Spatialization of Time in the Entorhinal-Hippocampal System

The functional role of the entorhinal-hippocampal system has been a long withstanding mystery. One key theory that has become most popular is that the entorhinal-hippocampal system represents space to facilitate navigation in one’s surroundings. In this Perspective article, I introduce a novel idea that undermines the inherent uniqueness of spatial information in favor of time driving entorhinal-hippocampal activity. Specifically, by spatializing events that occur in succession (i.e., across time), the entorhinal-hippocampal system is critical for all types of cognitive representations. I back up this argument with empirical evidence that hints at a role for the entorhinal-hippocampal system in non-spatial representation, and computational models of the logarithmic compression of time in the brain.

The influence of the positive affective trait on the willingness to act entrepreneurially: The mediating effect of opportunity evaluation

This article extends previous literature on opportunity evaluation by analysing how positive affect influences opportunity evaluation and the subsequent willingness to act entrepreneurially. We draw on two mediational channels (i.e., the affect-to-affect-to-outcome and affect-to-cognition routes) regarding the influence of affect on positive outcomes upon arguments that opportunity evaluation comprises of the cognitive representations of the focal opportunity and of oneself. Specifically, we analyse the mediating effects of the image of the opportunity and self-efficacy in the relationship between positive affect and the willingness to act entrepreneurially. We test our hypotheses on a sample of nascent entrepreneurs participating in training programmes in six Spanish incubators whom were asked to evaluate their own opportunities. Our findings show that positive affect exerts a positive indirect effect through the image of the opportunity, but do not indicate any mediating effect of self-efficacy. These findings may help entrepreneurs understand the affective subjectivity of their opportunity assessments.

Dissociating encoding of memory and salience by manipulating long-term synaptic potentiation

Neural codes are thought to be reorganized during memory formation by long-term potentiation (LTP) of synapses. Here, using a novel approach for selectively blocking LTP, we found that eliminating LTP in hippocampal or striatal circuits only produces limited effects on learning and memory. To reconcile the discrepancy between the large physiological effect of blocking LTP and the absent effect on learning, we studied how LTP impacts neuronal computations in the hippocampus using in-vivo Ca2+-imaging. Contrary to current conceptual frameworks, we found that hippocampal CA1-region LTP is not required for accurate representations of space in hippocampal neurons, but rather endows these neurons with reward- and novelty-coding properties. Thus, instead of driving formation of cognitive maps and memory engrams, CA1-region LTP incorporates salience information into cognitive representations.

Psychology of Dwelling and Visual Appropriations—An Anthropological Application

We find ourselves situated within a world that can be experienced visually, for the first time, in its wholeness. Using conceptual analysis, we intend to show that notions born within the practice of habitation, such as the sense of place, place attachment, and hearth, can help us evaluate the psychological implications of the images of Earth taken from space. We chose a phenomenological approach to human habitation because it allows concepts pertaining to connected and inherently interdisciplinary fields, for instance environmental psychology or human geography, to be reunited under the umbrella of an anthropological interpretation. The sensory and imaginary connotations of the notion of place may be noticed starting from the distinction between space as mathematical abstraction and concrete places being experienced directly. An analysis of the nature of this connection leads to the finding that we actively imagine and reimagine the surrounding world as an unfolding space in which we are constantly attempting to dwell. What is of particular interest for us is the manner in which technologically-mediated visual experience may inspire cognitive representations or may generate profound emotions, such as the attachment to a particular place. Therefore, the value of imagination for the anthropology of habitation is not rendered by its compensatory role, but by its link to ontogenesis. Familiar places, which continue to attract us, are capable of triggering unique imaginary processes, reveries which refer us to the primordial steps of ontogenesis with outmost intensity. The process of subjective appropriation of the world begins with that privileged space of origin specific to each of us, the space which we identify with most intensely. Thus, the psychological impact of the image of Earth from space: we become intensely aware that this planet is our Place within a hostile universe.

Changes of Locomotion Speed Affect Distance Estimations in Virtual Reality

Modern Virtual Reality (VR) applications often use artificial locomotion to allow users to travel distances within VR space that exceed the available space used to transfer real-world and real-time motion into the virtual environment. The locomotion speed is usually not fixed and can be selected dynamically by the user. Due to motion adaptation effects, variations of locomotion speed could affect how distances in VR are perceived. In the context of cartographic VR applications aimed to experience and communicate spatial information, such effects on distance perception could be problematic, because they might lead to distortions in cognitive representations of space acquired via interaction with VR environments. By conducting a VR-based distance estimation study, we demonstrate how changes of artificial locomotion speed affect distance estimations in VR. Increasing locomotion speeds after letting users adapt to a lower locomotion speed led to lower distance estimations and decreasing locomotion speeds led to higher distance estimations. These findings should sensitize VR developers to consider the choice of applied locomotion techniques when a developed VR application is supposed to communicate distance information or to support the acquisition of a cognitive representation of geographic space.

