scholarly journals Comparitive Study of Formulated Herbal Mosquito Repellent Incense Sticks with Market Product

2021 ◽  
pp. 128-132
Author(s):  
S. Valarmathi ◽  
M. Senthil Kumar ◽  
. Chithra ◽  
. Coralinanisha ◽  
Antony nelson Prabhu ◽  
...  
Keyword(s):  
Allergic Reactions ◽  
Vitex Negundo ◽  
Mosquito Repellent ◽  
Respiratory Disorders ◽  
Market Product ◽  
Mosquito Repellents ◽  
Holy Basil

The mosquito repellent formulations that are available on the market are causing irritations like coughing, sneezing, allergic reactions and respiratory disorders to human.The mosquito repellents available in the market are in various forms like colis,mats,sprays and fast cards. So the present study was carried out to formulate mosquito repellent incense sticks using herbals like Vitex negundo, Neem, Holy basil, and Garlic. The poly herbal mosquito repellent formulation are made by hand rolling method.The solid formulation containing binders and additives are rolled in the form of incense sticks and dried for 24 hrs. After drying its evaluated and compared with the market formulation. The prepared herbal mosquito incense sticks are potent, safe with more duration of time and less cost.

Development and Evaluation of Herbal Mosquito Repellent Cream

2021 ◽  
pp. 6262-6268
Author(s):  
Bapan Banik ◽  
Jayanta Barman ◽  
Manash Pratim Dutta ◽  
Nikita Bhowmick
Keyword(s):  
Repellent Activity ◽  
Cross Resistance ◽  
Allergic Reactions ◽  
Vitex Negundo ◽  
Mosquito Repellent ◽  
Leaf Extracts ◽  
Development Of Resistance ◽  
Different Types ◽  
Safe Product

Mosquito repellent is a product that is applied to the skin or other surfaces to deter insects (and arthropods in general) from landing or climbing on that surface. The interest in plant-based repellants has been revived seeing that the development of resistance, cross-resistance and possible toxicity hazards associated with synthetic insecticides and their rising cost. The present study aimed towards the development and evaluation of safe and efficient herbal mosquito repellent from leaf extracts of Azadirachta indica, Vitex negundo, and Ocimum gratissimum. Six different types of formulation (Type-1 to 6) were prepared using each plant extract and optimized ingredients. The mosquito repellent activity of the formulation was tested using the arm-in-cage method. One skin rubbed with a small quantity of formulation was exposed to 20 mosquitoes and the number of mosquitoes that aligned or biting the arm was recorded in each minute for five minutes. The most effective repellent activity of the Type2 formulation was 87.5% (Y-shaped Model) and 91.62% (Rectangular-shaped Model). The Type1, Type3, Type4, Type5 and Type6 formulation showed 66.62% , 58.25%, 68.75%, 70.75% and 62.5% repellent activity in Y shaped model and 66.62%, 62.5%, 70.75%, 83.25% and 62.5% repellent activity in Rectangular shaped model respectively. During these studies, we found that Hexane extract showed higher repellent activity. No allergic reactions were observed upon the skin. So, it is a safe product. The formulation was ecological, economical and highly efficient.

Computational Approaches for the Design of Mosquito Repellent Chemicals

2020 ◽  
Vol 27 (1) ◽  
pp. 32-41 ◽  
Author(s):  
Subhash C. Basak ◽  
Apurba K. Bhattacharjee
Keyword(s):  
Computational Design ◽  
Quantitative Structure Activity Relationship ◽  
Computer Assisted ◽  
Quantitative Structure ◽  
Mosquito Repellent ◽  
Computational Approaches ◽  
Qsar Studies ◽  
Computer Assisted Design ◽  
Structure Activity ◽  
Mosquito Repellents

Background: In view of many current mosquito-borne diseases there is a need for the design of novel repellents. Objective: The objective of this article is to review the results of the researches carried out by the authors in the computer-assisted design of novel mosquito repellents. Methods: Two methods in the computational design of repellents have been discussed: a) Quantitative Structure Activity Relationship (QSAR) studies from a set of repellents structurally related to DEET using computed mathematical descriptors, and b) Pharmacophore based modeling for design and discovery of novel repellent compounds including virtual screening of compound databases and synthesis of novel analogues. Results: Effective QSARs could be developed using mathematical structural descriptors. The pharmacophore based method is an effective tool for the discovery of new repellent molecules. Conclusion: Results reviewed in this article show that both QSAR and pharmacophore based methods can be used to design novel repellent molecules.

pHEMA hydrogels with pendant triazinyl-β-cyclodextrin as an efficient and recyclable reservoir for loading and release of plant-based mosquito repellents: a new aqueous mosquito repellent formulation

