131 article(s) in Science Review

ОСНОВНІ ХАРАКТЕРИСТИКИ СИСТЕМИ ВЗАЄМОДІЇ МЕДИЧНИХ ЗАКЛАДІВ В МЕЖАХ ОДНОГО ГОСПІТАЛЬНОГО ОКРУГУ

the article examines the concept of "hospital district". broad participation of hospital districts requires the implementation of effective forms of partnership in planning and taking strategic decisions on their development. the hospital districts are created to organize a network of health care institutions in the region, in a way that will provide systematic interaction between members of the hospital district, as well as with providers of other types of care (primary, tertiary (highly specialized) medical care, palliative care and rehabilitation), pharmaceutical services. boundaries and composition of each district are formed on the basis of criteria of the district, they are established by the procedure for the creation of hospital districts. the hospital districts are created as "a functional association of hospitals located in a particular area". health establishments, which belong to the hospital district, remain in the ownership and subordination of local authorities who are members of the hospital district. to improve secondary healthcare, hospital council are created with the aim of coordinating actions, devising ideas the on organization and operation of medical care within a separate hospital district, preparation and confirmation of the prospective development plans of hospital districts for 5 years (taking into account the needs of modernization and resources). Show More ... ... Show Less

  • Hospital District
  • Medical Care
  • Health Care
  • Palliative Care
  • Area Health
MORPHING OF MASS CONSCIOUSNESS AND REMYTHOLOGIZATION IN SITUATION OF GLOBALIZATION

the article is devoted to the changes in society and public consciousness in the conditions of globalization. phenomenon of mass consciousness and its differences of public consciousness are analyzed in the article. an important point to disclose a new rationality is an understanding of the connection that can give unity to the consciousness of an individual person and to a certain social group is a myth. mythology in conditions of globalization processes can be defined as remythologization. myth as a part of mass consciousness becomes an attractive element for the manipulation of mass consciousness, as an instrument to solve political ambitions, to manage groups of people. it can be observed in the process of myth-creation, in the formation of “pictures of the world” and ideologies, in the development of informational and psychological wars, in the formation of public opinion. Show More ... ... Show Less

  • Mass Consciousness
  • Public Consciousness
  • Public Opinion
  • Social Group
  • The World
МІКРОСКОПІЧНА БУДОВА ОРГАНІВ КУРЧАТ- БРОЙЛЕРІВ ЗА ЗБАГАЧЕННЯ РАЦІОНУ КОМПЛЕКСОМ НАНОМІКРОЕЛЕМЕНТІВ (Zn, Cu, Ag, Co, He, Mg

the work is devoted to the study of the microscopic structure of broiler chickens organs for the enrichment of the diet with a complex of nano trace elements which include the citrates of nano zn, cu, ag, co, he, mg. it was found that the use of a complex of nano-micronutrients, at a dose of 1 cm3/dm3 of drinking water in the drinking mode for five days in a row after five days, did not cause pathomorphological changes in the internal organs and skeletal muscles of slaughtered broiler chickens.the use in the diet of the experimental bird complex of nano trace elements at a dose of 10 and 20 cm3/dm3 drinking water can lead to structural disorders in the liver, kidneys and spleen in the form of local circulatory disorders, necrosis of cells of the parenchyma of organs. extracapillary glomerulonephritis and necrotic- dystrophic changes in the epithelium of the tubules are recorded in the kidneys (proteinaceous nephrosis by type of granular dystrophy, in some cases necrotic nephrosis); in internal organs there are local circulatory disorders (congestive hyperemia, stasis, etc.). in cells of parenchyma of organs destruction of organelles, cell membranes is registered, that causes at first development of dystrophic processes on decompositive type, and subsequently - death of cells. Show More ... ... Show Less

  • Trace Elements
  • Drinking Water
  • Internal Organs
  • Circulatory Disorders
  • Experimental Bird
MAIN FEATURES OF CHINA-KAZAKHSTAN ECONOMIC INTEGRATION

kazakhstan is the largest and most developed state among central asian countries, with rich base of natural resources. in its foreign policy, kazakhstan places the development of good-neighborly relations with china on the first place. in turn, for the people’s republic of china, kazakhstan is the second largest trading partner after russia and the biggest hub for further transportation of goods, which has big positive effect on economic relations between these two countries. the chinese factor is constantly operating for the foreign policy of the republic of kazakhstan. this paper studies economic integration and main features of trade and economic cooperation in china- kazakhstan relations. Show More ... ... Show Less

  • Foreign Policy
  • Economic Integration
  • The People's Republic Of China
  • Central Asian Countries
  • Positive Effect
CHINA − KAZAKHSTAN ECONOMIC COOPERATION AND ONE BELT ONE ROAD CONSTRUCTION

china and kazakhstan are long-term partners, which economic relations have reached a new level of the strategic partnership. the “one belt, one road” initiative brings new opportunities and challenges for the development of bilateral economic interactions and for the entire central asia region. the author made an original analysis of the main components of economic cooperation between the two countries, including energy cooperation, current trade infrastructure and identifying the prospects for implementation of the “one belt, one road” initiative. based on the long-term relationship, strategic partnership and trade cooperation between china and kazakhstan, construction and combining of the chinese “one belt one road” initiative and kazakhstan “bright road plan” is the new era for china-kazakhstan economic development. according to the current research, the construction of this infrastructure will have a direct impact on flows of foreign investments, production development and transport infrastructure. in addition, the construction of the “one belt, one road” plan has a great importance for promoting the development of chinese-kazakh economic relations and solving difficulties in economic exchanges Show More ... ... Show Less

