Investigation of ballistic performance on 3D compound structure fabric by finite element analysis

Ballistic performance and moldability are two important properties for 3D curved-surface ballistic applications. However, these two properties are contradictory to each other and impossible to improve at the same time, which is a technical issue that needs to be solved urgently in the research for ballistic materials for 3D curved-surface ballistic applications. In order to solve this issue, a new 3D compound structure fabric has been developed as part of our former research and has been shown to provide better ballistic performance with equivalent moldability compared to 3D angle-interlock fabric—a well-known 3D material for 3D curved-surface ballistic applications. Nevertheless, the ballistic performance of this new fabric itself is not clear, and further research is necessary. In this study, the ballistic performance of this new 3D compound structure fabric was investigated via the finite element analysis (FEA) model to examine energy absorption and penetration resistance. A ballistic test was also carried out to verify the results of the FEA model, and this demonstrated that the theoretical model was consistent with the experimental results.

Structure Prediction and Mechanical Properties of Silicon Hexaboride on Ab Initio Level

Silicon borides represent very appealing industrial materials for research owing to their remarkable features, and, together with other boride and carbide-based materials, have very wide applications. Various Si–B phases have been investigated in the past, however a limited number of studies have been done on the pristine SiB6 compound. Structure prediction using a data mining ab initio approach has been performed in pure silicon hexaboride. Several novel structures, for which there are no previous experimental or theoretical data, have been discovered. Each of the structure candidates were locally optimized on the DFT level, employing the LDA-PZ and the GGA-PBE functional. Mechanical and elastic properties for each of the predicted and experimentally observed modifications have been investigated in great detail. In particular, the ductility/brittleness relationship, the character of the bonding, Young’s modulus E, bulk modulus B, and shear modulus K, including anisotropy, have been calculated and analyzed.

Experimental investigation of thermal performance in a rectangular channel using compound structure

An experimental study was conducted to measure the heat transfer and pressure drop in a rectangular channel emphasizing a compound structure to improve the cooling performance of gas turbine blades. W shaped, semicircular, and multi semicircular shaped ribs with dimples are studied and applied to a lower surface of a channel. The experiment was carried out at a Reynolds number ranging from 10,000 to 32,000 and the ratio of pitch (P) to height (e) of the rib was 10. Also, the ratio of rib height (e) to channel hydraulic diameter (Dh) was 0.187 and the dimple depth (δ) to dimple diameter (D) ratio was 0.2. It was observed that the combination of ribs and dimple channel (compound channel) has an average of 23 % more heat transfer than the ribbed channel. W rib compound channel shows the highest thermal performance and enhanced up to 30 % more heat transfer than semi and multi-semicircular compound channel. friction rise was observed in the compound channel compared to the ribbed channel.

CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Potentiation

Differentially screening the Fr-PPIChem chemical library on the BET BRD4-BDII versus -BDI bromodomains led to the discovery of a BDII selective tetrahydropyridothienopyrimidinone (THPTP)-based compound. Structure-activity relationship (SAR) and hit-to-lead approaches allowed us to develop CRCM5484, a highly potent inhibitor of BET proteins with a preferential and 475-fold selectivity for the second bromodomain of the BRD3 protein (BRD3-BDII) over its first bromodomain (BRD3-BDI). Its very low activity was demonstrated in various cell-based assays, corresponding with recent data describing other selective BDII compounds. However, screening on a drug sensitivity and resistance-profiling platform revealed its ability to potentiate the antileukemic activity in combination with various FDA-approved and/or in-development drugs in a cell- and context-dependent differential manner. Altogether, the results confirm the originality of the THPTP molecular mode of action in the BD cavity and its potential as chemical platform for the development of potent and selective bromodomain inhibitors.

Research on double-faced jacquard fabric with compound full-backed structure of three wefts

Weft-backed structures with compound weft colours can express the mixed colour effect. However, this structure is not suitable for jacquard fabrics with a double-faced shading effect in the traditional single layer design mode. Taking twenty-thread sateen with a step number (S) of 7 as an example, this paper investigates a design method for compound full-backed structure with three shaded-weave databases (SWDs) by selecting the primary weaves (PWs), designing the compound full-backed technical points and establishing the compound structure database with three SWDs. With this design method, a double-faced shading effect in combination with non-backed and full-backed effects on different sides of the jacquard fabric at the same position is generated. The fabric colour card was produced with three SWDs and three sets of different coloured wefts, and their colour values were measured, followed by an analysis of the compound structures on the reverse side, lightness, colour purity and colour difference (DE*ab) of the specimens. The results showed that the three covering effects on the reverse side, partly covered, critical position and totally covered, could be adjusted by controlling the step number and the transition direction of PW-C. For the specimens on the edges of the fabric colour card, their lightness and colour purity values showed a uniform transition effect along with the shading process; their colour differences ranged from 1.23 to 3.69, both in the range of 2–5, and showed a trace or slight colour difference between two adjacent fabric specimens, indicating that the colour shading effect with the three SWDs is stable.

