scale characterization
Recently Published Documents


TOTAL DOCUMENTS

666
(FIVE YEARS 195)

H-INDEX

46
(FIVE YEARS 10)

2022 ◽  
Vol 8 (2) ◽  
Author(s):  
Paula A. Gago ◽  
Stefan Boettcher

The grain-scale dynamics of the internal energy inside a tapped granular pile is studied, advancing on a kinetic theory of grains.


2022 ◽  
Vol 16 (1) ◽  
pp. e0010084
Author(s):  
Wei-Liang Liu ◽  
Hui-Ying Yu ◽  
Yu-Xuan Chen ◽  
Bo-Yu Chen ◽  
Shiang Ning Leaw ◽  
...  

Dengue fever is one of the most severe viral diseases transmitted by Aedes mosquitoes, with traditional approaches of disease control proving insufficient to prevent significant disease burden. Release of Wolbachia-transinfected mosquitoes offers a promising alternative control methodologies; Wolbachia-transinfected female Aedes aegypti demonstrate reduced dengue virus transmission, whilst Wolbachia-transinfected males cause zygotic lethality when crossed with uninfected females, providing a method for suppressing mosquito populations. Although highly promising, the delicate nature of population control strategies and differences between local species populations means that controlled releases of Wolbachia-transinfected mosquitoes cannot be performed without extensive testing on specific local Ae. aegypti populations. In order to investigate the potential for using Wolbachia to suppress local Ae. aegypti populations in Taiwan, we performed lab-based and semi-field fitness trials. We first transinfected the Wolbachia strain wAlbB into a local Ae. aegypti population (wAlbB-Tw) and found no significant changes in lifespan, fecundity and fertility when compared to controls. In the laboratory, we found that as the proportion of released male mosquitoes carrying Wolbachia was increased, population suppression could reach up to 100%. Equivalent experiments in semi-field experiments found suppression rates of up to 70%. The release of different ratios of wAlbB-Tw males in the semi-field system provided an estimate of the optimal size of male releases. Our results indicate that wAlbB-Tw has significant potential for use in vector control strategies aimed at Ae. aegypti population suppression in Taiwan. Open field release trials are now necessary to confirm that wAlbB-Tw mediated suppression is feasible in natural environments.


2022 ◽  
Author(s):  
Hao Li ◽  
Changhyeon Yoo ◽  
Tae-Jun Ko ◽  
Jung Han Kim ◽  
Yeonwoong Jung

The heterogeneity features among 2-dimensional (2D) transition metal dichalcogenides (TMDs) layered materials endow them with distinctive properties for a vast array of novel applications. Their unique properties stem from the...


Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2801
Author(s):  
Eva Gato ◽  
Astrid Perez ◽  
Alicja Rosalowska ◽  
Maria Celeiro ◽  
German Bou ◽  
...  

An extraction method was designed and scaled up to produce multicomponent polyphenolic extracts from blueberries (Vaccinium corymbosum) of three different varieties. The process was specifically drawn up to comply with green chemistry principles. Extracts were obtained for the direct assessment of their antimicrobial and antiadhesive activities, and their direct use in the control of infections caused by concerning multidrug-resistant nosocomial pathogens. Analytical characterization was performed by liquid chromatography–tandem mass spectrometry (LC–MS/MS). Similar qualitative profiles were obtained in the three studied varieties with some significant quantitative differences. Up to 22 different polyphenols were identified with a clear predominance of anthocyani(di)ns followed by flavanols, non-flavonoids, and far behind by flavan-3-ols and procyanidins. The individual content of the main polyphenols was also discussed. A pilot scale extract has been also produced as a proof-of-concept, showing that scaling-up triples the content of bioactive phytochemicals. The effect of the polyphenolic extracts was analyzed against seven multidrug-resistance bacterial species by performing biofilm formation and growth and killing curves assays. All the studied varieties showed antibacterial and antiadhesive activities, being the extract containing the highest concentration of bioactive polyphenols, the most active with a high bactericidal effect.


Sign in / Sign up

Export Citation Format

Share Document