Dickneite ◽  
Jörg Czech

SummaryRats which were infected with the gramnegative pathogen Klebsiella pneumoniae develop disseminated intravascular coagulation (DIC), multi-organ failure (MOF) and finally die in a septic shock. We investigated the therapeutic effect of antibiotic (tobramycin) treatment combined with the infusion of the highly specific thrombin inhibitor rec. hirudin. Although administration of 2 mg/kg tobramycin alone leads to a decrease of the bacterial burden, DIC could not be prevented. Infusion of rec. hirudin (0.25 mg/kg x h) for 4 h (start of treatment 1 h post infection), in addition to a bolus administration of tobramycin, led to an amelioration of DIC parameters as fibrinogen, thrombin-antithrombin complex (TAT) and platelets. Serum transaminase levels (GOT, GPT) as a marker of MOF were significantly improved by rec. hirudin, the T50 value increased from 17 h in the tobramycin group to 42 h in the tobramycin + rec. hirudin giuup, muilality rates were 90% or 60%, respectively. Combination of heparin (10011/kg x h) and tobramycin was not effective on survival.


Author(s):  
Davor Petrović ◽  
Vida Čulić ◽  
Zofia Swinderek-Alsayed

AbstractJoubert syndrome (JS) is a rare congenital, autosomal recessive disorder characterized by a distinctive brain malformation, developmental delay, ocular motor apraxia, breathing abnormalities, and high clinical and genetic heterogeneity. We are reporting three siblings with JS from consanguineous parents in Syria. Two of them had the same homozygous c.2172delA (p.Trp725Glyfs*) AHI1 mutation and the third was diagnosed prenatally with magnetic resonance imaging. This pathogenic variant is very rare and described in only a few cases in the literature. Multinational collaboration could be of benefit for the patients from undeveloped, low-income countries that have a low-quality health care system, especially for the diagnosis of rare diseases.


2004 ◽  
Vol 221 (S 5) ◽  
Author(s):  
A Scharipow ◽  
M Blum ◽  
K Ende ◽  
B Knau

2020 ◽  
Vol 40 (2) ◽  
Author(s):  
Haruo Nakagawa

Akin to the previous, 2014 event, with no data on voter ethnicity, no exit polls, and few post-election analyses, the 2018 Fiji election results remain something of a mystery despite the fact that there had been a significant swing in voting in favour of Opposition political parties. There have been several studies about the election results, but most of them have been done without much quantitative analyses. This study examines voting patterns of Fiji’s 2018 election by provinces, and rural-urban localities, as well as by candidates, and also compares the 2018 and 2014 elections by spending a substantial time classifying officially released data by polling stations and individual candidates. Some of the data are then further aggregated according to the political parties to which those candidates belonged. The current electoral system in Fiji is a version of a proportional system, but its use is rare and this study will provide an interesting case study of the Open List Proportional System. At the end of the analyses, this study considers possible reasons for the swing in favour of the Opposition.


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