dental infections
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Author(s):  
Samar A. Bamofleh ◽  
Mohammed S. Almuammar ◽  
Aljawhara I. Bin Osseil ◽  
Roaa A. Alorf ◽  
Sultan M. Alqhtani ◽  
...  

Although there have been many advances in the medical field regarding disease control and management, it has been demonstrated that certain diseases and infections still represent a significant challenge. For example, the presence of oral biofilms indicates the virulence of the underlying infection in different dental infections diseases, including peri-implantitis, periapical periodontitis, periodontitis, gingivitis, and dental caries. We have discussed various mechanical, chemical, and biological modalities that can be applied to control biofilms and limit plaque formation and secondary caries. Although physical brushing might be efficacious in cleaning, evidence indicates that it cannot eradicate the underlying bacteria. Accordingly, using biological and chemical materials is essential to achieve adequate disinfection and enhance the outcomes. Many modalities have been proposed in the literature, such as nanomaterials, organic compounds such as arginine, dietary substances, and the various chemical oral cleansers discussed in the current study. Bacteriophages are also promising in this context. However, they need further exploration regarding their efficacy and safety. In addition, resistance against these compounds is a serious issue and needs to be addressed in future research.


Author(s):  
Suhael Ahmed ◽  
Nada Mohamed Abdelfattah Aly Elkholy ◽  
Amna Alghamdi ◽  
Sarah Aedh Alshehri ◽  
Khalid M Alanazi ◽  
...  

Bacterial infections are common in dental and oral clinical practice. It is been estimated that about 10% of total antibiotic prescriptions are related to dental infections. Combination of amoxicillin-clavulanate and plain amoxycillin is the most commonly used drug by dentists across the world. Three general considerations were recognized in this literature review—Empirical antibiotic prescription by dentists without a culture test; concomitant prescription of antibiotics with non-steroidal anti-inflammatory drugs which may ultimately affect the bioavailability of the former drug; and the increased antimicrobial resistance amongst oral pathogens. Since decades, antibiotics have been prescribed for the treatment of odontogenic infections and non-odontogenic oral infections, and for focal infections and sepsis prophylaxis. Renal failure, liver failure, and pregnancy are situations that require special attention when considering an antibiotic prescription. This review attempted to contribute to the rational use and abuse of antibiotics while focusing on the general characteristics of these drugs.


2021 ◽  
Vol 2 (6) ◽  
pp. 25-28
Author(s):  
Sahar Kadri ◽  
Dorsaf Touil ◽  
Yosri Abdmouleh ◽  
Latifa Hammouda ◽  
Fatma Hannachi ◽  
...  

Diabetic ketoacidosis (DKA) is a common complication of type I and occasionally type II diabetes mellitus. Patients with DKA require intensive multidisciplinary care involving dental surgeons and endocrine physicians in a hospital setting. The association between diabetes mellitus and oral infections is very common and infection is a well-recognized trigger of DKA. Yet very few cases of DKA secondary to dental infections have been reported in the literature. We, herein, report an interesting case of a pediatric patient presenting with ketoacidosis secondary to acute cervical adenophlegmon of dental origin.


Author(s):  
Rosa Roemers ◽  
Aminata I. Sesay ◽  
Musa G. Sesay ◽  
Jan Henk Dubbink ◽  
Heleen M. Koudijs ◽  
...  

Prevalence data on severe dental infections is scarce, particularly for low-income countries. Patients with dental abscess complications who presented from September 2020 until December 2020 in two hospitals in Tonkolili District, Sierra Leone, were included into this case series. We report on a total of 20 patients, median age 28 years, with severe complications of dental abscesses, with a mortality rate of 45%. This case series illustrates the severity of the dire consequences of the absence of access to basic dental and oral healthcare.


