Impact of Land-use Change on Dengue Hemorrhagic Fever in Kolaka District, Southeast Sulawesi Province, Indonesia

Land use change is contributing to the emergence of zoonotic diseases in the community. And can cause an increase in the spread of the virus through arthropods. This study aimed to determine the association of land use factors and dengue hemorrhagic fever in Kolaka District, Southeast Sulawesi Province, Indonesia. The secondary data obtained from various governments of Indonesia were used for this study. Data of dengue hemorrhagic fever from Ministry of Health of Republic Indonesia. Land use data is derived from the classification of Citra Landsat 8 on a scale of 1: 250,000 from 2010 to 2020. The Spearman rank correlation test was used to examine the relationship between land-use change and the incidence rate of dengue hemorrhagic fever. The results of this study In Period 2010-2015 is a correlation between Agriculture with dengue hemorrhagic fever ( α = 0.812, p <0.05), and water bodies with α =0.812. The area of agricultural land is increasing every year; in 2010, only 3.32% increase to 51.08% in 2015. Furthermore, in period 2016-2020 is a correlation between Forest with dengue hemorrhagic fever (α = 0.900, p <0.05), and Settlement (α = -0.900, p <0.05). Our findings could be used to improve the understanding of land-use change and dengue hemorrhagic fever in the Kolaka district and provide information on land use that does not damage the environment.

Review on Mapping of Tasks to Resources in Cloud Computing

Resource allocation and scheduling algorithms are the two essential factors that determine the satisfaction of cloud users. The major cloud resources involved here are servers, storage, network, databases, software and so on based on requirements of customers. In the competitive scenario, each service provider tries to use factors like optimal configuration of resources, pricing, Quality of Service (QoS) parameters and Service Level Agreement (SLA) in order to benefit cloud users and service providers. Since, many researchers have proposed different scheduling algorithms and resource allocation strategies, it becomes a cumbersome task to conclude which ones really benefit customers and service providers. Hence, this paper analyses and presents the most relevant considerations that would help the cloud researchers in achieving their goals in terms of mapping of tasks to cloud resources.

Insecticide-treated net (ITN) use, factors associated with non-use of ITNs, and occurrence of sand flies in three communities with reported cases of cutaneous leishmaniasis in Ghana

Background The insecticide treated bed net (ITN) has been proven for malaria control. Evidence from systematic review also suggests benefits of ITN roll out in reducing the incidence of cutaneous leishmaniasis (CL) and other vector borne diseases. Methods Using a community-based cross-sectional study design, ITN use, factors associated with non-use of ITNs, and occurrence of sand flies were investigated in three communities with reported cases of CL in the Oti region of Ghana. Results A total of 587 households comprising 189 (32.2%), 200 (34.1%), and 198 (33.7%) households from Ashiabre, Keri, and Sibi Hilltop communities with de facto population of 3639 participated in this study. The proportion of households that owned at least one ITN was 97.1%. The number of households having at least one ITN for every two members was 386 (65.8%) and 3159 (86.8%) household population had access to ITN. The household population that slept in ITN the night before this survey was 2370 (65.1%). Lack of household access to ITN (AOR = 1.80; CI: 1.31, 2.47), having a family size of more than 10 members (AOR = 2.53; CI: 1.20, 4.24), having more than 10 rooms for sleeping in a household (AOR = 10.18; CI: 1.28, 81.00), having 2–4 screened windows (AOR = 1.49; CI: 1.00, 2.20), and having 8–10 screened windows (AOR = 3.57; CI: 1.25, 10.17) were significantly associated with increased odds of not sleeping in ITN the night before the survey. A total of 193 female sand flies were trapped from various locations within the study communities. Conclusions Factors associated with ITN non-use such as lack of household access to ITN should be incorporated into future efforts to improve ITN use. Species of sand flies and their potential vectorial role in the study communities should also be investigated.

Does all the evidence say that insulin analogues are more effective than human insulins?

Currently, a large amount of data has been accumulated to compare recombinant human insulin with insulin analogues, including meta-analyzes of comparative efficacy and safety, as well as cost-effectiveness data and data on the possible carcinogenicity of new products. Insulin treatment is a necessity for some people with diabetes mellitus (DM) due to the need to maintain optimal blood glucose levels. The authors emphasize the need to keep in mind that new insulin drugs are much more expensive, which may limit their use. Factors such as the effectiveness of treatment, its safety, and patient satisfaction should be taken into account when deciding on the choice of therapy, but the cost of treatment cannot be ignored, given that it is usually reimbursable from the budget. In this regard, insulin therapy should be individually selected taking into account the needs of patients, treatment goals, safety, and cost. The authors propose an analysis of these data on the feasibility of using insulin analogues in comparison with recombinant human insulin for patients with type 1 diabetes and patients with type 2 diabetes and their effectiveness in both types of diabetes. A reasonable policy for the use of insulin therapy should be developed based on available clinical data based on comparative studies in different groups of diabetics and comprehensive analysis of economic data. The feasibility of a new drug should be evaluated and regularly reviewed in light of the practical results of its use in clinical practice. It is also necessary to regularly conduct a retrospective economic analysis to assess the pharmacoeconomic benefits. All of these steps should assist decision-makers and regulators in implementing effective national programs to develop new effective insulin procurement systems.

