artificial system
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PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0261771
Author(s):  
Dan Zhu ◽  
Yaoyao Wei ◽  
Hainan Huang ◽  
Tian Xie

The outbreak of unconventional emergencies leads to a surge in demand for emergency supplies. How to effectively arrange emergency production processes and improve production efficiency is significant. The emergency manufacturing systems are typically complex systems, which are difficult to be analyzed by using physical experiments. Based on the theory of Random Service System (RSS) and Parallel Emergency Management System (PeMS), a parallel simulation and optimization framework of production processes for surging demand of emergency supplies is constructed. Under this novel framework, an artificial system model paralleling with the real scenarios is established and optimized by the parallel implementation processes. Furthermore, a concrete example of mask shortage, which occurred at Huoshenshan Hospital in the COVID-19 pandemic, verifies the feasibility of this method.


2021 ◽  
Author(s):  
Stefano Corrà ◽  
Marina Tranfik Bakic ◽  
Jessica Groppi ◽  
Massimo Baroncini ◽  
Serena Silvi ◽  
...  

Natural and artificial autonomous molecular machines operate by constantly dissipating energy coming from an external source to maintain a non-equilibrium state. The in-depth study of these dissipative states is highly challenging as they exist only as long as energy is provided. Here we report on the detailed physicochemical characterization of the dissipative operation of a supramolecular pump transducing light energy into chemical energy by shifting the equilibrium of self-assembly reactions. The composition of the system under light irradiation was followed in real-time by 1H NMR and parameters such as the dissipation and the energy storage at the steady state were extracted for four different irradiation intensities. For the first time in an artificial system, we quantitatively probed the relationship between the light energy input and the deviation of the dissipative state from thermodynamic equilibrium. Our results also provide a testing ground for newly developed theoretical models.


2021 ◽  
Vol 9 ◽  
Author(s):  
D. Osuna Ruiz ◽  
O. Alejos ◽  
V. Raposo ◽  
E. Martínez

Current driven domain wall motion in curved Heavy Metal/Ferrimagnetic/Oxide multilayer strips is investigated using systematic micromagnetic simulations which account for spin-orbit coupling phenomena. Domain wall velocity and characteristic relaxation times are studied as functions of the geometry, curvature and width of the strip, at and out of the angular momentum compensation. Results show that domain walls can propagate faster and without a significant distortion in such strips in contrast to their ferromagnetic counterparts. Using an artificial system based on a straight strip with an equivalent current density distribution, we can discern its influence on the wall terminal velocity, as part of a more general geometrical influence due to the curved shape. Curved and narrow ferrimagnetic strips are promising candidates for designing high speed and fast response spintronic circuitry based on current-driven domain wall motion.


Author(s):  
Ryugo TERO ◽  
Natsumi Kobayashi

Abstract Supported lipid bilayers (SLBs) are artificial lipid bilayers at solid-liquid interfaces applied as cell membrane model systems. An advantage of the artificial system is that the lipid composition can be controlled arbitrarily. On the other hand, the SLB formation process and its efficiency are affected by the properties of the solid substrate surface. In this study, we investigated the effect of the electrostatic interaction between the negatively charged SiO2/Si substrate surface and the lipid bilayer membrane on the composition of binary SLBs comprising anionic and neutral lipids. The phase transition temperature and the area fraction of lipid domains of SLB were evaluated by fluorescence microscopy and the fluorescence recovery after photobleaching. The neutral lipid was preferably included in SLB, but the anionic lipid ratio increased with Ca2+ concentration during the SLB formation. The lipid composition in SLB can be controlled by modulating the substrate-induced electrostatic potential.


Insects ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1046
Author(s):  
Hua Wu ◽  
Li Cao ◽  
Meiyu He ◽  
Richou Han ◽  
Patrick De Clercq