Antibiotics ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1419
Author(s):  
Gabriella Di Di Giuseppe ◽  
Raffaele Lanzano ◽  
Armando Silvestro ◽  
Francesco Napolitano ◽  
Maria Pavia

Background: This study explored the antimicrobial prescribing pattern for upper respiratory tract and dental infections in prisoners in Italy, with specific attention paid to the appropriateness of indication and its potential determinants. Methods: This investigation was conducted through the consultation of clinical records of adult male inmates in a prison in the south of Italy. Results: Prescription of antimicrobials for upper respiratory tract infections ranged from 41.9% in influenza diagnoses to 88% in pharyngitis diagnoses, with high prevalence also for bronchitis (73.5%) and common cold (57.7%), and those for dental infections ranged from 82% in pulp necrosis and symptomatic apical periodontitis/pulp necrosis and localized acute apical abscess diagnoses, to 85.7% in symptomatic irreversible pulpitis with or without symptomatic apical periodontitis diagnoses. The most frequently prescribed antimicrobial was amoxicillin and clavulanic acid (33.8%), followed by amoxicillin (26.5%), macrolides (19.8%) and third-generation cephalosporins (7.9%). The overall antimicrobial overprescription was 69.4%, whereas an antimicrobial prescription was provided in all 52 cases in which it was indicated. The inappropriate antimicrobial prescriptions were significantly less likely for bronchitis, influenza and symptomatic irreversible pulpitis with or without symptomatic apical periodontitis compared to common cold/pharyngitis/rhinosinusitis, and when the antimicrobial prescription was provided by medical specialists compared to prison physicians, whereas antimicrobial overprescriptions without indications were significantly more frequent in patients with underlying chronic clinical conditions. Conclusions: A concerning widespread practice of inappropriate antimicrobial prescriptions in prisoners was found. Diagnoses-specific monitoring of antimicrobial use and prison-focused antimicrobial stewardship policies are strongly needed.


2021 ◽  
Vol 15 (10) ◽  
pp. 2656-2659
Author(s):  
Saood Khan Lodhi ◽  
Saroosh Ehsan ◽  
Malik Ali Hassan Sajid ◽  
Adeela Rafique ◽  
Mehak Fatima Khan

Background: Odontogenic infections are one of the main causes of patients visit to a dental office. Antibiotics are magical drugs that have revolutionized the 20th Century in their ability to treat infectious diseases, increasing the life expectancy of individuals. Antibiotics prescription is a common practice among dental professionals and according to an estimate by Centre for Disease Control (CDC) and American Dental Association (ADA), over prescription of antibiotics is seen in 30-50% of the cases. Aim: To assess and compare (no comparison) the antibiotic prescription pattern among general dentists and specialty dentists in Lahore, Pakistan. Methodology: A cross sectional survey was conducted amongst dentists working in the teaching institutions and in the private clinics of Lahore. A pre-piloted questionnaire survey adopted from Jagan et al with slight modifications was used. In this descriptive study 300 practicing dentists were selected using consecutive sampling with a 5% level of significance and margin of error Results: Total 300 filled questionnaires were collected. Almost 84% of the dentists were less than 30 years old while 13% were between 31-40 years old. Of the participants 65.3% were females and 34.7 percent were males. Dental infections associated with gross swelling or associated with closure of the eye were the most common reasons for prescription of antibiotics. Almost 62% of the dentists would give antibiotic if any delay in treatment is anticipated. Almost 50% of the dentists would prescribe antibiotics for periapical abscess and cellulitis. Conclusion: There is a trend towards over prescription of antibiotics by dentists without following the standard guidelines. Emphasis on the correct prescription strategies of antibiotics at the undergraduate level and more awareness should be created as continuing dental education programs for practicing dentists. Keywords: Antibiotics, Dentists, Prescription Pattern.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Neeta Patel ◽  
Akshayraj Langaliya ◽  
Shikha Kanodia ◽  
Aravind Kumbhar ◽  
Aastha Buch ◽  
...  

Paraesthesia of the mental nerve can occur due to various etiological factors. Rarely, dental infections can cause paraesthesia. However, this article discusses two cases of endodontic etiology in the mental nerve region as a causative factor for paraesthesia. In the first case, the patient had severe pain localized to his right mandible, with numbness of his lower lip. Endodontic treatment led to quick regression and resolution of paraesthesia. In the second case, a patient who was referred for retreatment of a mandibular second premolar infection developed profound paraesthesia in the region of the mental nerve distribution following prior therapy. Possible mechanisms responsible for periapical infection-related paraesthesia are discussed here. CBCT imaging may be useful in the diagnosis and management of such conditions.