  • One Belt One Road
  • The One
  • Long Term
  • Economic Cooperation
  • Strategic Partnership
ПАТОМОРФОЛОГІЧНІ ЗМІНИ СТРУКТУР ПІДНИЖНЬОЩЕЛЕПНОЇ СЛИННОЇ ЗАЛОЗИ НАПРИКІНЦІ 6-Го ТИЖНЯ ЕКСПЕРИМЕТАЛЬНОГО ОПІОЇДНОГО ВПЛИВУ

the significant using of drugs and the prevalence of drug addiction in the last decades necessitates the study of the effects of opioids on the structural organization of organs and systems. the people with drug addiction syndrome have functional disorders of the salivary glands earlier than morphological changes in the mucous membrane of oral cavity.reducing the amount of saliva and changing its composition lead to negative changes in the oral barrier function, salivary ph which is the main natural regulator of oral cavity homeostasis. this publication demonstrates the morphological changes of the submandibular salivary gland under the opioid effect at the 6th week of the experimental research. Show More ... ... Show Less

  • Drug Addiction
  • Morphological Changes
  • Oral Cavity
  • Salivary Glands
ФАКТОРИ РИЗИКУ ГІПОКСИЧНО-ІШЕМІЧНОЇ ЕНЦЕФАЛОПАТІЇ НЕДОНОШЕНИХ НОВОНАРОДЖЕНИХ

the article presents the results of an assessment of risk factors for the development of hypoxic-ischemic encephalopathy in premature newborns. perinatal risk factors for hypoxic-ischemic encephalopathy in premature newborns were the factories that lead to the development of placental dysfunction, fetal growth retardation, antenatal fetal distress and premature birth. the most important factor in the development of gie is gestation (up to 32 weeks gestation), placenta previa with bleeding and premature placental abruption in the given time. Show More ... ... Show Less

  • Risk Factors
  • Hypoxic Ischemic Encephalopathy
  • Premature Newborns
  • Growth Retardation
ІМІДЖ ЯК ІНСТРУМЕНТ ФОРМУВАННЯ КОНКУРЕНТНОЇ СТРАТЕГІЇ ТУРИСТИЧНОГО ПІДПРИЄМСТВА

the article deals with the specifics of forming and diagnosing the image of a tourist enterprise. considers the image as a strategic management tool aimed at ensuring a high level of competitiveness of an enterprise. in the context of competitive advantages, the goals, characteristics and principles of creating and correcting the image of a tourism enterprise are considered. the article substantiates the methodology of complex image evaluation, which reflects the attitude of different contact groups to the tourist enterprise, reveals the motives for their interaction. the methodology involves the scoring of the image by certain parameters and the calculation of the integral index, which comprehensively allows characterizing the image strategy of a company and comparing it with others in the chosen field of activity. Show More ... ... Show Less

  • Strategic Management
  • Management Tool
  • Image Evaluation
  • Integral Index
  • Complex Image
A SIMULATION MODEL FOR MANAGING PARAMETERS OF INTELLIGENT SECURITY SYSTEM

security systems are the guarantee of stable functioning of the organization, company, office, industry, housing and other types of buildings. for entire security, complex control devices are set on the building which has to be protected, like fire and burglar alarms, video-audio controls and access systems. intelligent security management system is built on atmel’s microcontrollers. this allows the system to be flexible and to modify it easily if needed. the reliability of the security system depends on its uniqueness. this given security system is easily modified and hence its reliability is high. the system can be easily integrated into a variety of external modules, which can further increase the factor of reliability. it’s also easy to adopt it to various security management systems. many of the security and video surveillance systems allow to control the situation of the object from a large distance. from any point of the planet, we can track and manage the security system modes and make easy changes in them, which enable adequate reaction.digital complexes of video surveillance are one of the variants of defense organization. the main areas of their use are the most important objects and large areas where buildings are located far from each other. Show More ... ... Show Less

  • Security System
  • Video Surveillance
  • Security Management
  • Intelligent Security
  • Control Devices
МЕТОДИКА ВИЗНАЧЕННЯ НОМІНАЛУ НАВІСНИХ ЕЛЕМЕНТІВ ШЛЕЙФІВ НЕАДРЕСНОЇ ПОЖЕЖНОЇ СИГНАЛІЗАЦІЇ

the fire alarm system shall detect the initial signs of fire at an early stage of its occurrence and shall not give false positives. it also depends on balancing the fire alarm loop with the fire receiving control device. the use of devices from different manufacturers in the construction of a fire alarm may result in the malfunctioning of such a system and giving false signals.the article presents the results of the analysis of the state of non-address fire control receivers of different manufacturers, depending on the mode of the fire alarm loop, in which he may be. the received generalized nomogram of states of non-address control devices depending on the resistance of the fire plume is presented. a method for determining the resistance of loop elements against different fire detectors is proposed and an appropriate algorithm is developed. Show More ... ... Show Less

  • Fire Alarm
  • Alarm System
  • Fire Plume
  • Fire Control
  • Control Devices
SUBSTANTIATION OF THE METHODOLOGICAL EXPEDIENCY TO USE THE METHOD OF WRITING ESSAYS ON SOCIAL AND PEDAGOGICAL TOPICS

the article presents an attempt to provide a comprehensive substantiation of the feasibility of using the method of writing an essay on social and pedagogical topics during the teacher training process. based on the interpretation of the method essence, its functional purpose in philosophical and linguistic literature as well as works on literary studies, they determine the adaptation foundations regarding the specific features of the effective use of the essay method in the educational process, pedagogy as an academic discipline. specific examples are used to demonstrate the priorities of the essay method when developing social competence in particular and the social reflection of the future teacher in general. they mention the strengthening of the roles of the student’s activities related to self-education and self-assessment, development of their creative reflective thinking, and the strengthened ability to make effective decisions regarding a burning problem of both professional and social significance. Show More ... ... Show Less

  • Teacher Training
  • Social Competence
  • Social Significance
  • The Future
  • Functional Purpose
ТЕРМІНИ-ПАРОНІМИ ТА ПИТАННЯ КУЛЬТУРИ НАУКОВОГО МОВЛЕННЯ

the article deals with the issue of the culture of the ukrainian scientific text, in particular, the difficulty in ensuring accuracy as a communicative feature of speech due to paronyms in terminology of various sciences; it also outlines the views of modern linguists on this lexical and semantic phenomenon, presents the definitions available in the scientific literature, analyzes semantic and structural features of these units, the ways of creating them and distinguishing between them, and illustrates the classification characteristics of full and partial paronyms by the example of linguistic terminology. Show More ... ... Show Less

