The Relationship Between Financial Literation Towards Users Of Loan Transacted Applications In The Millennial Generation

This study aimed to find a relationship between financial literacy and the use of loans transacted for the millennial generation—qualitative approach research method. The population in this study is the millennial generation in Bandung who have made loans transacted. The sample used was 270 people with a non-probability sampling technique with the criteria of users of online loan fintech products. The analysis technique used is a simple correlation and regression test. The results obtained show a significant influence between financial literacy variables on loans transacted with a t-value of 6,947. While the results of the correlation test state that the contribution of financial literacy to loans transacted has a contribution of 0.567, meaning that there is a fairly close relationship in terms of positive linear correlation value (r = 1), which means that every increase in financial literacy can increase the level of loans transacted. Keywords—; Fintech; Financial Literacy; Loans transacted Applications;Millenial

Collinearity of alpha-helices or beta strands in membrane proteins causes a characteristic peak centred on 4.9 Å resolution in diffraction intensity profiles, inducing higher diffraction anisotropy

Diffraction anisotropy is a phenomenon that impacts more specifically membrane proteins, compared to soluble ones, but the reasons for this discrepancy remained unclear. Often, it is referred to a difference in resolution limits between highest and lowest diffraction limits as a signature for anisotropy. We show in this article that there is no simple correlation between anisotropy and difference in resolution limits, with notably a substantial number of structures displaying various anisotropy with no difference in resolution limits. We further investigated diffraction intensity profiles, and observed a peak centred on 4.9Å resolution more predominant in membrane proteins. Since this peak is in the region corresponding to secondary structures, we investigated the influence of secondary structure ratio. We showed that secondary structure content has little influence on this profile, while secondary structure collinearity in membrane proteins correlate with a stronger peak. Finally, we could further show that the presence of this peak is linked to higher diffraction anisotropy.SynopsisMembrane protein diffraction anisotropy originates from a peak at 4.9 Å resolution in intensity profiles, due to secondary structure collinearity.

Autism spectrum disorders and atopic dermatitis: a new perspective from country-based prevalence data

Recently, a continuous growth for both neurodevelopmental and atopic diseases’ incidence was seen throughout the world. Notably, autism spectrum disorders (ASD) and atopic dermatitis (AD) attracted the attention of clinicians and scientists for their impact on the quality of life of patients, starting during childhood. Despite a number of hypotheses about common pathogenesis between the two disorders, uncertainty is still present, and data coming from various parts of the world are contradictory. Fortunately, works recently published have brought useful material for comparative analysis to the benefit of the scientific community, making large scale, country-based perspectives methodologically viable. In light of that, the present study took into account uniform data, available from country-based registries or related publications, dealing with the prevalence of the two conditions around the world, and tried to setup a simple correlation analysis between the two. According to such data, the growth of AD and ASD prevalence appear uncorrelated, leading to hypothesise that, if a common etiopathological pathway exists between the two conditions, they are likely to interact to each other due to a complex interplay of co-morbidities, genes and environmental players not enough explained by a simple correlation analysis. Such facts are worth investigation in future research.

Pedestrian Deaths During the COVID-19 Pandemic

The COVID pandemic provides a natural experiment examining how a 50–60% reduction in pedestrian activity might lead to a reduction in pedestrian deaths. We assessed whether the reduction in pedestrian deaths was proportional to a one-to-one matching presumed in statistics correlating mobility with fatality. The primary analysis examined New York (largest city in US), and the validation analysis examined Toronto (largest city in Canada). We identified pedestrian activity in each location from the Apple Mobility database, normalized to the baseline in January 2020. We calculated monthly pedestrian deaths from the Vision Zero database in each city with baseline data from 3 prior years. We found a large initial reduction in pedestrian deaths during the lockdown in New York that was transient and not statistically significant during the summer and autumn despite sustained reductions in pedestrian activity. Similarly, we found a large initial reduction in pedestrian deaths during the lockdown in Toronto that was transient and not sustained. Together, these data suggest the substantial reductions in pedestrian activity during the COVID pandemic have no simple correlation with pedestrian fatality counts in the same locations. An awareness of this finding emphasizes the role of unmeasured modifiable individual factors beyond pedestrian infrastructure or other structural contributors.