Human ventromedial prefrontal cortex lesions enhance expectation-related pain modulation

Pain is strongly modulated by expectations and beliefs. Research across species indicates that subregions of the ventromedial prefrontal cortex (VMPFC) play a fundamental role in learning and generating predictions about valued outcomes. Consistent with this overarching framework, neuroimaging studies of experimental pain indicate that VMPFC activation tracks expectations of pain relief and statistically mediates expectation-related reductions in responses to painful stimuli across a distributed pain processing network. However, lesion studies in preclinical models and in humans with refractory chronic pain suggest that VMPFC may play a more general role in representing the affective and motivational qualities of pain that contribute to its strong aversive drive. To test whether VMPFC is necessary for pain processing in general, or instead plays a more specific role in the modulation of pain by expectations, we studied responses to experimental heat pain in five adults with bilateral surgical lesions of VMPFC and twenty healthy adults without brain damage.All participants underwent quantitative sensory testing (QST) to characterize pain sensitivity, followed by a pain expectancy task. Participants were instructed that auditory cues would be followed by heat calibrated to elicit low or high pain. Following a conditioning phase, each cue was intermittently paired with a single temperature calibrated to elicit moderate pain. We compared ratings of moderate heat stimuli and subjective expectancy ratings as a function of cue to evaluate whether VMPFC lesions impact cue-based expectancy and expectancy effects on pain intensity and unpleasantness. We also analyzed QST measures to evaluate whether VMPFC lesions were associated with overall shifts in pain sensitivity.Compared to adults without brain damage, individuals with VMPFC lesions reported larger differences in expectations as a function of pain-predictive cues, and stronger cue-based modulation of pain ratings, particularly for ratings of pain unpleasantness. There were no group differences in pain sensitivity, nor in the relationship between pain and autonomic arousal, indicating that the impact of VMPFC lesions is specific to expectancy-based modulation of pain unpleasantness.Our findings suggest that the VMPFC is not essential for basic subjective and physiological responses to painful stimuli. Rather, our findings of significantly enhanced cue- related expectancy effects may suggest that VMPFC plays an important role in updating expectations or integrating sensory information with expectations to guide subjective judgements about pain. Taken together, these results expand our understanding VMPFC’s contribution to pain and highlight the role of VMPFC in integrating cognitive representations with sensory information to yield affective responses.

Intergenerational Contact Experiences and Their Relation to Ageism as a Multidimensional Construct

Research on intergroup contact suggests that negative contact experiences affect cognitive representations such as stereotypes more strongly than positive contact experiences. To comprehensively examine the full effect of intergroup contact, the valence of the contact experience as well as the affective and cognitive dimensions of prejudice should be assessed. In ageism research, previous studies typically focused only on contact of positive valence and were limited to the perspectives of younger individuals on older adults. Primary objective of this study is to examine both positive and negative contact frequency and their relation to affective and cognitive dimensions of ageism from the perspectives of younger adults between the age of 18 and 25 (study 1) and older adults between the age of 60 and 92 (study 2). Consistent with previous research on intergroup contact, our results confirm that both types of contact were similarly predictive of affective facets of prejudice. However, only in study 2 that assessed older adults’ agreement with contemporary stereotypes about young men and women, negative compared to positive contact frequency proved to be a stronger predictor of the cognitive dimension of ageism. Our findings emphasize the importance of focusing on all dimensions of prejudice and highlight the need to consider the perspectives of young and old in ageism research.

Making Cognitive Niches Explicit: On the Importance of External Cognitive Representations in Accounting for Cumulative Culture

Cumulative transmission and innovation are the hallmark properties of the cultural achievements of human beings. Cognitive scientists have traditionally explained these properties in terms of social learning and creativity. The non-social cognitive dimension of cumulative culture, the so-called technical reasoning, has also been accounted for recently. These explanatory perspectives are methodologically individualistic since they frame cumulative and innovative culture in terms of the processing of inner cognitive representations. Here we show that going beyond methodological individualism could facilitate an understanding of why some inventions are disseminated in a stable form and constitute the basis for further modifications. Drawing on three cases of cognitive history of prominent achievements of Antiquity, i.e., Homerian epics, Euclidean geometry, and Roman law, we investigate which properties of cognitive artifacts shaped cognitive niches for modifying original cognitive tasks or developing new ones. These niches both constrained and enabled the cognitive skills of humans to promote cumulative culture and further innovations. At the same time, we claim that “wide cognition,” incorporating both intracranial resources and external cognitive representations, constitutes a platform for building explanations of cognitive phenomena developing over a historical time scale.