physiological monitoring
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Exploration ◽  
2021 ◽  
pp. 210033
Author(s):  
M. A. Parvez Mahmud ◽  
Trinny Tat ◽  
Xiao Xiao ◽  
Partho Adhikary ◽  
Jun Chen

2021 ◽  
Vol 65 (2) ◽  
Author(s):  
Jian He ◽  
Sen Li ◽  
Xiaojuan Hou ◽  
Yongjun Zhou ◽  
Hao Li ◽  
...  

Nano Energy ◽  
2021 ◽  
pp. 106787
Author(s):  
Tao Wang ◽  
Shuyao Li ◽  
Xingling Tao ◽  
Qi Yan ◽  
Xingling Wang ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0259559
Author(s):  
Ryan P. Sixtus ◽  
Cholawat Pacharinsak ◽  
Clint L. Gray ◽  
Mary J. Berry ◽  
Rebecca M. Dyson

Background Non-invasive physiological monitoring can induce stress in laboratory animals. Sedation reduces the level of restraint required, thereby improving the validity of physiological signals measured. However, sedatives may alter physiological equilibrium introducing unintended bias and/or, masking the experimental outcomes of interest. We aimed to investigate the cardiorespiratory effects of four short-acting sedatives in juvenile guinea pigs. Method 12 healthy, 38 (26–46) day-old Dunkin Hartley guinea pigs were included in this blinded, randomised, crossover design study. Animals were sedated by intramuscular injection using pre-established minimum effective doses of either alfaxalone (5 mg/kg), diazepam (5 mg/kg), ketamine (30 mg/kg), or midazolam (2 mg/kg) administered in random order with a minimum washout period of 48 hours between agents. Sedative depth, a composite score comprised of five assessment criteria, was observed every 5-min from dosing until arousal. Physiological monitoring of cardiorespiratory status included measures of heart rate, blood pressure, respiratory rate, and peripheral microvascular perfusion. Results Ketamine and alfaxalone were most effective in inducing stable sedation suitable for physiological monitoring, and diazepam less-so. Midazolam was unsuitable due to excessive hypersensitivity. All sedatives significantly increased heart rate above non-sedated control rates (P<0.0001), without altering blood pressure or microvascular perfusion. Alfaxalone and ketamine reduced respiratory rate relative to their control condition (P<0.0001, P = 0.05, respectively), but within normative ranges. Conclusion Ketamine and alfaxalone are the most effective sedatives for inducing short duration, stable sedation with minimal cardiorespiratory depression in guinea pigs, while diazepam is less-so. However, alfaxalone is the most appropriate sedative for longitudinal studies requiring multiple physiological timepoints.


2021 ◽  
pp. 307-319
Author(s):  
D. Bustos ◽  
J. C. Guedes ◽  
Mário Vaz ◽  
J. Torres Costa ◽  
R. J. Fernandes ◽  
...  

2021 ◽  
pp. 293-305
Author(s):  
D. Bustos ◽  
J. C. Guedes ◽  
J. Santos Baptista ◽  
Mário Vaz ◽  
J. Torres Costa ◽  
...  

Nano Energy ◽  
2021 ◽  
pp. 106755
Author(s):  
Yiming Liu ◽  
Xingcan Huang ◽  
Jingkun Zhou ◽  
Jian Li ◽  
Sina Khazaee Nejad ◽  
...  

Sensors ◽  
2021 ◽  
Vol 21 (21) ◽  
pp. 7249
Author(s):  
Denisse Bustos ◽  
Joana C. Guedes ◽  
João Santos Baptista ◽  
Mário P. Vaz ◽  
José Torres Costa ◽  
...  

The emergence of physiological monitoring technologies has produced exceptional opportunities for real-time collection and analysis of workers’ physiological information. To benefit from these safety and health prognostic opportunities, research efforts have explored the applicability of these devices to control workers’ wellbeing levels during occupational activities. A systematic review is proposed to summarise up-to-date progress in applying physiological monitoring systems for occupational groups. Adhering with the PRISMA Statement, five databases were searched from 2014 to 2021, and 12 keywords were combined, concluding with the selection of 38 articles. Sources of risk of bias were assessed regarding randomisation procedures, selective outcome reporting and generalisability of results. Assessment procedures involving non-invasive methods applied with health and safety-related goals were filtered. Working-age participants from homogeneous occupational groups were selected, with these groups primarily including firefighters and construction workers. Research objectives were mainly directed to assess heat stress and physiological workload demands. Heart rate related variables, thermal responses and motion tracking through accelerometry were the most common approaches. Overall, wearable sensors proved to be valid tools for assessing physiological status in working environments. Future research should focus on conducting sensor fusion assessments, engaging wearables in real-time evaluation methods and giving continuous feedback to workers and practitioners.


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