scholarly journals Evaluation of Platelet Counts in the Normal Pregnancy and other Gestational Conditions at Tertiary Care Hospital of Sindh

2021 ◽  
pp. 106-111
Author(s):  
. Palwasha ◽  
Kanwal Abbas Bhatti ◽  
Fahmida Gul ◽  
Sameena Gul Memon ◽  
Pashmina Shaikh
Keyword(s):  
Platelet Count ◽  
Tertiary Care Hospital ◽  
Gestational Hypertension ◽  
Tertiary Care ◽  
Normal Pregnancy ◽  
Major Theme ◽  
Care Hospital ◽  
Hepatic Disorder ◽  
Platelet Counts ◽  
Proper Management

Background: During gestational period, the most common disorder is hypertension that directly affects the gestation. The frequency of gestational hypertension is increasing day by day and ultimately the pressure is developed on the endothelial wall. Gestational hypertension mostly reduces the platelet counts. Aim of Study: The major theme of this research is evaluating the count of platelet during pregnancy and other gestational conditions. Methodology: A Retrospective research was carried out for the period of 06 months at Gynae and Obstetrics ward at tertiary care hospital of Sindh, Pakistan. Total 104 females were selected with different gestational age and trimester. A questionnaire was filled by all participants that were comprised of demographic data and gestational conditions such as preeclampsia, eclampsia, parity and seizure episodes. Females with highest risk factors diseases such as Diabetes, Hepatic disorder, Anemia, renal disorder and cardio vascular disease were not included in our research. Blood samples were collected from all selected participants for proper platelet count and data was compared with normal ranges of platelet count among the pregnant females. Data was analyzed by using statistical software 24.00 versions. Results: It was observed that 49 patients were having normal pregnancy, 32 had preeclampsia and 23 had eclampsia. 38 participants were first timer & 52 were having second time parity. 58 participants had 2nd trimester of pregnancy. According to condition of anemia, 27 had severe anemic condition whereas 43 had moderate anemic condition. 49 participants had reduced level of platelet count and 17 had very low platelet count. Severity of gestation can be managed through proper management and physician instructions. Hypertension was measured through severity scale, 29 patients had moderate level of hypertension and 22 had severe level of hypertension. 19 participants had very abnormal level of blood count. Conclusion: It was concluded that proper diagnostic test should be conducted on time for proper management of reduced platelet count and there should be proper mass counseling should be conducted in order to overcome the deficiency of platelet count. There should be proper diet and exercise during pregnancy that can manage the condition of hypertension.  Severity of gestation can be managed through proper management and physician instructions.

scholarly journals To Evaluate the Frequency of Diabetes Mellitus Patients with Hepatitis C at Tertiary Hospital of Sindh, Pakistan

2021 ◽  
pp. 34-38
Author(s):  
Kuldeep Kumar Mewaram ◽  
Faraz Qurban Rajper ◽  
Khalida Unar ◽  
Mirza Tasawar Baig ◽  
Mirza Tasawar Baig ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hepatitis C ◽  
Nucleic Acid ◽  
Sample Size ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Major Theme ◽  
Care Hospital ◽  
Age Group

Objective: The major theme of the research was to evaluate the frequency of diabetes mellitus patients with hepatitis C infection at tertiary care hospital of Sindh, Pakistan. Methodology: Descriptive cross sectional study was conducted at tertiary care hospital of Sindh, Pakistan for the period of 08 months; total 374 sample size was calculated by using Rao soft sample size calculator at the prevalence rate of 58.3% and confidence level 95% and margin of error 5%. Data was collected from patients of sero-positive HCV-RNA (Hepatitis C Virus-Ribose Nucleic Acid) visiting outpatient department or admitted at tertiary care hospital of Sindh, Pakistan and Informed consent form was also filled from all included subjects and data was analyzed by using SPSS software version 24.00. Results: From the 374 patients 209 were males and 165 females and all participants were divided in to various age groups as 15 patients were in the age group of 20-25 years, 67 patients were in 26-30 years, 48 patients included in 31-35 years and 109 patients were included in to age group of 36-40 years. Only 12 patients were included in the age group of 50 years and above. Total 164 (43.85%) were diabetic and 229 (61.22%) were diagnosed with Hepatitis C RNA (Ribose Nucleic Acid) positive. Patients had various range of HbA1c as 93 patients had range between 6-7mmol/dl. 107(28.60%) included in 7-9mmol/dl, 145(38.77%) included in 9-11mmol/dl and only 29 patients were having HbA1c (Glycated Hemoglobin) level above 11mmol/dl. Conclusion: It was concluded that there were increased number of diabetic patients with hepatitis C in worsening condition, so the proper programs should be conducted in order to reduce the complication of co-morbid disease.

scholarly journals Prevalence of Hemolysis, Elevated Liver Enzymes, Low Platelet Count Syndrome in Pregnant Women in a Tertiary Care Hospital