  • Scientific Literature
  • Structural Features
  • Scientific Text
ДИДАКТИЧНІ ПРИНЦИПИ ФОРМУВАННЯ ЦИФРОВОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ ФАХІВЦІВ-ЕКОНОМІСТІВ

in the article the author defines didactic principles as a system of basic requirements, which should be guided in determining the content, forms of organization and teaching methods, which will most contribute to the formation of digital competence of future specialists of economic profile in accordance with the purpose of the chosen educational program (economics; information systems in economics and business analytics; business economics; enterprise economics; economic cybernetics; international economics; personnel management and labor economics, etc.), common with task of training and education, patterns of learning.the following didactic principles are characterized: scientific, systematic and consistent, accessibility, consciousness and activity of learning, clarity, strength of knowledge, communication of theory and practice, emotionality, control and correction of knowledge, optimization of learning. the mechanisms of implementation of these principles are disclosed. Show More ... ... Show Less

  • Information Systems
  • Personnel Management
  • Educational Program
  • Economic Profile
  • Knowledge Communication
ПОСТАТЬ МИРОНА ФЕДОРІВА В ОЦІНЦІ ПЕРІОДИКИ УКРАЇНСЬКОЇ ДІАСПОРИ (НА ПРИКЛАДІ ГАЗЕТИ «СВОБОДА

on the basis of materials of ukrainian-language periodicals are described the main artistic achievements of the ukrainian composer, conductor, public figure and musicologist myron fedoriv’s (1907-1996). reflected a wide range of bibliographic and factual information of the artist’s life, which made it possible to clarify the historical, cultural and artistic conditions for the formation of the creative personality of a professional musician; specificity and leading directions of his versatile musical and educative activities. special attention is paid to the issue of actualization of the composer's artistic and creative heritage in the context of popularization of the national song tradition in the cultural and artistic environment of the ukrainian western diaspora. the article deliver the evaluative judgments of modern scholars and individual publication authors, which characterizes the importance of personal contribution to the preservation of ukrainian spiritual and musical culture abroad. Show More ... ... Show Less

  • Factual Information
  • Public Figure
  • Professional Musician
  • Creative Personality
  • Wide Range
ВИВЧЕННЯ ВПЛИВУ БІОПРЕПАРАТІВ ЗА РІЗНИХ НОРМ ВНЕСЕННЯ НА ПРОДУКТИВНІСТЬ ПШЕНИЦІ ОЗИМОЇ В УМОВАХ ПІВНІЧНОГО СТЕПУ УКРАЇНИ

the article investigated the effect of biological products for different application rates on the productivity of winter wheat in the northern steppes of ukraine. the technology of growing winter wheat has been determined, which is based on optimizing a huge number of different conditions that affect the formation of high grain productivity of the required quality. growing technologies pay great attention to sowing dates, which directly affect not only the quantity and quality of the crop, but also the formation of plant resistance to many adverse factors. the weather conditions on which the studies were conducted are analyzed. the biometric indicators of winter wheat plants were revealed, namely: tillering coefficient, coefficient of secondary roots, number of grains in an ear, weight of a thousand seeds. the yield of winter wheat was determined depending on the proposed experimental design. Show More ... ... Show Less

  • Winter Wheat
  • Experimental Design
  • Plant Resistance
  • Required Quality
  • Secondary Roots
RECENT CHANGES AND CURRENT GAPS IN UKRAINIAN COMPETITION LAW

competition law plays an enormous role for development of the economy of ukraine. association agreement signed with the european union pushed ukrainian competition authority to move forward and fight against anticompetitive agreements. anti-monopoly committee of ukraine has quite sufficient experience in investigation and fighting against cartel agreements. despite the fact that ukrainian government gives all efforts for creating free and undistorted competition on the market and tries to maintain market without any restrictive agreements, there are many challenges and gaps to be improved. this paper points out authority and competence of amcu, recent changes and current gaps in ukrainian competition law. Show More ... ... Show Less

  • Competition Law
  • Competition Authority
  • The European Union
  • Association Agreement
ARRANGEMENT AND MODULATION OF ETL PROCESS IN THE STORAGE

data warehouse (dw) is the basis of systems for operational data analysis (olap-online analytical processing). data extracted from different sources transforms and load in dw. proper organization of this process, which is called etl (extract, transform, load) has important significance in creation of dw and analytical data processing. forms of organization, methods of realization and modeling of etl processes are considered in this paper. Show More ... ... Show Less

  • Data Analysis
  • Analytical Processing
  • Operational Data
  • Important Significance
  • Different Sources
ABOUT POSSIBILITY TO CLASSIFY COAL LAYERS HAZARDOUS CHARACTERISTICS BY GENETIC AND PROCESS PARAMETERS OF COALS

the analysis of ukrainian legal environment has been performed for solid fossil fuels production, which has shown existing of contradictories between parameters describing the accuracy of forecast to manifest the coal layers hazardous characteristics during independent of mining and does not exclude any possibility for emergency situation to occur, independent of the preventive measures full implementation. the base to determine the coal layers hazardous characteristics are: average reflectance of vitrinite, presence of some components in organic matter (с0, о0, н0, n0), alteration of moisture and mineral impurities content. for these classificatory parameters, their quantitative assessment is available in the whole multiplicity of coals metamorphic transformation. the specific electrical resistivity logarithm and other proxy parameters may serve as additional classificatory parameters to reveal any hazardous characteristics of anthracites after grounding their using in some ranges of metamorphism series. it has been established that the existing wide range of vitrinite reflectance alteration for anthracites specifies significant alterations in the fossil fuel structure and properties. in their process of metamorphism, these peculiarities of anthracite alterations have almost not been classificatory established by their genetic and process parameters. Show More ... ... Show Less

