In this paper, the dynamic behaviors are studied for a stochastic delayed avian influenza model with mutation and temporary immunity. First, we prove the existence and uniqueness of the global positive solution for the stochastic model. Second, we give two different thresholds [Formula: see text] and [Formula: see text], and further establish the sufficient conditions of extinction and persistence in the mean for the avian-only subsystem and avian-human system, respectively. Compared with the corresponding deterministic model, the thresholds affected by the white noises are smaller than the ones of the deterministic system. Finally, numerical simulations are carried out to support our theoretical results. It is concluded that the vaccination immunity period can suppress the spread of avian influenza during poultry and human populations, while prompt the spread of mutant avian influenza in human population.