Effect of Temperature on the Incidence of Cerebro-Spinal Meningitis and Its Management in Funtua Local Government Area, Katsina State, Nigeria

This study was aimed at analysing the effect of temperature on the incidence of cerebro-spinal meningitis and its management in Funtua General Hospital of Katsina State, Nigeria from 1986-2015. For each year, monthly and annual incidence of CSM occurrence in the study area for the 30 years period was subjected to time series analysis. Linear trend line equation was fitted in order to determine the direction of change in the incidence of CSM. The relationship between temperature and the incidence of meningitis was analysed using simple correlation. To determine the management method of CSM in the area, a questionnaire was used to generate information from sampled respondents and analysed using descriptive statistics. The monthly distribution of CSM cases (1986-2015) indicated April and March had the highest incidence cases (1606 and 1128 respectively) while the lowest cases were recorded in September and October with (1 case) each. The seasonal variation also showed that the highest incidence cases fell within the hot-dry season which mark the period with the highest average temperatures while the lowest incidence cases fell within the hot-wet season when humidity is high in the area. Annual trend of CSM indicated an increasing trend (approximately 60 persons) over the 30year period in the study area. There is a significant and positive relationship between mean monthly temperature and incidence of meningitis with an observed value of (p < 0.05 and r = 0.592). The observed correlation (r = -0.141, p>0.05) indicated that there was negative and insignificant relationship between annual temperature and the incidence of meningitis in the study area. In conclusion, meningitis in the study area over the 30years under review has been a recurrent epidemic however; the rate of occurrence differs from year to year. Majority (78%) used the orthodox method to manage CSM while 22% used the traditional method who claimed it was effective as they recovered from the disease.

Evaluation of Serviceability of Canal Lining Based on AHP–Simple Correlation Function Method–Cloud Model: A Case Study in Henan Province, China

In the process of sustainable development within modern agriculture, in order to ensure that agricultural production has adequate water resources, canal lining (CL) is often used to transport water in order to reduce water seepage, thus promoting the sustainable utilization of water resources. However, due to the influence of the terrain, environment, human factors and other factors, the CL often suffers a certain degree of damage. Therefore, it is necessary to evaluate the serviceability of the CL, so to realize the sustainable use of the CL strategy. Aiming at the weight assignment of CL evaluation indices that are subjective and not combined with actual index data, a weight calculation method based on the Analytic Hierarchy Process (AHP)–simple correlation function (SCF) method was proposed, and game theory was used to achieve combination weighting. For the evaluation indices with the characteristics of fuzziness and randomness, the cloud model (CM) was used to comprehensively consider these characteristics in order to realize the evaluation. Finally, a method to measure serviceability of CL based on AHP–SCF–CM was proposed. Taking a CL project in China as an example, this method was used to evaluate the serviceability of the CL. The evaluation result showed that the serviceability of the CL was poor, and the qualitative evaluation result was consistent with the actual damage condition of the project; meanwhile, a comparative study was performed in combination with the AHP–Entropy Weight (EW)–unascertained measurement theory (UMT). The quantitative evaluation results of the two methods displayed the same grade of serviceability, which verifies that the method proposed in this paper is more reasonable, objective and feasible from both qualitative and quantitative perspectives. Furthermore, the evaluation results lay the foundation for subsequent maintenance and fault prevention of the canal.

Is 18F-FDG PET/CT Beneficial for Newly Diagnosed Breast Cancer Patients With Low Proportion of ER Expression?