Numerical Prediction of the Seismic Behavior of Reassembled Columns in Ancient Structures: An Anastylosis Model for the Temple of Apollo Pythios in Gortyn (Crete)

The Temple of Apollo Pythios in Gortyn (Crete, Greece) dates back to the mid-7th century BC. The temple underwent several transformations and an ultimate destruction over time that resulted in the current remains of a Roman colonnade composed of six fragmented stone columns lying on the ground within the naos. In addition, the region was struck by several earthquakes which contributed to the various changes. The analysis of the fragments composing the column portions and their geometric features provided a possible outline for their standing repositioning. Based on the current seismic hazard of the region, a predictive numerical model of the colonnade in the anastylosis conditions suggested the need for proper connections between the fragments and the bases to ensure their overall conservation as a compound structure. The comparison of various configurations of intervention and the simple superimposition of the fragments also provided details on the accomplishment of minimal and compatible solutions.

Oxidation state variation in bis-calix[4]arene supported decametallic Mn clusters

The reaction of MnCl2·4H2O, H8L (2,2’-bis-p-tBu-calix[4]arene) and NEt3 in a dmf/MeOH solvent mixture results in the formation of a mixed valent decametallic cluster of formula [MnII6MnIII4(L)2(µ3-OH)4(µ-OH)4(MeOH)4(dmf)4(MeCN)2]·MeCN (3). Complex 3 crystallises in the monoclinic space group P21/n with the asymmetric unit comprising half of the compound. Structure solution reveals that the bis-calix[4]arene ligands are arranged such that one TBC[4] moiety in each has undergone inversion in order to accommodate a [MnIII4MnII6] metallic skeleton that describes three vertex-sharing [MnIII2MnII2] butterflies. The structure is closely related to the species [MnIII6MnII4(L)2(μ3-O)2(μ3-OH)2(μ-OMe)4(H2O)4(dmf)8]·4dmf (4), the major difference being the oxidation level of the Mn ions in the core of the compound. DFT calculations on the full structures reveal that replacing the MnIII ions in 4 for MnII ions in 3 results in a significant decrease in the magnitude of some antiferromagnetic exchange contributions, a switch from ferromagnetic to antiferromagnetic in others, and the loss of significant spin frustration.

Applying Four-Steps Characteristic Ion Filtering with HPLC-QE Orbitrap MS Approach to Rapid Characterize Compound Structure s and Determine Major Representative Components in Modified Tabusen-2 Decoction

Background: Modified Tabusen-2 decoction (MTBD) is Traditional Chinese Mongolia Medicine, it is consist of “Lancitou” “Duzhong” “Sanqi” and “Honghua”. MTBD is mainly used to treat osteoporosis. However, the precise material basis of this prescription is not yet fully elucidated, which affects its modernization developmentMethods: We establish a new HPLC-QE Orbitrap MS technology with four-steps characteristic ion filtering (FSCIF) strategy to quickly and effectively identify the structural features of MTBD, and determine the representative compounds content. Then the quantitative method of nineteen main components in MTBD were built, and eight batches MTBD were determined as well. Results: By using the FSCIF strategy, a total of 143 compounds were unambiguously or tentatively identified, including 5 compounds were first reported in MTBD. Nineteen representative components were simultaneously quantified by HPLC-QE Orbitrap MS, and it is suitable for eight batches of MTBD. Methodology analysis showed that the assay method of 19 compounds (including three pairs of isomers) with a good repeatability, accuracy, and stability. Conclusion: The method established above was successfully applied to assess the quality of MTBD extracts, which prove that the concentrations of 19 compounds varied significantly in different batches of MTBD extracts. Collectively, our findings enhance our molecular understanding of the MTBD formulation and will allow us to control its quality in a better way. At the same time, this study can promote the development and utilization of ethnic medicine.