  • Process Parameters
  • Electrical Resistivity
  • Organic Matter
  • Quantitative Assessment
  • Wide Range
THE STUDY OF CELLULAR FACTORS OF IMMUNITY IN PATIENTS WITH NON-HODGKIN's LYMPHOMAS

the purpose of this study was to study the basic cellular indicators of immunity in patients with non-hodgkin's lymphomas to substantiate the immunopathogenetic features of the course of the disease. it turned out to be important that patients were divided into 2 groups with virus carrier and without virus carrier.an analysis of the results allowed us to identify pronounced changes in the cellular immunity that manifested themselves by suppressing the expression of cd3 +, cd3 + cd4 +, iri, against this background, an increase in the expression of cd3 + cd8 +, cd16 + and cd20 + b cells, as well as increased expression of activation molecular markers of cd38 + lymphocytes, cd95 +. deep t-cell immunodeficiency was detected against the background of pathological activation of lymphocytes, which is clinically often reflected by frequent relapses, an unfavorable course of the disease, and treatment results Show More ... ... Show Less

  • Hodgkin's Lymphomas
  • Molecular Markers
  • Frequent Relapses
  • T Cell Immunodeficiency
  • Virus Carrier
PARALLEL STUDY OF HEMORHEOLOGICAL, INFLAMMATION AND ANEMIA PARAMETERS BEFORE, DURING AND AFTER SURGERY IN PATIENTS WITH STOMACH CANCER

the aim of our work was to study the biomechanical markers of blood flow in patients with stomach cancer. therefore, we paid attention to the parameters of hemorheology, rheology, inflammation and anemia in the group of patients with stomach cancer and in the control group; with the help of a new surgical technique, we simultaneously examined the flow parameters in the central blood and locally at the site of tumor growth during the operation. as a result of the matrix analysis and statistical data processing, it turned out that in the group of patients the average values of hemorheological parameters went beyond the limits of the clinical norm and significantly differed from the parameters in the control group. moreover, the parameters of inflammation and anemia also differed in the group of patients from the values of the control group, but with a little difference. consequently, the parameters of hemorheology, inflammation, and the parameters that determine the presence of anemia are variable in the local circulation as compared to the central one, mainly due to the hemorheological component Show More ... ... Show Less

  • Stomach Cancer
  • Control Group
  • Blood Flow
  • New Surgical Technique
STRATEGIC DIRECTIONS FOR DEVELOPMENT OF WATER SUPPLY AND WASTEWATER SPHERE OF UKRAINE

the article considers the need for the development of a strategy for the development of the water supply and wastewater sector in ukraine. the author of the article argues that without a strategy, the effective functioning and development of the water supply and wastewater system is impossible. strategic planning in the field of water supply and wastewater of ukraine is the development of a vision of a key element of modern management, which the state considers as the development of the water supply and wastewater sector in the future. the concept and essence of strategy in general are analyzed, the vision and mission of the sphere of water supply and wastewater of ukraine are determined. the strategy of development of the sphere of ukraine till 2020, external and internal institutions that influence the vectors of development of the water supply and wastewater sector are considered. the author presents the priority goals of the development of the water sector, identified by international organizations over the past five years. the author proposes strategic directions for the development of the water supply and wastewater system with the justification of their implementation Show More ... ... Show Less

  • Water Supply
  • Strategic Planning
  • International Organizations
  • Water Sector
  • The Future
РАСПРОСТРАНЕННОСТЬ КИШЕЧНЫХ ПАРАЗИТОЗОВ У ВИЧ-ПОЗИТИВНЫХ ПАЦИЕНТОВ

a cross-sectional study among people living with hiv (plhiv), who are naive and who are on antiretroviral treatment (art) was conducted in kyiv, ukraine from january 2017 to june 2019. in 200 samples of feces from plhiv were detection intestinal parasites and helminthes. also in all patients was measure of cd4 t cells by flow cytometry technique and the viral load of hiv (hiv vl) by reverse transcription and polymerase chain reaction, sensitivity of test – 40 copies hiv rna / ml. the study shows high prevalence of intestinal parasitic in population of plhiv – 30,0%. the most prevalent parasites were cryptosporidium (10,5%), ascaris lumbricoides (1,5%), g. lamblia (0,5%). opportunistic protozoans (b. hominis) were found in 15.5% of plhiv. among plhiv with intestinal parasites severe immunosuppression (< 200 cd4 cells/ml) were more common (66.7%) than among plhiv without intestinal parasites (45.7%); patients with undetectable hiv vl (35.0%), patients receiving art for more than 6 months (28.3%) were less common (55.7% and 54.3% respectively). in all cases p value was less than 0.05. our data show that detection even opportunistic intestinal protozoans in plhiv can be used as a marker of immune suppression and hiv replication activity, and confirms the importance of parasitological surveillance in this group of patients Show More ... ... Show Less

  • Intestinal Parasites
  • Flow Cytometry
  • Polymerase Chain Reaction
  • Replication Activity
ERICH FROMM’S "HUMANISTIC RADICALISM". HISTORICAL OCCURRENCE AND POLITICAL ACTIVITY

the purpose of this article was to study the creative heritage of erich fromm and the formation of «humanistic radicalism». the study was aimed at defining the historical context for the theoretical formation of «humanistic radicalism» within the framework of fromm's «social psychoanalysis» and the practical implementation of this concept in the political activities of this personality. four periods of the introduction of the ideas of «humanistic radicalism» by e. fromm through his political activities were identified. it was found out that the humanistic orientation requires the continuation both in research activities of a person and in everyday socio-cultural life in general, while maintaining dialogical relations with the world Show More ... ... Show Less

  • Political Activities
  • Practical Implementation
  • Cultural Life
  • Research Activities
  • The World
КУЛЬТУРНОСЕМІОТИЧНИЙ, МЕДІАТЕХНОЛОГІЧНИЙ, КОМУНІКАТИВНИЙ ПІДХОДИ У ДОСЛІДЖЕННІ ПОНЯТТЯ «ІНТЕРМЕДІАЛЬНІСТЬ

intermediality has been described as phenomenon of interartistic interaction and actual scientific approach of interdisciplinary studies. different approaches of ukrainian and foreign researchers for defining this concept have been analyzed. it has been generalized that intermediality is interpreted as interaction of semiotic codes of different arts in the multimedia space of culture. it has been emphasized that the basis of intermediality is inter- semiotic interaction, comparative analysis of texts (digital non-digital), system of communicative competence and personal aesthetic experience. the main approaches to the classification of interartistic relations have been analyzed. taking into account the polysemy of the notion of «media» (as a carrier of information, a sign system, technical means of communication, a way of communication) the idea has been is grounded on the fact that today the concept of «intermediality» should be considered from three sides: cultural-semiotic, media-technological and communicative. in view of this, three approaches to the understanding of intermediality have been outlined: cultural-semiotic, media-technological, communicative Show More ... ... Show Less