The Chinese cordyceps, a parasitic Ophiocordyceps sinensis fungus–Thitarodes/Hepialus larva complex, is a valuable biological resource endemic to the Tibetan Plateau. Protection of the Plateau environment and huge market demand make it necessary to culture this complex in an artificial system. A method for the large-scale artificial rearing of the Thitarodes/Hepialus insect host has been established. However, the deterioration of the insect rearing population and low mummification of the infected larvae by the fungus constrain effective commercial cultivation. Hybridization of Thitarodes/Hepialus populations may be needed to overcome this problem. The species T. shambalaensis (GG♂ × GG♀) and an undescribed Thitarodes species (SD♂ × SD♀) were inbred or hybridized to evaluate the biological parameters, larval sensitivity to the fungal infection and mitochondrial genomes of the resulting populations. The two parental Thitarodes species exhibited significant differences in adult fresh weights and body lengths but not in pupal emergence rates. Hybridization of T. shambalaensis and Thitarodes sp. allowed producing a new generation. The SD♂ × GG♀ population showed a higher population trend index than the SD♂ × SD♀ population, implying increased population growth compared with the male parent. The sensitivity of the inbred larval populations to four fungal isolates of O. sinensis also differed. This provides possibilities to create Thitarodes/Hepialus populations with increased growth potential for the improved artificial production of the insect hosts. The mitochondrial genomes of GG♂ × GG♀, SD♂ × SD♀ and SD♂ × GG♀ were 15,612 bp, 15,389 bp and 15,496 bp in length, with an A + T content of 80.92%, 82.35% and 80.87%, respectively. The A + T-rich region contains 787 bp with two 114 bp repetitive sequences, 554 bp without repetitive sequences and 673 bp without repetitive sequences in GG♂ × GG♀, SD♂ × SD♀ and SD♂ × GG♀, respectively. The hybrid population (SD♂ × GG♀) was located in the same clade with GG♂ × GG♀, based on the phylogenetic tree constructed by 13 PCGs, implying the maternal inheritance of mitochondrial DNA.


Author(s):  
Bob Sturm ◽  
Hugo Maruri-Aguilar

The Ai Music Generation Challenge 2020 had three objectives: 1) to promote meaningful approaches to evaluating artificial intelligence (Ai) applied to music;2) to see how music Ai research can benefit from considering traditional music, and how traditional music might benefit from music Ai research; and 3)to facilitate discussions about the ethics of music Ai research applied to traditional music practices.There were six participants and a benchmark in the challenge, each competing to build an artificial system that generates the most plausible double jigs, as judged against the 365 published in solved'', but that the evaluation of such systems can be done in meaningful ways.The article ends by reflecting on the challenge and considering the coming 2021 challenge.


2021 ◽  
Author(s):  
Tomoya Kojima ◽  
Hiroyuki Kitahata ◽  
Kouichi Asakura ◽  
Taisuke Banno

Collective motion is ubiquitous in living systems. Although various biomimetic artificial systems have been constructed, there have been few studies reported on collective motion induced by the coupling of chemical reactions, diffusion and convection in a far-from-equilibrium state. In this study, we report an artificial system of oil droplets in a surfactant solution wherein the collective motion of multiple droplets and pattern formation occurred concurrently. Using photo-responsive surfactants with an azobenzene moiety, the assembly of droplets and the formation of circular patterns around the formed droplet clusters occurred under UV illumination, whereas the disassembly of droplets and disappearance of the patterns occurred under subsequent visible light illumination. The observed dynamics were induced by Marangoni flows based on the reversible photoisomerisation of azobenzene-containing surfactants. The phenomena were considered analogous to the bioconvection of microorganisms. These findings could be useful for understanding the mechanism of motion of life in terms of physicochemical aspects.


2021 ◽  
Vol 11 (15) ◽  
pp. 6950
Author(s):  
Mauricio Marcano ◽  
Fabio Tango ◽  
Joseba Sarabia ◽  
Andrea Castellano ◽  
Joshué Pérez ◽  
...  

The “classical” SAE LoA for automated driving can present several drawbacks, and the SAE-L2 and SAE-L3, in particular, can lead to the so-called “irony of automation”, where the driver is substituted by the artificial system, but is still regarded as a “supervisor” or as a “fallback mechanism”. To overcome this problem, while taking advantage of the latest technology, we regard both human and machine as members of a unique team that share the driving task. Depending on the available resources (in terms of driver’s status, system state, and environment conditions) and considering that they are very dynamic, an adaptive assignment of authority for each member of the team is needed. This is achieved by designing a technology enabler, constituted by the intelligent and adaptive co-pilot. It comprises (1) a lateral shared controller based on NMPC, which applies the authority, (2) an arbitration module based on FIS, which calculates the authority, and (3) a visual HMI, as an enabler of trust in automation decisions and actions. The benefits of such a system are shown in this paper through a comparison of the shared control driving mode, with manual driving (as a baseline) and lane-keeping and lane-centering (as two commercial ADAS). Tests are performed in a use case where support for a distracted driver is given. Quantitative and qualitative results confirm the hypothesis that shared control offers the best balance between performance, safety, and comfort during the driving task.


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