scholarly journals DHATUROOPI SHUKRA AND BEEJAROOPI SHUKRA: A CRITICAL REVIEW

2022 ◽  
Vol 12 (6) ◽  
pp. 84-88
Author(s):  
Anand G. Keriyawar ◽  
Mohammad Ashraf D. Samudri ◽  
Raghavendra V. Shettar
Keyword(s):  
Bone Marrow ◽  
Cell Division ◽  
Human Body ◽  
Skin Disease ◽  
Tissue Growth ◽  
Entire Body ◽  
Meiotic Cell ◽  
Regenerative Capacity ◽  
The One ◽  
Equal Contribution

Shukra is studied in Ayurveda both as a dhatu and beeja. As a mammalian human body comprises both somatic and gonadal cells. Somatic cells help for growth and regeneration through mitosis. Meiotic cell division causes equal contribution for the inheritance from maternal and paternal sides. Beejartham (reproduction) is the supreme function attributed to Shukra. Reproduction refers to the formation of new cells for tissue growth, repair/replacement (sukshmavayavantarotpatti), or the production of a new individual (shareerantarotpatti). Regenerative capacity is distributed unequally among species, individuals, and tissues. The affliction of shukrastana by kusthadosha (skin disease) causes a failure in regeneration. The affliction of parents' shukra and artava (gametes) by kusthadosha (skin disease) inherits to the next generation. Vrushan (testis) and medru (penis) are the moola of the shukravahavaha srotus, which is meant to fertilise the ovum (beejarupishukra). Majja (bone marrow) and stana (breasts) are the moola of the shukravaha srotus of the one pervading the entire body (dhaturupishukra).

scholarly journals A PHYSIOLOGICAL STUDY OF SHUKRA DHATU W.S.R. SEXUAL HORMONES

2021 ◽  
Vol 9 (9) ◽  
pp. 2165-2173
Author(s):  
Prakash Choudhary ◽  
Rajesh Kumar Sharma ◽  
Dinesh Chandra Sharma ◽  
Mukesh Saini
Keyword(s):  
Germ Cell ◽  
Human Body ◽  
Primordial Germ Cell ◽  
Good Health ◽  
The Body ◽  
Entire Body ◽  
Sexual Hormones ◽  
Male Sex ◽  
The One ◽  
Definite Role

Ayurveda has described three basic physiological constituents of the human body, viz., Dosha, Dhatu and Mala. In Ayurvedic Science, the one who has balanced Doshas, balanced Agni, properly formed Dhatus, proper elimina- tion of Malas, well-functioning of bodily processes and whose mind, soul, senses are full of bliss is called a healthy person1. So, the formation of Dhatu is also a good indicator of good health there are seven Dhatus ex- plained in Samhitas, those are Rasa, Rakta, Mamsa, Meda, Ashti, Majja and Shukra among all Dhatus, Shukra is considered as the sara of all other Dhatus2. Shukra Dhatu is one of the seven Dhatus in the body and Shukra is white, pure, excellent Dhatu, which is considered as best among all seven Dhatus. According to many Acharyas of Ayurveda, Garbhotpadana (reproduction) is the chief function of Shukra Dhatu, and the important fact is Shukra Dhatu also shows its effect all over the body in the form of Shukradhatusarata because Shukradhatuis located in the entire body. Sperm along with spermatic fluid and male sex hormones are also one part of Shukra Dhatu. Anu Shukra Dhatu (primordial germ cell) is essential for the Shukra Dhatu (Testosterone, Estrogen). Vi- tiation of Shukra dhatu shows Shukra dhatudusti (pathology) in the form of Vriddhi (hyper state) or Kshaya (wan- ing). This vitiation may lead to main infertility and many other physical as well as psychological disorders. All Dhatus have their definite locations in the body; they are present in every cell in subtle form. Every cell possesses the capacity to divide or reproduce itself. Thus, one has to interpret the Garbhotpadana (reproduction) function of Shukra Dhatu. In future, it may be achievable that with the development of the facts; we will discover any content in the cell whichpossesses a definite role in cell division.Sperms along with spermatic fluid and male sex hor- mones are also one Partofshukra, parallel to which females possess Artava. Stri-Shukra excreted during coitus is nothing but the secretions of bartholins, cervical and endometrial glands emergence at theendoforgasm. Keywords:Ayurveda, Stree-Shukra, Shukra Dhatu, Artava, hormones.

scholarly journals Studies on the Antimitotic Activity of Leurocristine (Vincristine)

