scholarly journals Bactericidal Potential of Local Medicinal Plants of Kashmir Valley in Fishes: A Review

2021 ◽  
pp. 21-27
Author(s):  
Inain Jaies ◽  
Feroz Ahmad Shah ◽  
Shabir Ahmad Dar ◽  
Syed Shariq Nazir Qadiri ◽  
Asifa Wali ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Bacterial Infections ◽  
Antibacterial Activities ◽  
Significant Loss ◽  
Human Consumption ◽  
Kashmir Valley ◽  
Antibacterial Drugs ◽  
Bacterial Diseases ◽  
Natural Herb

Bacterial diseases in fishes create one of the alarming situations that render significant loss to the fishing industries and aquacultural farm units worldwide. Various drugs have been formulated, standardized, and used in the industry to combat bacterial infections. However, non-judicious drugs can lead to pharmacological problems and induction of toxicity in fishes, leaving them less suitable for human consumption. These drugs can be supplemented with the natural herb plants having antibacterial activities, although they cannot be used solely to curb the menace. Therefore, the review put forth an idea, which plant herbs can be used as antibacterial drugs in fishes.

scholarly journals Antibacterial Activities of Selected Cameroonian Plants and Their Synergistic Effects with Antibiotics against Bacteria Expressing MDR Phenotypes

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Stephen T. Lacmata ◽  
Victor Kuete ◽  
Jean P. Dzoyem ◽  
Simplice B. Tankeo ◽  
Gerald Ngo Teke ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Bacterial Infections ◽  
Synergistic Effects ◽  
Antibacterial Properties ◽  
Efflux Pumps ◽  
Antibacterial Activities ◽  
Garcinia Kola ◽  
Active Efflux ◽  
Minimal Inhibitory Concentrations ◽  
Methanol Extracts

The present work was designed to assess the antibacterial properties of the methanol extracts of some Cameroonian medicinal plants and the effect of their associations with currently used antibiotics on multidrug resistant (MDR) Gram-negative bacteria overexpressing active efflux pumps. The antibacterial activities of twelve methanol extracts of medicinal plants were evaluated using broth microdilution. The results of this test showed that three extractsGarcinia lucidawith the minimal inhibitory concentrations (MIC) varying from 128 to 512 μg/mL,Garcinia kola(MIC of 256 to 1024 μg/mL), andPicralima nitida(MIC of 128 to 1024 μg/mL) were active on all the twenty-nine studied bacteria including MDR phenotypes. The association of phenylalanine arginineβ-naphthylamide (PAβN or efflux pumps inhibitor) to different extracts did not modify their activities. At the concentration of MIC/2 and MIC/5, the extracts ofP. nitidaandG. kolaimproved the antibacterial activities of some commonly used antibiotics suggesting their synergistic effects with the tested antibiotics. The results of this study suggest that the tested plant extracts and mostly those fromP. nitida,G. lucidaandG. kolacould be used alone or in association with common antibiotics in the fight of bacterial infections involving MDR strains.

scholarly journals A review: antimicrobial properties of several medicinal plants widely used in Traditional Chinese Medicine

2021 ◽  
Vol 5 ◽  
Author(s):  
Kun Chen ◽  
Wei Wu ◽  
Xiudan Hou ◽  
Qingli Yang ◽  
Zhaojie Li
Keyword(s):  
Medicinal Plants ◽  
Bacterial Resistance ◽  
Synergistic Effects ◽  
Antimicrobial Properties ◽  
Antibacterial Activities ◽  
Extraction Methods ◽  
In Vitro Assays ◽  
Antibacterial Drugs ◽  
Antibacterial Compounds

Abstract Due to the dramatic increase in the use of antibiotics and growing health threat of bacterial resistance to many commonly used antibiotics, many studies have been directed at developing new and effective antibacterial compounds, among which many new, natural, and effective antibacterial compounds discovered from medicinal plants have drawn great interest and raised new hope for treating the challenges of antibiotic resistance. This review aimed to summarize the most important and widely used medicinal plants that were reported to have antibacterial activities. A general literature search from 2010 to 2020 was conducted using different databases, including Science Direct, Web of Science, and PubMed. According to the literature, three medicinal plants with outstanding antibacterial activities, Taraxacum officinale, Coptis Rhizome, and Scutellaria baicalensis, were screened and reviewed by prioritization. The extraction methods, antibacterial activities of different parts of plants or the plant-derived compounds, spectra of antibacterial activities, and toxicity were described, respectively. However, the antibacterial activities of the extracts or pure compounds as reported in the reviewed literature were mostly based on in vitro assays, and moreover, the deeper antibacterial mechanisms have not been elucidated clearly. Therefore, further studies are required in the fields of purification and identification of the antibacterial compounds, its mechanisms of action, and synergistic effects in combination with other antibacterial drugs, which may be helpful in the development of new antibacterial drugs.