  • Comparative Analysis
  • Aesthetic Experience
  • Communicative Competence
  • Interdisciplinary Studies
THE STUDY OF HUMORAL FACTORS OF ADAPTIVE IMMUNITY IN PATIENTS WITH NON-HODGKIN’S LYMPHOMAS

it is known that humoral factors of immunity play an important function of mediators in the cascade development of the immune response and can determine the effectiveness of the final, effector reactions of cellular immunity in the inactivation and elimination of antigens. serum concentrations of major immunoglobulins igg, iga, igm in nhl were analyzed. the highest serum content of igg and iga was revealed in the groups of patients with virus carrier. it has been established that one of the most important humoral markers of immunity is the circulating immune complexes (cic). it has been established that one of the most important biological functions of immunoglobulins is antigen binding and the formation of cic. a high level of cic in nhl may be due not only to the activation of the immune response, but also to the suppression of the mechanisms of their elimination. therefore, based on the results obtained, with nhl there is a pronounced imbalance of humoral immunity. cic of large and small sizes are also increased, however, the highest increase in cic was observed in groups of patients before chemotherapy with virus-bearing. an increase in the main immunoglobulins indicates the presence of humoral imbalance, and an increase in the cic indicates the presence of intoxication of the body either due to the decay of the tumor cells themselves and infected cells, which almost always indicates the progression of the pathological process Show More ... ... Show Less

  • Immune Response
  • Humoral Factors
  • Tumor Cells
  • Cellular Immunity
  • Virus Carrier
Science Review
  • 2019;
  • Science Review
ENVIRONMENTAL POLLUTION WITH HEAVY METALS AND SELECTIVE SENSITIVITY OF SOME SPECIES OF MEDICINAL PLANTS

heavy metals are especially dangerous in the registry of polluting agents of the environment, as the heavy metals are hazardous to human health and it is particularly dangerous because getting the heavy metals into the living organism is a provocative factor of the dangerous disease such as malignant tumors, diseases of cardiovascular system or nervous system.the problem of the environmental pollution with heavy metals is a priority and urgent problem. therefore, we aimed to study the peculiarities of the accumulation and dynamics of heavy metals in the polluted and clean environment in different types of medicinal plants grown in adjara region. the study of annual absorption of heavy metal in the medicinal plants, i think, will have a practical value, because since we often use medicinal plants to help prevent different diseases, it is possible to provoke another disease. through the plants we used to study Show More ... ... Show Less

  • Heavy Metals
  • Medicinal Plants
  • Environmental Pollution
  • A Priority
СЕМЕЙНЫЕ СПОРЫ И МЕДИАЦИЯ

disputes arising from family legal relations can be settled in the republic of armenia also by alternative means of dispute settlement. by means of reconciliation the disputes arising from family legal relations may be settled with participation of a reconciler, licensed under court procedure. Show More ... ... Show Less

  • Dispute Settlement
  • Alternative Means
  • The Republic
FEATURES OF THE COMORBID FLOW OF UNSTABLE STENOCARDIA AND THE ANXIETY-DEPRESSIVE SYNDROME DEPENDING ON THE BLOOD CYTOKINE LEVEL

195 patients (102 men and 93 women) aged from 35 to 75 years (mean age 62.57 ± 0.75 years) suffering from unstable forms of ihd were examined on the basis of the sb rscema in the emergency and cardiac resuscitation departments. all patients were tested using the hospital anxiety and depression scale. based on the psychopathological examination data, all patients were divided into 2 groups. the first group included 109 patients with unstable angina with clinically significant affective disorders, which amounted to 55.89%. the second − the comparison group - 86 (44.1%) patients with unstable angina without affective disorders. studies have shown that when comparing inflammatory markers − cytokines in patients with unstable angina, the pro-inflammatory cytokines il-1 and tnfα are increased in individuals with comorbid pathology, depending on the presence or absence of affective disorders of the anxiety-depressive spectrum Show More ... ... Show Less

  • Unstable Angina
  • Affective Disorders
  • Inflammatory Markers
  • Pro Inflammatory Cytokines
ЛІТЕРАТУРНІ СЮЖЕТИ В ТВОРАХ Е. ДЕЛАКРУА – “ЗАГИБЕЛЬ КОРАБЛЯ ДОН-ЖУАНА” ТА “ПІСЛЯ КОРАБЕЛЬНОЇ АВАРІЇ

in this article, we have studied problems associated with features of the painting development in the romantic era. we have highlighted questions on the interrelationship between literature and painting and considered new trends in the development of the french painting in the first half of the 19th century. artists of this era, in particular e. delacroix, searched for new subjects actively by finding interesting themes in works of the world literature. e. delacroix was inspired by works of dante, l. ariosto, t. tasso, w. shakespeare, j. goethe, g. byron, f. r. de chateaubriand, w. scott etc. among them we should make the english writer g. byron stand out: his character personified the romantic ideal of the whole era and his heroic life became a role model for young generation. in byron’s works eugène delacroix was searching for new themes and his romantic hero and every time finding the relevant ways for his artistic solution system. е. delacroix’s works show us the integrity of romantic ideas clearly and the close mutual influence of the western european literature and french painting allows speaking about the uniqueness of this era Show More ... ... Show Less

