Relative Impact and Analysis of Composition of Goat Milk by Stall-Feeding System and Rearing with Grazing System of Goats

In many regions of the world, goat milk and its milk products have played a major role in economic viability, particularly in developing countries like India. In terms of getting milk products high in minerals and other protein, the importance of free grazing still prevails and is preferred over stall feeding, but both ways are good in general. With the importance of the above in mind, an approach has been taken in the current study to compare the yield of milk from goats using a stall-feeding system and a free grazing system. Our findings show that milk minerals such as Calcium, Potassium, Magnesium, and Sodium are higher in stall-feeding goat systems than in free grazing systems because stall-feeding provides a computed ration – Minerals, Common salt, mineral mixture, concentrate feeding, feed additives, and feed supplement. As a result, milk minerals are higher in stall-feeding goat systems than in free grazing goat systems. Lactose levels are higher in stall-feeding systems than in open grazing systems because leguminous feeds like as lucerne and bersim grasses, as well as green forages, are used. Because they graze freely in the environment and consume various types of feeds, fat percentage is higher in the free grazing system of goats than in the stall-feeding system. Since stall-feeding systems provide feed supplement and concentrate feeding, fat soluble vitamins are higher in stall-feeding systems than in free grazing systems, which is why fat-soluble vitamins are higher in stall-feeding systems of goats.

Plasma glucagon-like peptide-1 responses to ingestion of protein with increasing doses of milk minerals rich in calcium

A high dose of whey protein hydrolysate fed with milk minerals rich in calcium (Capolac®) results in enhanced glucagon-like peptide-1 (GLP-1) concentrations in lean individuals, however the effect of different calcium doses ingested alongside protein is unknown. The present study assessed the dose response of calcium fed alongside 25 g whey protein hydrolysate on GLP-1 concentrations in individuals with overweight/obesity. Eighteen adults (mean ± SD: 8M/10F, 34 ± 18 years, 28.2 ± 2.9 kg∙m−2) completed 4 trials in a randomised, double-blind, crossover design. Participants consumed test solutions consisting of 25 g whey protein hydrolysate (CON), supplemented with 3179 mg (LOW), 6363 mg (MED), or 9547 mg (HIGH) Capolac® on different occasions, separated by at least 48 hours. The calcium content of test solutions equated to 65, 892, 1719 and 2547 mg, respectively. Arterialised-venous blood was sampled over 180 min to determine plasma concentrations of GLP-1TOTAL, GLP-17-36amide, insulin, glucose, non-esterified fatty acids (NEFA), and serum concentrations of calcium and albumin. Ad libitum energy intake was measured at 180 min. Time-averaged incremental area under the curve (iAUC) for GLP-1TOTAL (pmol·L−1·min−1) did not differ between CON (23 ± 4), LOW (25 ± 6), MED (24 ± 5), and HIGH (24 ± 6). Energy intake (kcal) did not differ between CON (940 ± 387), LOW (884 ± 345), MED (920 ± 334), and HIGH (973 ± 390). Co-ingestion of whey protein hydrolysate with Capolac® does not potentiate GLP-1 release in comparison to whey protein hydrolysate alone. The study was registered at clinical trials (NCT03819972).

Cow’s Milk Processing—Friend or Foe in Food Allergy?

Cow’s milk (CM) is an integral part of our daily diet starting in infancy and continuing throughout our lifetime. Its composition is rich in proteins with a high nutritional value, bioactive components, milk minerals including calcium, and a range of immunoactive substances. However, cow’s milk can also induce a range of immune-mediated diseases including non-IgE-mediated food allergies and IgE-mediated food allergies. Cow’s milk allergens have been identified and characterized and the most relevant ones can be assigned to both, the whey and casein fraction. For preservation a range of processing methods are applied to make cow’s milk and dairy products safe for consumers. However, these methods affect milk components and thus alter the overall immunogenic activity of cow’s milk. This review summarizes the current knowledge on cow’s milk allergens and immunoactive substances and the impact of the different processes up- or downregulating the immunogenicity of the respective proteins. It highlights the gaps of knowledge of the related disease mechanisms and the still unidentified beneficial immunomodulating compounds of cow’s milk.