Medicinal Plants: Antibacterial Effects and Chemical Composition of Essential Oil of Foeniculum vulgare

2017 ◽  
Vol 8 (01) ◽  
Author(s):  
Azadeh Foroughi ◽  
Pouya Pournaghi ◽  
Fariba Najafi ◽  
Akram Zangeneh ◽  
Mohammad Mahdi Zangeneh ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Medicinal Plants ◽  
Essential Oil ◽  
Antibacterial Properties ◽  
Screen Test ◽  
Antibacterial Activities ◽  
Gas Chromatography Mass Spectrometry ◽  
Resistant Bacteria ◽  
Antibacterial Effects ◽  
Foeniculum Vulgare

Medicinal plants are considered modern resources for producing agents that could act as alternatives to antibiotics in demeanor of antibiotic-resistant bacteria. The aim of the study was to evaluate the chemical composition and antibacterial activities of essential oil of Foeniculum vulgare (FV) against Pseudomonas aeruginosa and Bacillus subtilis. Gas chromatography mass spectrometry was done to specify chemical composion. As a screen test to detect antibacterial properties of the essential oil, agar disk and agar well diffusion methods were employed. Macrobroth tube test was performed to determinate MIC. The results indicated that the most substance found in FV essential oil was Trans-anethole (47.41 %), also the essential oil of FV with 0.007 g/ml concentration has prevented P. aeruginosa and with 0.002 g/ml concentration has prevented B. subtilis from the growth. Thus, the research represents the antibacterial effects of the medical herb on test P. aeruginosa and B. subtilis. We believe that the article provide support to the antibacterial properties of the essential oil. The results indicate the fact that the essential oil from the plant can be useful as medicinal or preservatives composition.

scholarly journals Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection

Microbiome ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Andre Mu ◽  
Daniel McDonald ◽  
Alan K. Jarmusch ◽  
Cameron Martino ◽  
Caitriona Brennan ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Phage Therapy ◽  
Ecological Impacts ◽  
Skin Microbiome ◽  
Bacteriophage Therapy ◽  
Bacterial Diseases ◽  
Device Infection ◽  
Global Health Issue ◽  
Serious Bacterial Infections ◽  
Systemic Antibiotics

Abstract Background Infectious bacterial diseases exhibiting increasing resistance to antibiotics are a serious global health issue. Bacteriophage therapy is an anti-microbial alternative to treat patients with serious bacterial infections. However, the impacts to the host microbiome in response to clinical use of phage therapy are not well understood. Results Our paper demonstrates a largely unchanged microbiota profile during 4 weeks of phage therapy when added to systemic antibiotics in a single patient with Staphylococcus aureus device infection. Metabolomic analyses suggest potential indirect cascading ecological impacts to the host (skin) microbiome. We did not detect genomes of the three phages used to treat the patient in metagenomic samples taken from saliva, stool, and skin; however, phages were detected using endpoint-PCR in patient serum. Conclusion Results from our proof-of-principal study supports the use of bacteriophages as a microbiome-sparing approach to treat bacterial infections.