RSC Advances ◽  
2016 ◽  
Vol 6 (33) ◽  
pp. 27301-27312 ◽  
Author(s):  
Wang Delong ◽  
Ma Weibin ◽  
Jia Mingchen ◽  
Yang Zhonglin ◽  
Feng Juntao ◽  
...  
Keyword(s):  
Hydroxyethyl Methacrylate ◽  
Mosquito Repellent ◽  
Mosquito Repellents

Poly(2-hydroxyethyl methacrylate) hydrogels with pendant β-cyclodextrins as an efficient and recyclable reservoir for loading and release of plant-based mosquito repellents.

scholarly journals Pelatihan Pemamfaatan Pestisida alami Berbahan lokal untuk Pencegahan Vektor Demam Berdarah Dengue (DBD) di Kelurahan Kelapa Lima Kota Kupang

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Annytha - Detha
Keyword(s):  
Community Service ◽  
Dengue Hemorrhagic Fever ◽  
Preventive Measures ◽  
Hemorrhagic Fever ◽  
Public Understanding ◽  
Mosquito Repellent ◽  
Counseling Training ◽  
The Public ◽  
Service Activity ◽  
Mosquito Repellents

Community Service Activities have been carried out in Kelapa Lima Village. This activity aims to provide information and knowledge to the public about the dangers of dengue hemorrhagic fever and its preventive measures through the use of potential mosquito repellent plants. Mosquito repellent plants can be found in the yard of the house so that the community can provide land in the yard of their house to plant these plants that have the potential to act as mosquito repellent. The method used in this service activity is in the form of counseling, training, and cultivating plants as an anti-mosquito agent that causes dengue hemorrhagic fever. The conclusion obtained is an increase in the knowledge of the public's understanding of Dengue Hemorrhagic Fever, an increase in public understanding of the bio-ecology of the vector that causes dengue hemorrhagic fever, utilizing plants that have the potential to act as mosquito repellents.

scholarly journals Severe dyspnea and uncontrolled seizures following meperfluthrin poisoning: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shengkun Zheng ◽  
Shengxin Zhang ◽  
Shaoxian Hong ◽  
Qing Lou
Keyword(s):  
Supportive Therapy ◽  
Severe Pneumonia ◽  
Good Health ◽  
Mosquito Repellent ◽  
Case Presentation ◽  
Neurotoxic Effects ◽  
History Of ◽  
Mosquito Repellents ◽  
Short Time

Abstract Background Meperfluthrin is a novel sanitary cyhalothrin insecticide invented in China and has increasingly been used to produce liquid mosquito repellents. Oral meperfluthrin poisoning in human has rarely been reported. Here, we reported a case of meperfluthrin poisoning by ingestion of a meperfluthrin-based liquid mosquito repellent in a 16-month-old infant. Case presentation A 16-month-old boy with a history of accident ingestion of meperfluthrin was admitted to our hospital’s emergency department. He exhibited severe dyspnea, and lung radiograph showed multiple patchy and cord-like high-density shadows bilaterally in a short time. He also suffered 35 min of seizures which were finally controlled by the intravenous infusion of propofol. He was diagnosed with meperfluthrin poisoning, status epilepticus and severe pneumonia. After treated with methylprednisolone, aerosolized beclomethasone dipropionate, anti-infection, and some critical supportive therapy, the patient was in good health and showed no symptoms during 12 months of follow-up. Conclusions Meperfluthrin poisoning is rare. Oral meperfluthrin poisoning shows neurotoxic effects and pulmonary toxicity. Controlling seizures rapidly and ensuring an adequate oxygen supply are critical to the successful treatment.

scholarly journals In Silico Molecular Modeling & Docking of Phytochemical Compounds with Odorant Binding Proteins (OBP1) of Culex Quinquefasciatus.

2019 ◽  
Vol 9 (2) ◽  
pp. 2847-2851
Keyword(s):  
Culex Quinquefasciatus ◽  
Binding Proteins ◽  
Binding Energies ◽  
Human Beings ◽  
Mosquito Repellent ◽  
Odorant Binding Proteins ◽  
Insect Repellents ◽  
Phytochemical Compounds ◽  
Mosquito Repellents ◽  
Odorant Binding