INDICATORS OF SA-19 “GRISON” ANTI-AIRCRAFT GUN MISSILE SYSTEM EFFICIENCY WHEN FIRING AT NONTYPICAL TARGETS OF THE ROCKET AND ARTILLERY WEAPONS

In modern conditions of combat use the SA-19 “Grison” anti-aircraft gun missile system fires at small targets (drones) and typical targets (helicopters and attack aircraft), so a number of problems arise. In particular, they include: finding the value of the probabilities of hitting the target with n shots and one shot; assessing the effectiveness of the SA-19 “Grison” platoon‟s concentrated fire on a single target; estimating errors of missile guidance and warhead detonation system; estimating the values of conditional probabilities of hitting a target with a single missile, depending on the value of particular mishit. When calculating the slant range to the far edge of the SA-19 “Grison” weapon's kill zone under different conditions of use, factors that reduce these ranges should be taken into account. An analysis of the main studies and publications presented in [1-9] does not make it possible to determine the performance of missile and artillery weapons in shooting at small-size targets. This literature provides general approaches to solving this problem. The purpose of this article is to develop a model for calculating the values of conditional probabilities of destruction of small targets, to form the best options for repelling an enemy‟s air strike, as well as to justify the general directions of improvement of weapon‟s elements.

USE OF PRELACTEAL FEEDS- STUDY IN TRADITION

Objective: To find the types and frequency of prelacteal use, factors influencing their use and its impact on breastfeeding. Study Design: Cross-sectional study. Place and Duration of Study: Fatima Memorial Hospital, Lahore, Pakistan from Jul to Dec 2019. Methodology: In the study, mothers and female attendants of newborn babies were interviewed following a specific questionnaire. The given answers were recorded and captured data about socio-demographics, knowledge, attitude and actual practices of mothers and families related to use of prelacteals. The results were analysed using SPSS 22. Results: We interviewed 1601 mothers and female attendants of neonates. The mean age was 32.3 ± 8.2 years. Most of the females were married (1211, 75.6%) and resided in Lahore (1281, 80%). About one third, 581 (36.3%) were either illiterate or had inadequate schooling. Two-thirds (1000, 62.5%) of women wanted to give some prelacteal feed soon after birth. Honey was the most the commonest choice (in 722, 45.1%), seconded by ghutti (107, 6.7%). Most females (1467, 91.6%) wanted to give colostrum, and 1552 (96.9%) would breastfeed the baby. 1221 (75.2%) wanted to start mother-feed immediately or within 2 hours of birth. Conclusion: The use of prelacteal is common in Pakistan culture. A consistent effort is needed to counter the unsafe prelacteal use.

A prognostic model for patients with lymphoma and COVID-19: a multicentre cohort study

Lymphoma represents a heterogeneous hematological malignancy (HM), which is characterized by severe immunosuppression. Patients diagnosed of coronavirus disease (COVID-19) during the course of HM have been described to have poor outcome, with only few reports specifically addressing lymphoma patients. Here, we investigated the clinical behaviour and clinical parameters of a large multicenter cohort of adult patients with different lymphoma subtypes, with the aim of identifying predictors of death. The study included 856 patients, of whom 619 were enrolled prospectively in a 1-year frame and were followed-up for a median of 66 days (range 1-395). Patients were managed as outpatient (not admitted cohort, n=388), or required hospitalization (n=468), and median age was 63 years (range 19-94). Overall, the 30- and 100-days mortality was 13% (95%CI 11-15%) and 23% (95%CI 20-27%), respectively. Anti-lymphoma treatment, including anti-CD20 containing regimens, did not impact on survival. Patients with Hodgkin's lymphoma had the more favourable survival, but this was partly related to significantly younger age. The time interval between lymphoma diagnosis and COVID-19 was inversely related to mortality. Multivariable analysis recognized 4 easy-to-use factors (age, gender, lymphocyte, and platelet count) that were associated with risk of death, both in the admitted and in the not-admitted cohort (HR 3.79 and 8.85 for the intermediate and high-risk group, respectively). Overall, our study shows that patients should not be deprived of the best available treatment for their underlying disease, and indicates which patients are at higher risk of death. This study was registered with ClinicalTrials.gov, NCT04352556.

Effects of Land Use on Land Surface Temperature: A Case Study of Wuhan, China

In this study, we aim to understand the impact of land use on the urban heat island (UHI) effect across an urban area. Considering the case study of Wuhan, China, land use factors and land surface temperatures (LSTs) of 589 planning management units were quantified in order to identify the spatial autocorrelation of LST, which indicated that a traditional regression would be invalid. By investigating the relationships between land use factors and the LST in summer, based on spatial regression models including the spatial lag model and the spatial error model, four conclusions were derived. First, the spatial error model effectively explains the relationships between LST and land use factors. Second, the impact on LST of the percentage of industrial areas is significant even though the impacts of land cover and building-group morphology indicators are combined, indicating that anthropogenic heat emission of industrial production contributes to high LSTs. Third, the relationship between the percentage of commercial area and LST is significant in the Pearson correlation analysis and traditional regression models, while not significant in spatial error model, suggesting that the urban heat environment of a commercial area is determined by the land use factors of the surrounding area. Fourth, the UHI effect in industrial and commercial areas could be precisely mitigated by not locating industrial areas beside residential areas, and setting up buffer zones between commercial areas and surrounding traditional residential areas. Overall, the results of this study innovatively deepen the understanding of the impact of the percentage of different urban land use types on the urban heat environment at the scale of planning management units, which is conducive to formulating precise regulation measures for mitigating UHI effects and improving public health.