  • French Painting
  • 19Th Century
  • Young Generation
  • Solution System
  • The World
ТРЕНІНГ ЯК МЕТОД РОЗВИТКУ ЛІДЕРСЬКИХ ЯКОСТЕЙ ЗДОБУВАЧІВ ОСВІТИ ПРОФЕСІЙНО (ПРОФЕСІЙНО-ТЕХНІЧНИХ) НАВЧАЛЬНИХ ЗАКЛАДІВ

the article reveals the essence of the "training" concept, describes some historical aspects of the training work usage by different researchers, the necessity of the use of training as an important method for the development of leadership qualities in professional (vocational) educational establishments is substantiated. it was described and analyzed functions that it performs, such as: motivational-inductive, educational-pedagogical, developmental, educational, communicative-compensatory and relaxation. the tasks of the training are highlighted, their purpose, content and structure are given. conditions in which the leadership qualities of educators develop are characterized, such as: psychological-pedagogical, psychological- administrative and individual-psychological. in the process of training program elaborating, a selection of forms and methods was developed for the development of motivational, communicative-organizational, emotional- volitional, cognitive and personal components. an orientation towards an integrated approach is taken, which includes: activity, procedural, systemic, existential and subjective-behavioral approaches. the necessity of training implementation in the educational environment for the development of the leadership potential of students of professional (vocational) educational establishments is noted. Show More ... ... Show Less

  • Leadership Qualities
  • Training Program
  • Educational Environment
  • Important Method
АСПЕКТИ ФУНКЦІОНУВАННЯ MICE-ТУРИЗМУ В РАМКАХ РОЗВИТКУ ПОДІЄВОГО ТУРИЗМУ В РЕГІОНІ

the article deals with the general tendency of tourism development in the world. particular attention is paid to the impact of event tourism on the development of territories. it is determined that a significant share of the gdp of the region is the proceeds from the event-tourist activity. the emphasis is on the role of mice − tourism as a significant component of event tourism. it has been found that this type of tourism is effective for developing countries as an opportunity to enter international markets. in the article the becs cube is proposed as a visual model of the interaction of the main spheres of life in society and the structural scheme of the interaction of these spheres with the use complexity of mice-tourism. it is proposed to use a synergistic approach in event tourism as a way to determine the main aspects of the development of this field of activity Show More ... ... Show Less

  • Event Tourism
  • Mice Tourism
  • The World
  • The Impact
SELECTION OF THE OPTIMUM MODEL OF MANAGEMENT IN WATER SUPPLY AND WASTEWATER SPHERE OF UKRAINE

the article is devoted to the analysis of european models of water supply and wastewater management and their implementation in ukraine. the authors review the classical models of eu water supply and water dsposal management: english, french and german, their historical and political roots, the theoretical basis. in parallel, the authors analyze the state policy in the sphere of water supply and wastewater of ukraine, the principles of its formation and features, the current state of the sphere of water supply and wastewater, organizational and legal forms of water supply and wastewater enterprises. the article analyzes the current state of realization of public- private partnership in the field of water supply and wastewater with indication of existing contracts and contracts that have become invalid. it is proved that the difference between the water supply and wastewater companies of different management models in ukraine is not marked, as the general state of the water supply and wastewater sector shows the existence of common problems characteristic of all enterprises. in particular, the ineffectiveness of tariff policies, depreciation of fixed assets, low quality of services, difficult financial condition, inadequate investment, etc. the authors discuss the possibilities of adaptation of classical management models in ukraine and possible consequences. the article defines the institutional problems of the state policy of ukraine in the sphere of water supply and wastewater, which influence the efficiency of the implementation and functioning of any model of management and regulation Show More ... ... Show Less

  • Water Supply
  • State Policy
  • The State
  • Management Models
  • Current State
THE SUBJECT OF THE QUESTION IN MAONIC SCIENCE AND ITS CLASSIFICATION

the topic of the talk and its classification are one of the central issues of syntax. this article compares the classification of the arabic alphabet with the arabic and uzbek linguistic norms. in terms of the stylistics of the uzbek language, it is explained in terms of how the spelling of the arabic word begins, and the classification of the muslim in terms of the context. it is emphasized in maonic science that the most important aspect of non- speaking in other languages, especially in the arabian minority, is the purpose of the speaker and the state of the listener. in maonical science there is information on classification in relation to reality, the goal of the speaker and the status of the listener, and in the so-called interpreter, to be a change in reality, and to choose the types of speech Show More ... ... Show Less

  • The State
  • Arabic Word
  • The Subject
  • The Status
ГУМАНИЗАЦИЯ И УСТОЙЧИВОЕ РАЗВИТИЕ АРХИТЕКТУРНОЙ СРЕДЫ МЕДИЦИНСКИХ КОМПЛЕКСОВ

a study of the main criteria for sustainable development in architecture of large medical complexes and their impact on recovery of patients are pointed out in the article. this study was conducted on the basis of analysis of foreign materials and research work. a new stage in sustainability of medical complexes architecture, as an architecture that brings recovery was revealed. synthesis, analysis and conclusions taken from books, articles and design experience of modern medical complexes are results of this study. the result of this study is that main design directions of modern medical complexes have been formulated. this article has practical significance, so obtained results will interest practicing architects who are faced with the task of creating a comfortable and healthy environment, as well as for those people who are responsible for design and operation of such objects. modern criteria of sustainability in architecture of medical complexes help to create a healthier environment, improve public perception and increase the efficiency of such institutions Show More ... ... Show Less

  • Sustainable Development
  • Public Perception
  • Practical Significance
  • Main Design
  • Design Experience
ГЕОИНФОРМАЦИОННАЯ СИСТЕМА ДЛЯ АНАЛИЗА ДАННЫХ ЭКОЛОГИЧЕСКОГО МОНИТОРИНГА УКРАИНСКОЙ ЧАСТИ ДЕЛЬТЫ ДУНАЯ

for forecasting of the change of water quality in ukrainian part of danube delta the geographic information system (gis) of the ecological monitoring had been designed. to this gis a number of functions had been added including the function of the analysis of the temporary rows of observation results. by means of designed gis the main trends of the change of the water quality for period, since 2004, have been identified. for majority of the water quality parameters the trends to improvement of water quality have been identified. the trend to deterioration of water quality has been identified for manganese concentration only. increasing of manganese concentrations existed already in the inlet checkpoint of ukrainian part of danube delta (above reni Show More ... ... Show Less