ObjectiveIt is unclear whether the receptor status of breast malignancy or the proportion of receptors expression is useful in the interpretation of 18F-FDG PET/CT. This study’s purpose was to analyze whether 18F-FDG PET/CT was valuable for helping newly diagnosed breast cancer patients find suspected or unsuspected metastasis lesions based on the proportion of receptors expression.Materials and MethodsEighty newly diagnosed breast cancer patients were divided into six groups, containing N0 (no extraaxillary lymph node metastasis), N1 (extraaxillary lymph node metastasis), M0 (no distant metastasis), and M1 (distant metastasis) groups, C0 (no unsuspected metastasis), and C1 (unsuspected metastasis and treatment plan changed) detected by PET/CT. The main data, including the proportion of receptors ER (estrogen receptor), PR (progesterone receptor), and Her-2 (human epidermal growth factor receptor 2) status, were extracted. Simple correlation and logistic regression were preformed to analyze the association between them.ResultsPatients in N1 group had lower proportion of ER (%) and PR (%) than that in N0 group (ER: 2 [0–80] vs. 80 [15–95]; PR: 1 [0–10] vs. 20 [0–45], p&lt;0.001). Moreover, the proportions of ER and PR were negatively correlated with N1 (ER: [r= −0.339, p= 0.002], PR: [r= −0.247, p= 0.011]) by simple correlation. Also, patients in C1 group had lower proportion of ER (%) and PR (%) than those in C0 group (ER: 10 [0–85] vs. 80 [15–90], p=0.026; PR: 1 [0–10] vs. 20 [0–70], p=0.041), while the distribution of ER and PR between M1 and M0 group had no significant difference. After the adjustment of traditional factors, the negative correlation between the proportion of ER (OR=0.986, 95% CI of OR [0.972–0.999], p=0.016) and C1 was found by logistic regression, cutoff value was 25% (ER) calculated by ROC (Receiver Operating Characteristic) curve (AUC [Area Under Curve]= 0.647, p=0.024).ConclusionThe proportion of ER in newly diagnosed breast cancer was negatively correlated with unsuspected metastasis detected by 18F-FDG PET/CT. 18F-FDG PET/CT might be recommended for newly diagnosed breast cancer patients with single lesions when the ER expression proportion is less than 25% to find unsuspected metastasis lesions and to modify treatment plan contrasted with conventional imaging and clinical examination.

Antecedents and Outcomes of Corporate Reputation Customer-based Analysis

For any organization its image and reputation is the level of affectionateness in the minds of employees, customers, expected candidates, and competitors, Reputation is the most critical and strategic asset that a corporation possess (Cravens et al., 2003). The objectives of the study was to examine the antecedents and outcomes of corporate reputation. The study was quantitative in nature. Data were collected by using convenient sampling technique from twin cities (i.e. Islamabad and Rawalpindi) of Pakistan. Respondents were asked to answer the questions keeping in mind the mobile company whose connection they use frequently or on permanent basis. Simple correlation and regression methods were used for analysis of data. Results revealed that if a customer is satisfied with the products and services offered by the company than the reputation of the company in the eyes of the customer will increase. In the same way, when customer has trust on the services offered by the company his confidence level will increase on the future offers and service quality of company resulting an increase in the reputation of the firm and this company reputation will influence customer loyalty and positive word of mouth. Managerial implications and recommendations for future research are given at the end.

The correlation of variable affecting yield on anthocyanins corn

Variable importance under vegetative and generative stage for effecting of grain yield opv anthocyanins corn. Simple correlation and regression analysis has been conducted between grain yield as dependent variable (yi) with all independent variable (xi, i: 1,2,3,…,6) as vegetative and generative stage. Stepwise of multiple regression was be used for define of variable was more important to affecting of yield.The experiment were conducted in Maros and Bajeng experimental farm on rainy 2017, data has been collected as sample from 30 plants per se. Two blocks of experiment 17x25m were planting of with spacing 75x20 cm one plant per hole, length of plot 15 m. Fertilizer be applied with Urea-Ponska (300-200) kg/ha. Anthocyanin’s corn held to increase of human health. The origin of anthocyanins corn is from Mesoamerica it is a pigment that give color of purple to black may affect to anticipated of viral (virus), cholesterol, heart disease, obesity, and cancerThe result multiple regression shown that variable which is be increase of yield and significant different founded in Maros were plant height (x1), water content of seeds (x2), and ear height. (x5). Model: y:3.404+0.027x1+0.018x2-0.073x5, R2:0.645. In Bajeng shown that water content of seeds (x5), number of seeds per cob (x7), and 1000 seeds (x8), Model was yi=4.096-1.776x5+0.087x7+0.023x8; R2:0.92. In The two-location yield, be decrease if water content of seed was increase.

Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes

Integrating single-cell transcriptomes and epigenomes across diverse cell types can link genes with the cis-regulatory elements (CREs) that control expression. Gene co-expression across cell types confounds simple correlation-based analysis and results in high false prediction rates. We developed a procedure that controls for co-expression between genes and integrates multiple molecular modalities, and used it to identify >10,000 gene-CRE pairs that contribute to gene expression programs in different cell types in the mouse brain.