Malaria, Dengue Fever, West Nile Encephalities, Sleeping Sickness, Leishmaniasis, Japanese encephalitis (JE) are the widest large range of diseases causing highest mortality to human beings at Global level and they belong to the group Vector borne diseases (VBD). It is estimated that more than one million deaths were happening every year mostly in tropical regions of South America, Africa & Asia due to these vectors i.e., mosquitoes and mites, which are main disease transporting vectors from one host to another. A remarkable effort has been made to develop various types of insecticides and insect repellents. To control VBD, a bio-defense strategy methods have been employed which were found to be more costly and labour intensive, recurring and time consuming. A new class of repellents were made based on structure based rational approaches of ligand molecules based binding efficiencies with Odorant binding proteins (OBPs) or other olfaction inhibitory compounds with attractive characteristics. But, with very limited knowledge available to screen photo-chemical compounds to design novel mosquito repellents employing a very high-throughput Insilco computational biology methods. Therefore, in this context, we attempted to screen out 3 phytochemicals from different plants exhibiting mosquito repellent activities reported from published literature and various public domains & molecular docking studies, aiming at the Odorant Binding Proteins of Culex quinquefasciatus. The N, N-Diethyl-m-toluamide (DEET) was widely used mosquito repellent chemical chosen as standard reference to validate the binding affinities and specificities of selected compounds aligned with Odoront Binding Proteins. A total of such 50 compounds including DEET were docked against the active site of OBT models or Crystal Structures using AutoDock. Among 5 phytochemical compounds, sum of 3 compounds have resulted in high affinity binding energies & high no of hydrogen-bonds as compared to standard reference of DEET. Among the selected Citronellol, Saponin, and Azadirachtin, are showing the highest docking scores which secure to develop more effective and safer mosquito repellents in future prospect.

scholarly journals KUALITAS SPERMATOZOA TIKUS WISTAR (Rattus norvegicus) SETELAH PEMAPARAN OBAT NYAMUK ELEKTRIK BERBAHAN AKTIF TRANSFLUTRIN

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Elia . ◽  
Lusiana Satiawati ◽  
Janette M. Rumbajan
Keyword(s):  
Rattus Norvegicus ◽  
Seminiferous Tubules ◽  
Control Group ◽  
Mosquito Repellent ◽  
Active Ingredients ◽  
Pyrethroid Insecticides ◽  
Randomized Design ◽  
Testicular Weight ◽  
Male Wistar Rats ◽  
Mosquito Repellents

Abstract: Transflutrin (C15H12CL2F4O2) is an active substance, a derivative of pyrethroid compounds found in electric mosquito repellent. Previous studies showed that group of pyrethroid insecticides can play a role in causing histological changes in testes, decreased testicular weight and reducing diameter of seminiferous tubules. The purpose of this study was to determine the quality of wistar male sperm that are exposed to electric mosquito repellent with transflutrin as active ingredients. This study is experimental with completely randomized design, conducted for 52 days by using eight wistar which consists of two wistar as controls P0, 3 wistar with exposure to electric insect repellent for 8 hours/day (P1), and 3 other wistar for 12 hours/day (P2). The results of this study, the concentration of spermatozoa in the treatment group P1 and P2 respectively at 54.17 x 106 spermatozoa/ml and 45.5 x 106 spermatozoa / ml, in the control group P0 of 59.25 x 106 spermatozoa/ml. Abnormal sperm motility in P1 and P2 is 40% and 35%, at P0 is 45%. Morphologically normal spermatozoa in P1 and P2 is 49% and 78%. It can be concluded that exposure to electric mosquito repellent with transflutrin as active ingredients causes a decrease in sperm quality.Keywords: electronic mosquito repellents, pyrethroid, transflutrin, male wistar rats, sperm qualityAbstrak: Transflutrin (C15H12CL2F4O2) adalah zat aktif yang merupakan senyawa turunan dari pyrethroid dalam obat nyamuk elektrik. Hasil penelitian sebelumnya menunjukkan bahwa insektisida golongan pyrethroid dapat menyebabkan perubahan histologis testis, menurunnya berat testis dan berkurangnya diameter tubulus seminiferus. Tujuan dari penelitian ini adalah untuk mengetahui kualitas spermatozoa wistar jantan (Rattus norvegicus) yang dipapari obat nyamuk elektrik berbahan aktif transflutrin. Penelitian ini bersifat eksperimental dengan rancangan acak lengkap yang dilakukan selama 52 hari dengan menggunakan sampel sebanyak 8 wistar yang terdiri atas 2 wistar sebagai kontrol (P0), 3 wistar dengan pemaparan obat nyamuk selama 8 jam/hari (P1), dan 3 wistar lainnya selama 12 jam/hari (P2). Hasil dari penelitian ini didapatkan konsentrasi spermatozoa pada kelompok perlakuan P1 dan P2 secara berurutan sebesar 54,17 x 106 spermatozoa/ml dan 45,5 x 106 spermatozoa/ml, pada kelompok kontrol P0 sebesar 59,25 x 106 spermatozoa/ml. Motilitas spermatozoa normal pada P1 dan P2 adalah 40% dan 35%, pada P0 adalah 45%. Morfologi abnormal spermatozoa pada P1 dan P2 adalah 49% dan 78%. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa pemaparan obat nyamuk elektrik berbahan aktif transflutrin menyebabkan penurunan kualitas spermatozoa.Kata kunci: obat nyamuk elektrik, pyrethroid, transflutrin, tikus wistar jantan, kualitas spermatozoa

scholarly journals Faktor Risiko yang Mempengaruhi Kejadian Malaria Di Indonesia : Review Literatur 2016-2020