Blood ◽  
1963 ◽  
Vol 21 (1) ◽  
pp. 102-110 ◽  
Author(s):  
GIUSEPPE CARDINALI ◽  
GIULIANA CARDINALI ◽  
MOSTAFA ABOUL ENEIN
Keyword(s):  
Bone Marrow ◽  
Cell Division ◽  
Leukemic Cells ◽  
Normal Bone Marrow ◽  
L1210 Leukemia ◽  
Normal Bone ◽  
Antimitotic Activity ◽  
Metaphase Stage ◽  
The One

Abstract The effect of leurocristine (vincristine) on cell division was studied in normal bone marrow and leukemic cells (L1210 leukemia) of DBA/2 mice. It was found that vincristine possesses the ability to arrest mitosis at the metaphase stage. The accumulation of arrested metaphases in the normal bone marrow and in leukemic cells of the animals treated with vincristine followed a pattern similar to the one observed after treatment with colchicine or vincaleukoblastine (vinblastine).

3036 – BONE MARROW TRANSPLANTATION COMPROMISES THE REGENERATIVE CAPACITY OF THE BONE MARROW NICHE

2020 ◽  
Vol 88 ◽  
pp. S49
Author(s):  
Theresa Sippenauer ◽  
J. Geuder ◽  
J. Hecker ◽  
F. Hettler ◽  
S. Romero-Marquez ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Bone Marrow Niche ◽  
Regenerative Capacity

scholarly journals The Impact of Tick-Borne Diseases on the Bone

2021 ◽  
Vol 9 (3) ◽  
pp. 663
Author(s):  
Imran Farooq ◽  
Tara J. Moriarty
Keyword(s):  
Bone Marrow ◽  
Lyme Disease ◽  
Bone Loss ◽  
Human Body ◽  
Virus Disease ◽  
Hemorrhagic Fever ◽  
Research Literature ◽  
Tick Borne Encephalitis ◽  
Bone Marrow Function ◽  
The Impact

Tick-borne infectious diseases can affect many tissues and organs including bone, one of the most multifunctional structures in the human body. There is a scarcity of data regarding the impact of tick-borne pathogens on bone. The aim of this review was to survey existing research literature on this topic. The search was performed using PubMed and Google Scholar search engines. From our search, we were able to find evidence of eight tick-borne diseases (Anaplasmosis, Ehrlichiosis, Babesiosis, Lyme disease, Bourbon virus disease, Colorado tick fever disease, Tick-borne encephalitis, and Crimean–Congo hemorrhagic fever) affecting the bone. Pathological bone effects most commonly associated with tick-borne infections were disruption of bone marrow function and bone loss. Most research to date on the effects of tick-borne pathogen infections on bone has been quite preliminary. Further investigation of this topic is warranted.

scholarly journals Ciliary protein conservation during development in the ciliated protozoan, Oxytricha.

1987 ◽  
Vol 105 (6) ◽  
pp. 2855-2859 ◽  
Author(s):  
G W Grimes ◽  
R H Gavin
Keyword(s):  
Cell Division ◽  
Daughter Cell ◽  
Basal Bodies ◽  
Ciliated Protozoan ◽  
Subunit Exchange ◽  
Electrophoretic Data ◽  
Autoradiographic Analysis ◽  
Protein Conservation ◽  
The One ◽  
Molecular Conservation

The ciliated protozoan Oxytricha fallax possesses multiple highly localized clusters of basal bodies and cilia, all of which are broken down and rebuilt during prefission morphogenesis-with one major exception. The adoral zone of membranelles (AZM) of the ciliate oral apparatus contains approximately 1,500-2,000 basal bodies and cilia, and it is the only compound ciliary structure that is passed morphologically intact to one daughter cell at each cell division. By labeling all proteins in cells, and then picking the one daughter cell possessing the original labeled AZM, we could then evaluate whether or not the ciliary proteins of the AZM were diluted (i.e., either by degradation to constituent amino acids or by subunit exchange) during cell division. Autoradiographic analysis demonstrated that the label was highly conserved in the AZM (i.e., we saw no evidence of turnover), and electrophoretic data illustrate that at least one of the proteins of the AZM is tubulin. We, therefore, conclude that for at least some of the ciliary and basal body proteins of Oxytricha fallax, AZM morphological conservation is essentially equivalent to molecular conservation.

scholarly journals Midbody: From the Regulator of Cytokinesis to Postmitotic Signaling Organelle