2020 ◽  
Vol 58 (226) ◽  
Author(s):  
Sarita Sitaula ◽  
Tara Manandhar ◽  
Baburam Dixit Thapa ◽  
Ramesh Shrestha ◽  
Dinesh Dharel
Keyword(s):  
Platelet Count ◽  
Confidence Interval ◽  
Liver Enzymes ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Perinatal Morbidity ◽  
Elevated Liver Enzymes ◽  
Low Platelet Count

Introduction: Hemolysis, Elevated Liver Enzymes, Low Platelet count syndrome refers to biological syndrome occurring in pre-eclamptic and eclamptic women. There is a higher rate of maternal and perinatal morbidity and mortality due to the syndrome. So, the objective of the study is to find the prevalence and maternal- perinatal outcome in the syndrome. Methods: A descriptive cross-sectional study was done in a tertiary care hospital from 1st April 2017 to 30th March 2018 after obtaining ethical clearance from the Institutional Review Committee. The inclusion criteria were patients giving consent for participation and those who delivered in our hospital. Patient with the syndrome who delivered outside and referred in the postpartum period was excluded because details of the neonate may not be available. The Statistical Package for Social Sciences version 21 was used for the analysis of the data. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 11974 deliveries, the prevalence of Hemolysis, Elevated Liver Enzymes, Low Platelet count syndrome was 83 (0.69%) at 95% Confidence Interval (59.06-78.94). Maternal complications were seen in 19 (22.9%) and common complications being acute renal failure 9 (47.37%) followed by postpartum hemorrhage 4 (21.05%). Nearly 27 (33%) of patients required maternal ICU stay and there was one maternal mortality. Conclusions: Hemolysis, Elevated Liver Enzymes, Low Platelet count syndrome is one of the major causes of maternal and perinatal morbidity and mortality. Hence early recognition and prompt management may improve maternal and fetal outcomes.

ASSOCIATION THROMBOCYTOPENIAAND ITS CO-RELATION IN CHRONIC LIVER DISEASE PATIENTS IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 24-26
Author(s):  
Subhashis Chakraborty ◽  
Debarshi Jana
Keyword(s):  
Platelet Count ◽  
Liver Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
General Medicine ◽  
Severe Thrombocytopenia ◽  
Care Hospital ◽  
Underlying Liver Disease ◽  
Number Of Factors ◽  
One Year

INTRODUCTION: The prevalence of thrombocytopenia varies according to a number of factors, like patient population and severity of underlying liver disease. AIMS AND OBJECTIVES: To determine prevalence of thrombocytopenia in CLD patients and correlation of platelet count with child and pugh scores. MATERIALAND METHOD: General Medicine ward and OPD of N.R.S.M.C.H. , Kolkata, All patients admitted with CLD in Medicine ward and those attending OPD of N.R.S.M.C.H. , Kolkata, One year, 101 (one hundred and one) CONCLUSION: We found that mean Platelet count was low in Severe Thrombocytopenia which was statistically signicant.

scholarly journals Frequency of Thrombocytopenia in Neonates Following Phototherapy in Neonatology Unit of Tertiary Care Hospital

2021 ◽  
pp. 252-257
Author(s):  
Hina Naqvi ◽  
Shazia Memon ◽  
Mushtaque Ali Shah ◽  
Muhammad Nadeem Chohan ◽  
Numra Shaikh ◽  
...  
Keyword(s):  
Platelet Count ◽  
Complete Blood Count ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
University Hospital ◽  
Total Serum ◽  
Care Hospital ◽  
Baseline Platelet Count ◽  
Paediatric Department ◽  
Neonatal Ward

Aim: To determine the frequency of thrombocytopenia and its severity in relation to level of indirect hyperbilirubinemia in neonates following phototherapy at tertiary care hospital. Study Design: Descriptive study Place and duration:  This study was conducted at Paediatric department (neonatal ward), Liaquat University Hospital, Hyderabad, from 1st August 2020 till 31st Jan 2021 Methodology: All neonates who fulfilled the inclusion criteria presented at pediatric department (neonatal ward), Liaquat University Hospital Hyderabad were included in the study. After written consent, brief history was taken from the mother or family member and complete blood count (CBC) was sent to check the baseline platelet count along with total serum bilirubin, it was repeated after 48 hours of phototherapy. Results: Out of 231 neonates 70 (30.3%) developed thrombocytopenia after phototherapy. In our study 117 neonates (50.6%) were males & 114 neonates (49.4%) were females with the mean age of 5.9307+1.6640 days. The thrombocytopenia was seen in 70 neonates (30.3%) and type of severity was mild, moderate & severe in 52(22.5%), 13(5.6%) & 5(2.2%) respectively. Conclusion: There was a decline in mean platelet count after phototherapy but it was not statistically significant. The treating doctor should also keep in mind, other causes of thrombocytopenia when the patient is receiving phototherapy.

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