2021 ◽  
Vol 11 (1) ◽  
pp. 16-28
Author(s):  
Maurend Yayank Lewinsca ◽  
Mursid Raharjo ◽  
Nurjazuli Nurjazuli
Keyword(s):  
World Health ◽  
Subtropical Climate ◽  
Mosquito Repellent ◽  
Exclusion Criteria ◽  
Outdoor Activities ◽  
Mosquito Nets ◽  
Study Selection ◽  
Developing Region ◽  
Mosquito Repellents ◽  
Endemic Areas

Malaria is a disease that is still a world health problem, in 2019 the number of malaria cases reached 229 million people. Indonesia is a developing region with a tropical and subtropical climate that is favored by Anopheles sp. Mosquitoes as their habitat. Malaria cases in Indonesia have increased based on the indicator of Annual Parasite Incidence (API) malaria and outbreaks (KLB) in several endemic areas. The purpose of this study was to determine the factors that influence the incidence of malaria in Indonesia by using literature studies in the last 5 years (2016-2020). The method used was a literature review with a literature search component, inclusion exclusion criteria, and study selection and quality assessment. The number of samples of this study were 22 samples of research articles. The results showed that there are several factors that most dominate the incidence of malaria in Indonesia, namely the use of mosquito nets (11 articles), the presence of breeding places (9 articles), the habit of going out at night (9 articles), and the use of mosquito repellents (5 articles). It is hoped that people in malaria endemic areas can use mosquito nets at night, always clean standing water around the house, avoid outdoor activities at night if not needed, and can avoid mosquito bites by using mosquito repellent.

scholarly journals Development of mosquito repellant gel formulations from various natural volatile oils: comparative study with the marketed formulation odomos®

2018 ◽  
Vol 8 (6) ◽  
pp. 106-110 ◽  
Author(s):  
Ruchi S. Shivhare ◽  
Manish A. Kamble ◽  
Debarshi Kar Mahapatra ◽  
Ashwini R. Ingole ◽  
Jagdish R. Baheti
Keyword(s):  
Positive Control ◽  
Mosquito Repellent ◽  
Mosquito Net ◽  
The People ◽  
Tridax Procumbens ◽  
Carbopol 940 ◽  
Mosquito Repellents ◽  
Accelerated Studies ◽  
Cycle Disorders ◽  
Gel Formulations

DEET based mosquito repellents were found to be comparatively harmful to the person suffering from urea cycle disorders such as ornithine transcarbamylase (OTD) deficiency and, are therefore, contraindicated in individuals. These situations lead to the budding necessity of natural mosquito repellents which will have inexpensive, effectual, non-toxic, environment-friendly, and biodegradable attributes. Inspired from the upcoming global need, a carbopol 940 based mosquito repellant gel formulation was prepared from the essential oils of Cymbopogon nardus, Murraya Koenigii, Cymbopogon citratus, Tridax procumbens, Eucalyptus globules, and Azadirachta indica, and further evaluating them for their appearance, pH, viscosity, spreadability, extrudability, swelling index, and accelerated studies. The mosquito repellent potential was evaluated and simultaneously compared with the positive control (Odomos®). In several developing nations, where the majority of the people do not have access to mosquito net, high-cost mosquito repellant creams, and miscellaneous physical methods, this gel formulation may be an effective, inexpensive, and easily accessible way to prevent mosquito-borne diseases, like malaria, dengue, etc. in the lower sections of the society. Keywords: Mosquito, Repellent, Malaria, Gel, Formulation, DEET.

Far Infrared Spectra of Mosquito Repellents

1966 ◽  
Vol 98 (1) ◽  
pp. 76-80 ◽  
Author(s):  
H. B. Rayner ◽  
R. H. Wright
Keyword(s):  
Molecular Weight ◽  
Infrared Spectra ◽  
Infrared Radiation ◽  
Far Infrared ◽  
Mosquito Repellent ◽  
Screening Technique ◽  
Primary Screening ◽  
Mosquito Repellents ◽  
Far Infrared Spectra ◽  
Far Infrared Radiation

AbstractMosquito-repellent chemicals tend to absorb far infrared radiation (below 600 cm.−1) more strongly than do non-repellents of comparable molecular weight. The correlation is probably less direct than was previously supposed, and is hardly strong enough to be used as a primary screening technique.

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