Medicina ◽  
2018 ◽  
Vol 54 (4) ◽  
pp. 53 ◽  
Author(s):  
Ieva Antanavičiūtė ◽  
Paulius Gibieža ◽  
Rytis Prekeris ◽  
Vytenis Skeberdis
Keyword(s):  
Stem Cells ◽  
Cell Division ◽  
Intercellular Bridge ◽  
Large Protein ◽  
Daughter Cells ◽  
First Case ◽  
Tumorigenic Potential ◽  
The One ◽  
And Function ◽  
Protein Rich

Faithful cell division is crucial for successful proliferation, differentiation, and development of cells, tissue homeostasis, and preservation of genomic integrity. Cytokinesis is a terminal stage of cell division, leaving two genetically identical daughter cells connected by an intercellular bridge (ICB) containing the midbody (MB), a large protein-rich organelle, in the middle. Cell division may result in asymmetric or symmetric abscission of the ICB. In the first case, the ICB is severed on the one side of the MB, and the MB is inherited by the opposite daughter cell. In the second case, the MB is cut from both sides, expelled into the extracellular space, and later it can be engulfed by surrounding cells. Cells with lower autophagic activity, such as stem cells and cancer stem cells, are inclined to accumulate MBs. Inherited MBs affect cell polarity, modulate intra- and intercellular communication, enhance pluripotency of stem cells, and increase tumorigenic potential of cancer cells. In this review, we briefly summarize the latest knowledge on MB formation, inheritance, degradation, and function, and in addition, present and discuss our recent findings on the electrical and chemical communication of cells connected through the MB-containing ICB.

Bodily Dasein and Chinese Script Components

2017 ◽  
Vol 2017 (2) ◽  
Author(s):  
Kwan Tze-wan
Keyword(s):  
Human Body ◽  
The Body ◽  
Chinese Script ◽  
Chinese Characters ◽  
Body Parts ◽  
Constitutive Principle ◽  
New Perspective ◽  
Social Environmental ◽  
The One ◽  
Definition Of

AbstractIn the Shuowen, one of the earliest comprehensive character dictionaries of ancient China, when discussing where the Chinese characters derive their structural components, Xu Shen proposed the dual constitutive principle of “adopting proximally from the human body, and distally from things around.” This dual emphasis of “body” and “things around” corresponds largely to the phenomenological issues of body or corporeality on the one hand, and lifeworld on the other. If we borrow Heidegger’s definition of Dasein as Being-in-the world, we can easily arrive at a reformulation of Xu Shen’s constitutive principle of the Chinese script as one that concerns “bodily Dasein.” By looking into various examples of script tokens we can further elaborate on how the Chinese make use not only of the body in general but various body parts, and how they differentiate their life world into material nature, living things, and a multifaceted world of equipment in forming a core basis of Chinese characters/components, upon which further symbolic manipulation such as “indication”, “phonetic borrowing”, semantic combination, and “annotative derivation”, etc. can be based. Finally, examples will be cited to show how in the Chinese scripts the human body (and its parts) might interact with other’s bodies (and their parts) or with “things around” (whether nature, living creatures, or artifacts) in various ways to cover the social, environmental, ritual, technical, economical, and even intellectual aspects of human experience. Bodily Dasein, so to speak, provides us with a new perspective of understanding and appreciating the entire scope of the Chinese script.

scholarly journals Polyclonal hematopoiesis in interferon-induced cytogenetic remissions of chronic myelogenous leukemia

Blood ◽  
1992 ◽  
Vol 79 (4) ◽  
pp. 997-1002 ◽  
Author(s):  
D Claxton ◽  
A Deisseroth ◽  
M Talpaz ◽  
C Reading ◽  
H Kantarjian ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Gene Polymorphism ◽  
Chronic Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Hematopoietic Stem ◽  
Clonality Analysis ◽  
Ifn Therapy ◽  
Cytogenetic Remission ◽  
The One

Interferon (IFN) therapy of early chronic myelogenous leukemia (CML) frequently produces partial or complete cytogenetic remission of the disease. Patients with complete cytogenetic remission often continue on therapy for several years with bone marrow showing only diploid (normal) metaphases. We studied hematopoiesis in five female patients with major cytogenetic remissions from CML during IFN therapy. Clonality analysis using the BstXI PGK gene polymorphism showed that granulocytes were nonclonal in all patients during cytogenetic remission. BCR region studies showed rearrangement only in the one patient whose remission was incomplete at the time of sampling. Granulopoiesis is nonclonal in IFN-induced remissions of CML and may be derived from normal hematopoietic stem cells.

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