289 Effects of dietary Zn on ewe milk minerals and somatic cell count

The objectives of the current study were to evaluate the effects of dietary Zn fed at approximately 3 times NRC recommendations on milk Zn concentrations and mammary health. Within Rambouillet (WF) and Hampshire (BF) breeds, ewes were ranked by BW and randomly assigned down the rank into 2 treatment groups: Control (n = 45, 37 mg Zn/kg DM) and Zn treatment (n = 44, 113 mg Zn/kg DM). Treatments were delivered via a ZnSO4-fortified alfalfa pellet fed at a rate of 0.45 kg/d DM from a RFID-activated automated feeder from approximately 6 wk before to 4 wk after lambing. Ewe milk was collected twice weekly, and analyzed for mineral content (d 0, 10, and 30 of lactation) and somatic cell count (SCC; d 3–5, 6–9, 10–12, 13–16, 17–19, 20–23, 24–26, 27–29, or 30–32). Single-bearing ewes had greater Ca, Mg, and P (P ≤ 0.04) than multiple-bearing ewes. Day of lactation influenced milk Mg, P, and Zn (P < 0.01), and values generally decreased as lactation progressed. Milk Zn was 1.7-fold greater (P < 0.01) for Zn treatment than Control ewes. Milk Ca, Mg, and P were greater for Control than Zn treatment (P ≤ 0.02) ewes. A breed × litter size effect was detected for LogSCC (P = 0.02). Single-bearing WF ewes had lower LogSCC than multiple-bearing WF ewes (5.36 ± 0.09 vs 5.74 ± 0.07; P < 0.01) but litter size did not affect BF ewe LogSCC (5.80 ± 0.08 vs 5.79 ± 0.09; P = 0.92). Day of lactation impacted ewe SCC (P < 0.01), with peak SCC between d 6 and 9, which began to decline as lactation progressed. In conclusion, dietary Zn above NRC recommendations increased milk Zn.

424 WS Young Scholar Talk PHD: Effect of increasing dietary zinc during late gestation and early lactation on ewe and lamb body weights, serum and milk minerals, and somatic cell count

The objectives of the current research are to quantify the effects that increased dietary Zn during late gestation and early lactation has on ewe and progeny body weights, serum and milk minerals, and somatic cell count. Within Rambouillet (WF) and Hampshire (BF) breeds, ewes were ranked by BW and randomly assigned down the rank into 1 of 2 treatment groups: Control (n = 34, 37 mg Zn/kg DM, ≈1×NRC) and Zn treatment (n = 37, 113 mg Zn/kg DM, ≈3×NRC). Treatments were delivered via a ZnSO4-fortified alfalfa pellet fed at a rate of 0.45 kg/d DM from a RFID-activated automated feeder from d 108 ± 10 of gestation to d 30 post-lambing. Ewe BW were recorded at d 0, 29, lambing, 30 post-lambing, and weaning. Lamb BW was recorded at lambing, d 15, 30, and weaning. Serum samples were taken from ewes and lambs at 18 ± 4 h post-lambing and analyzed for mineral concentrations. Maternal trace mineral transfer efficiency were calculated by dividing lamb serum values by their respective dam’s serum value and expressed as a percentage. Ewe milk was collected twice weekly. Milk was analyzed for mineral content (d 0, 10, and 30 of lactation) and SCC (d 3–5, 6–9, 10–12, 13–16, 17–19, 20–23, 24–26, 27–29, or 30–32). Ewe and lamb BW was not influenced by Zn treatment (P > 0.19). Ewe serum Zn and maternal transfer efficiency did not differ between control and Zn treatment ewes (P ≥ 0.47). There was a treatment × breed type interaction for lamb serum LogZn (P = 0.04), where BF lambs within Zn treatment had greater serum LogZn (0.63 ± 0.32) than WF lambs (-0.37 ± 0.27; P = 0.04), but breeds did not differ within lambs in the Control treatment group. Milk Ni and Zn was greater for Zn treated ewes than control ewes (P < 0.01), but Mg and P concentrations were greater for control ewes (P ≤ 0.02). Control and Zn treated ewes did not differ in LogSCC through the first 30 d of lactation (P = 0.68) nor did they differ at weaning (P = 0.48). White face and BF ewes LogSCC did not differ at weaning (P = 0.09), but for the first 30 d of lactation BF (5.79 ± 0.06) had greater LogSCC than WF ewes (5.54 ± 0.06; P < 0.01). Day of lactation impacted ewe SCC (P < 0.01), with peak SCC between d 6 and 9 which began to decline as lactation progressed. Current Zn recommendations appear to be adequate for ewe and lamb growth during late gestation and early lactation, but results suggest litter size and breed nuances. Milk Zn is also increased with dietary Zn above NRC recommendations, while further interactions with milk Ni, Mg, and P occur. Additionally, longitudinal values of SCC throughout lactation may inform preventative intervention strategies for cases of sub-clinical mastitis since peak SCC is within the first 9 d post-lambing.