  • Water Quality
  • Danube Delta
  • Geographic Information System
  • Observation Results
CLINICAL SIGNS AND DIAGNOSIS OF ADENOVIRUS CONJUNCTIVITIS

the features of the clinic and treatment of patients with adenoviral keratoconjunctivitis were studied on the example of 112 patients aged 19- 57 years Show More ... ... Show Less

  • Clinical Signs
ПРАГМАТИКО-СТИЛІСТИЧНІ ОСОБЛИВОСТІ ПЕРЕКЛАДУ ДРАМАТИЧНОГО ТЕКСТУ (НА МАТЕРІАЛІ ТВОРУ Т. ВІЛЬЯМСА «A STREETCAR NAMED DESIRE» ТА ЙОГО УКРАЇНСЬКОМОВНОГО ТА РОСІЙСЬКОМОВНОГО ВАРІАНТІВ

this study attempts to provide some insight into the relevance of cultural factors in the translation of dramatic texts. the present research aims at determining the ways of adequate reproduction of national and cultural identity of the play of tennessee williams “a streetcar named desire”. the article deals with the most effective ways of translation of phraseological units and proper names in drama. the main problem during the translation of phraseological units and proper names is determined; it lies in the fact that they have a certain stylistic feature, expressiveness that are depended on the context. the combination of several approaches within a single study makes it possible to describe the peculiarities of the individual style of the writer, and this provides a complete understanding of the selection principles of linguistic means by the author Show More ... ... Show Less

  • Proper Names
  • A Streetcar Named Desire
  • Individual Style
  • Insight Into
ДІОКСИД ХЛОРУ В АСПЕКТІ МІКРОБІОЛОГІЧНОЇ БЕЗПЕКИ ВОДОПРОВІДНОЇ ВОДИ

in the article the use of chlorine dioxide for disinfection of water from dnipro river are considered. the results of the industrial testing of disinfection chlorine dioxide technology with using of de nora model t70g4000 chlorine dioxide generator for kyiv water supply system are presented. the model t70g4000 chlorine dioxide generator is a two-chemical system, utilizing commercially available concentrations of hydrochloric acid (32-33%) and sodium chlorite (24-25%) in the production of chlorine dioxide. no chlorine gas is required. use of solutions of chlorine dioxide for treatment of tap water with concentrations 1,5 mg/dм3 at first stage and 0,3 mg/dм3 at second stage were effective. the use of chlorine dioxide for water disinfection increases the microbiological safety of drinking water supply Show More ... ... Show Less

  • Chlorine Dioxide
  • Water Supply
  • Drinking Water
  • Second Stage
  • Chlorine Gas
AGRICULTURAL PRODUCTION COSTS, PRODUCT COST AND WAYS TO REDUCE IT IN UZBEKISTAN

the cost of production is one of the most important indicators of the economic efficiency of agricultural production. it shows how much the production of agricultural products to a particular enterprise costs. the cost price reflects the qualitative aspect of the economic activities of enterprises: the efficiency of using production resources, the state of technology and organization of production, the introduction of science and advanced experience, the level of economic management. the cost of production is necessary to justify the rational allocation and specialization of agricultural production, to determine its economic efficiency, to establish the level of prices for agricultural products. the purpose of this article is to show ways to reduce the cost of agricultural products, which is one of the most important issues in uzbekistan. this article discusses ways to reduce the cost of production in agriculture and suggests ways to reduce costs in order to improve efficiency in the production of agricultural products Show More ... ... Show Less

  • The Cost
  • Agricultural Products
  • Agricultural Production
  • Cost Of Production
  • Economic Efficiency
МОДЕЛЮВАННЯ ЗМІШАНИХ СТРАТЕГІЙ ІННОВАЦІЙНОГО РОЗВИТКУ ЗАЛІЗОРУДНИХ ПІДПРИЄМСТВ В УМОВАХ РИНКОВИХ ПЕРЕТВОРЕНЬ

the article raises the problem of the need for efficient management of the innovation and investment development of iron ore enterprises in the current difficult conditions of market transformations. a generalization of methodological approaches to improving the management of the balanced strategic innovation development of the iron ore enterprise in the conditions of intensification of the growth of scientific and technological progress taking into account the influence of economic risks. in order to increase efficiency and profitability, a methodological approach has been developed and the toolkit for solving the task of optimizing the economic activity of a large mono-product enterprise has been proposed by finding a solution in mixed innovation strategies that will expand the possibilities of successive optimization of the enterprise's production program from long- term, current to operational planning, intervals of choice of management influences, taking into account general perspective goals of mining x works on the enterprise, taking into account the stochastic nature of the processes of production and economic activity of the iron ore enterprise Show More ... ... Show Less

  • Iron Ore
  • Economic Activity
  • Methodological Approaches
  • Innovation Strategies
  • General Perspective
БЛОКУВАННЯ ТВАРИННИЦЬКИХ БУДІВЕЛЬ З ВИКОРИСТАННЯМ НЕПРИДАТНИХ ЗЕМЕЛЬ У РОСЛИННИЦТВІ

it is established that the construction of large volume buildings on the same site allows you to enter a more effective organization of construction works, which ultimately speeds up commissioning and reduces the costs of skotomesto. multi-storey buildings dairy enterprises has a number of advantages that allow you to use the agricultural and traditional lands, reduces in comparison with one- piece construction built-up area of the complex is 2-5 times (depending on height), reduces the length of engineering networks and communications, reducing capital investment for the improvement allows the use of more efficient industrial methods of construction and installation works, reduce construction period, contributes to the comprehensive mechanization and automation of production processes, greatly reduce the surface of the enclosure, improving heat balance of the premises, allowing you to maximize the capacity of load-bearing reinforced concrete structures improve architectural expressiveness of livestock enterprises, gives you the opportunity to build a strong base of construction industry of large cities and industrial centers.it is established that the planning of enterprises for the production of milk with zabudova building size 42х81 m in a three-storey version with the use of the land landscape, with a gradient 12-18% for 1200 cows provides the cost per head of 20,42 m2, building area of 8.5 m2, milk production per primary production 187,5 tonnes annually and per hectare of development – 2449 tons of milk at the level of profitability 70,74 Show More ... ... Show Less

