This paper investigates the technical resources of cooperation of industry, government and university, and how industrial value chains (IVC) in e-tourism industry develop in such collaboration. First, the chance of cooperation between small and medium enterprises (SMEs) in tourism industry and information technology developers were discovered inside the national industry policies of Taiwan, and local technological universities could play a key role inside as an official resource importer. Then, theoretical feasibility of industry-government-university cooperation in e-tourism and IVC were testified to build the core concept of e-tourism IVC model with cooperation of industry, government and university. Furthermore, based on prospective framework in e-tourism, the research team, consisting of professionals in various fields, put the concept into practice by endeavoring to collaborate with enterprises in tourism and information and communication technology (ICT) industry. After complying with requirements of grant applying programs, the team acquired funds of 570,000 NTD from Ministry of Education (MOE), companies and universities, making this cooperation model preliminarily practical. As stated above, e-tourism IVC model with cooperation of industry, government and university is an applicable university-industry cooperation (UIC) model technological universities can utilize to enhance competitiveness of ICT and tourism industries, as well as SMEs.