A review of medicinal plants used in the Brazilian Cerrado for the treatment of fungal and bacterial infections

2021 ◽  
pp. 100523
Author(s):  
Jhonatas Emílio Ribeiro da Cruz ◽  
Hellyssa Cataryna Saldanha ◽  
Guilherme Ramos Oliveira e Freitas ◽  
Enyara Rezende Morais
Keyword(s):  
Medicinal Plants ◽  
Bacterial Infections ◽  
Brazilian Cerrado

scholarly journals In VitroAntistaphylococcal Effects ofEmbelia schimperiExtracts and Their Component Embelin with Oxacillin and Tetracycline

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Johana Rondevaldova ◽  
Olga Leuner ◽  
Alemtshay Teka ◽  
Ermias Lulekal ◽  
Jaroslav Havlik ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Medicinal Plants ◽  
Bacterial Infections ◽  
Inhibitory Concentration ◽  
Developed Countries ◽  
Positive Interactions ◽  
Fractional Inhibitory Concentration ◽  
Broth Microdilution ◽  
Microdilution Method ◽  
Broth Microdilution Method

Bacterial infections are in less-developed countries traditionally treated by remedies prepared from medicinal plants.Embelia schimperi(Vatke) is a plant used as a taenicide or disinfectant in Ethiopia, very often taken mixed with another plant species. In the present study, we examined two extracts prepared from seeds and twigs with leaves ofE. schimperiand its main present secondary metabolite embelin for their antibacterial combinatory effect with oxacillin and tetracycline against sensitive and resistantStaphylococcus aureusstrains. Minimum inhibitory concentrations were determined through the broth microdilution method, whereas the combinatory effect was evaluated through fractional inhibitory concentration sum (ΣFIC) indices. Results show many positive interactions and synergy occurring in embelin and oxacillin combinations against 4 out of 9 strains (ΣFIC 0.203–0.477) and for embelin and tetracycline combination against 3 out of 9 strains (ΣFIC 0.400–0.496). Moreover, the resistance to oxacillin has been overcome in 2 strains and to tetracycline in 3 strains. According to our knowledge, this is the first study showing antimicrobial combinatory effect ofE. schimperias well as of embelin. These findings can be used for the further research targeted on the development of new antistaphylococcal agents.

scholarly journals ЧУТЛИВІСТЬ ЗБУДНИКІВ БАКТЕРІАЛЬНИХ ХВОРОБ ПТИЦІ ДО АНТИБАКТЕРІАЛЬНИХ ПРЕПАРАТІВ

2016 ◽  
Vol 18 (3(71)) ◽  
pp. 182-185
Author(s):  
A.A. Fotina ◽  
Zh.E. Klischova
Keyword(s):  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Age Groups ◽  
Economic Loss ◽  
Diffusion Method ◽  
Antimicrobial Drugs ◽  
Bacterial Diseases ◽  
Test Systems ◽  
Poultry Farms ◽  
Pathological Material

The using of antibiotics and antimicrobials drugs without control may leads to the development of numerous complications and resistance of microorganisms to antibiotics. The using of antibiotics and antimicrobials drugs should are controlled on poultry farms. That is why the monitoring and determination of sensitivity of bacterial diseases agents to antimicrobial drugs are very important. Results of salmonellas’ and kolibakterias’ monitoring in poultry’s farms of Ukraine are introduced in the article. Researches were conducted at the Department of veterinary sanitary examination, microbiology, zoohygiene and safety and quality of livestock products of Sumy NAU. Sampling for microbiological studies was conducted from the hatchery and from pathological material and premises where poultry of different age groups was held. The spread of the disease, morbidity, mortality, mortality rate, age characteristics, economic loss what diseases cause to the poultry farms were counted. Identification of Salmonella and Escherichia was conducted by ELISA with using of RIDASCREEN® and LOCATE® test systems, according to methodical recommendations of RIDASCREEN® and LOCATE® test systems using. The results were read visually or after addition of storageco with ELISA–photometer (reader) at 450 nm. Sensitivity to antibiotics was determined by disco – diffusion method in agar. Microbiological monitoring of a number of poultry farms in Ukraine has shown that agents of bacterial diseases’ are widely spread. Between the isolated microflora largest number were accounted for Salmonella (54.1%) and the Escherichia (30.8 per cent). The rest (15,1%) were isolated cultures of Proteus, Pseudomonas, Klebsiella, Salmonella, Campylobacteria, Enterobacteria, and Clostridia Citrobacter. This indicates that systematic control over the availability of the causative agents of bacterial infections in all critical points of production of poultry products is very necessary. Among isolates that were isolated from ill poultry and poultry objects, differences in their sensitivity to antimicrobial agents from active substances that officially have registered in our country were discovered. Bactericidal activity of relatively isolated cultures was showed by colistin, ftorfenicol, zeftiocur, TimTil 250, doxicyclin, enroxil and sarafloxacin.  

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