  • Reinforced Concrete
  • Primary Production
  • Large Volume
  • Production Processes
  • Construction Works
ОСОБЛИВОСТІ ОРГАНІЗАЦІЙНО-ПЕДАГОГІЧНИХ УМОВ ФОРМУВАННЯ ІНДИВІДУАЛЬНОЇ ОСВІТНЬОЇ ТРАЄКТОРІЇ МАЙБУТНЬОГО ВЧИТЕЛЯ МУЗИКИ У ПРОЦЕСІ ПРОФЕСІЙНОЇ ПІДГОТОВКИ

the article defines the issues of the specificity of the structure of the individual educational trajectory of the future music teacher. the algorithm of individualization of the student learning process is considered. the definition of the terms “individual educational trajectory” and “pedagogical condition” is given. the author briefly reveals the organizational and pedagogical conditions for the formation of the individual educational trajectory of future music teachers, in which he emphasizes the improvement and revision of educational programs on the basis of partner collaboration with a student. it also points to the need to maximize the use of organizational ideas of dual education by increasing the elements of practice-oriented education. particular attention is paid to the need to modernize the functions of the teacher-curator through updating the content and principles of the institute of the curator Show More ... ... Show Less

  • The Individual
  • Student Learning
  • Learning Process
  • Educational Programs
  • The Future
ISLAMIC PRINCIPLES AND WORLD PRINCIPLES OF THE STATE

in this article constituting family education based on the islamic religion and keeping its productive perfectly, its systematic, consistency, continuity key results are main factor in islamic rituals its consistency is the process of development of islamic knowledge according to teaching youngsters from simplicity to complexity stages. and its systematic relation is identified with person’s upbringing which is impossible with family education and it is not neglected in our country Show More ... ... Show Less

  • Family Education
  • The State
  • Islamic Religion
  • Main Factor
  • Islamic Rituals
MATHEMATICAL MODEL FOR MANAGEMENT OF THE MUNICIPAL AUTHORITIES

in the presented paper to solve the problem was used the "analytic hierarchy process" method developed by tomas l. saaty. ahp is one of the most popular analytical techniques for complex decision-making problems. in this method a decision-making problem decomposes into a system of hierarchies of objectives, attributes (or criteria), and alternatives. then to obtain optimum solution uses judgements of experts with a special scale for measuring non-quantitative and method of establishing priorities Show More ... ... Show Less

  • Decision Making
  • Mathematical Model
  • Complex Decision
  • Process Method
  • Saaty Ahp
ХИРУРГИЯ ЭКССУДАТИВНЫХ ПЕРИКАРДИТОВ

in the article are presented modern approaches to diagnostics, etiological search and methods of surgical correction of pericardial effusion (pe) of different etiology. pe being the most common disease of the pericardium, often has a secondary nature. the overview of modern literature data is presented about terminology and classification of pe, the possibility of etiological search for the cause of effusion in the pericardial cavity, the main diagnostic methods, as well as the main tasks and methods of pericardial surgical interventions and its indications. based on the analysis of literary sources, we can conclude that the consensus on the clinical and nosological structure, effectiveness and necessity of using various tests and interventions, clinical progression, epidemiology, prognosis and the reasons for the unsatisfactory results of treated pe is actually absent. our analysis indicates the absence of a systematic and differential approach to choice of treatment tactics Show More ... ... Show Less

  • Pericardial Effusion
  • Diagnostic Methods
  • Common Disease
  • Clinical Progression
THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) AND MODERN APPROACH TO ITS INVESTIGATION AND TREATMENT

thrombotic thrombocytopenic purpura (ttp) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ ischemia linked to disseminated microvascular platelet rich-thrombi. ttp is specifically related to a severe deficiency in adamts13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13), the specific von willebrand factor-cleaving protease. adamts13 deficiency is most frequently acquired via adamts13 autoantibodies, but rarely, it is inherited via mutations of the adamts13 gane. the first acute episode of ttp usually occurs during adulthood, with a predominant anti – adamts13 autoimmune etiology. in rare cases, however, ttp begins as soon as childhood, with frequent inherited forms. ttp is 2 – fold more frequent in women, and its outcome is characterized by a relapsing tendency Show More ... ... Show Less

  • Thrombotic Thrombocytopenic Purpura
  • Hemolytic Anemia
  • Thrombotic Microangiopathy
  • Autoimmune Etiology
ОЦІНКА МІЦНОСТІ ЗЧЕПЛЕННЯ СТРИЖНЕВОЇ АРМАТУРИ З БЕТОНОМ

all known hypotheses have three main groups.1 group. the coupling is considered as the result of the friction between the reinforcement and the concrete. analytical dependencies are deduced from the physical side of the phenomenon taking into account the mechanical and physical properties of the materials;2nd group. the nature of the grip is determined by the magnitude and distribution of the mutual shifts q(x) and τ(x) in the reinforcement along the laying is determined by differentiating the experimental data of the displacement curve;3rd group. the analysis uses the distribution diagrams of longitudinal stresses in the reinforcement σ(x) obtained from the experiment. the tension stresses τ(x) are found from the equation of equilibrium, substituting in the expression τ (x) = ƒσ(x), the data are obtained from the experiments Show More ... ... Show Less

  • Experimental Data
  • Displacement Curve
  • Mechanical And Physical Properties
ПОСТТОТАЛИТАРНЫЙ СИНДРОМ В УКРАИНЕ

actual continuity-true to identify the origins of the problems of modern ukraine that will yelp socіal renewal and further progress.the problems of modern ukraine, societies related to the posttotalitarian state, are analysed in the article. process of transformation of the totalitarian mode in democratic runs into the row of problems: economic, defiant dissatisfaction of population; by the danger of recoil in the past from - for the presences of radical political forces; aspiring to national or to territorial sovereignty, from - after multinational composition of population; influences of other states, defeat sovereignty of ukraine Show More ... ... Show Less

  • The Past
  • Territorial Sovereignty
  • Political Forces