2021 ◽  
Vol 15 (9) ◽  
pp. 2833-2836
Author(s):  
Sarah Salim ◽  
Syed Zuhair Mehdi ◽  
Zainab Motiwala ◽  
Hoor ul Ain Iqbal

Objective: The aim of this study is to compare the outcomes of amoxicillin and cephedrine in oral and dental infections. Study Design: Observational/ Comparative study Place and Duration: Riphah International University, Almizan Campus, Rawalpindi/ Nayab Dental Clinic Rawalpindi. January 2021 to Aug 2021. Methods: Total one hundred and fifty patients of both genders were presented in this study. Demographically detailed of included patients age, sex, cause of infection, residency and education status were calculated after taking informed written consent. Patients had oral and dental infection and did not receive any treatment yet were included. Patients were equally categorized into two groups. Group A had 75 patients and received 500mg amoxicillin while group B had 75 patients treated with 500mg cephredine thrice a day for 5 days. Post-treatment effectiveness among both groups was assessed and compared. SPSS 22.0 version was used to analyze the complete data. Results: There were 40 (53.3%) males and 35 (46.7%) females in group A while in group B 38 (50.7%) males and 37 (49.3%) females. Mean age in group A was 34.13±12.42 years and in group B mean age was 35.04±11.31 years. 100 (66.7%) cases were from urban area (50 in each group). 88 (58.7%) patients were literate (44 in each group). Gingivitis was found in 33 (44%) cases in group A and 35 (46.7%) in group B while frequency of periodontitis was 37 (56%) in group A and 40 (53.2%) in group B. Smoking was the most common cause of infection followed by compromised oral hygiene and diabetes. Post treatment frequency of effectiveness in group B was higher among 63 (84%) cases as compared to group A. Frequency of adverse outcomes stomach upset, diarrhea and dizziness were lower in group B. Change of dose frequently noted in group A among 15 (20%) cases as compared to group B 8 (10.7%). Conclusion: We concluded in this study that use of antibiotics in cure of dental and oral infections were effective and useful but amoxicillin was significantly superior to cephredine with less number of adverse outcomes and higher frequency of germs controlled. Keywords: Dental Infection, Amoxicillin, Cephredine, Gingivitis, Periodontitis


Author(s):  
Jeet Patel ◽  
Rebecca T. Le ◽  
Dalys Haymes ◽  
Dinesh Rao ◽  
Peter Fiester ◽  
...  
Keyword(s):  

2021 ◽  
Vol 25 (2) ◽  
pp. 122-128
Author(s):  
Tugba Yigit ◽  
Sibel Ezberci ◽  
Burcu Gucyetmez Topal

Summary Background/Aim: The purpose of this study was to investigate the antibiotic prescribing patterns for the treatment of paediatric oral infection, dental trauma and prophylaxis among dentists in Turkey. Material and Methods: A total of 206 paediatric dentists, including general dentists, paediatric dentists and specialist dentists, participated in this cross-sectional study. The questionnaire included questions about the number of paediatric patients treated and antibiotics prescribed, the most commonly prescribed antibiotic for oral infections and the clinical conditions under which antibiotics were prescribed. The participants’ ages, workplaces and professional experience were also evaluated. Results: The majority of the participants were paediatric dentists (45.1%) and general dentists (42.7%). For the management of dental infections, most dentists prescribed penicillin (94.7%). Their foremost prescription choices for the presence of an anaerobic infection were metronidazole (48.5%) and penicillin (32%). For dental trauma, the most common antibiotic-prescribed cases were avulsion and contaminated wounds, followed by alveolar fracture. Antibiotics were prescribed as a first choice for dental infections and dental infections of anaerobic origin, with no significant differences between professional experience or dental specialty in the dentists (p > 0.05). Practitioners belonging to Ministry of Health dental centres significantly differed from all other groups in preferring the antibiotic cephalosporin for dental infections of anaerobic origin. Conclusions: Adherence to published guidelines for antibiotic prescriptions for anaerobic dental infections and dental trauma was low. Clearer, more specific guidelines and increased post-graduate education could lead to a reduction in the negative consequences of this issue’s resultant over-prescribed antibiotics.


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