william osler
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2021 ◽  
Vol 9 (1) ◽  
pp. 214
Author(s):  
Obed Manuel Kuruvilla ◽  
Arun Narayanapanicker ◽  
Anu Tresa Antony

Mycotic aneurysm of popliteal artery is a very rare condition, most commonly caused by gram positive organisms. This term was coined by William Osler describing aneurysms associated with bacterial endocarditis. Though cases of peripheral vessel mycotic aneurysm are very rare, it is a dangerous condition as it can go for rupture/ thrombosis. The treatment of choice is resection and revascularization, preferably by using autologous vein graft along with antibiotics. A 35-year-old female who presented with features of cerebrovascular accident, during the course of stay was diagnosed to have mycotic aneurysm of the left popliteal artery. We describe the clinical course, investigation findings and challenges faced in management of the case.


2021 ◽  
pp. 096777202110526
Author(s):  
Graham Kyle ◽  
Charles S Bryan

On 23 September 1919, Sir William Osler, after a telephone call from his friend Dyson Perrins, went to Glasgow where he saw a 40-year-old woman, Bethia Fulton Martin, in consultation with three local physicians. Osler called it “one of those remarkable Erythema cases (all sorts of skin lesions and three months on and off consolidation of both lower lobes).” Mrs Martin died 114 days later; her death certificate listed “angioneurotic oedema with chronic nephritis” and “tuberculous enlargement of the mediastinal lymph nodes.” Osler died 18 days before Mrs Martin of complications from a respiratory infection acquired on his way home from Scotland. We discuss factors that possibly prompted Osler to go to Scotland, including his role with the newly formed University Grants Committee, and the differential diagnosis of the case, which is mainly between systemic lupus erythematosus and Henoch-Schönlein purpura.


2021 ◽  
Author(s):  
Karem Lisseth Aguirre Realpe ◽  
Josselin Estefania Villamarin Barreiro ◽  
Eduardo Estefano Camacho Sig-Tú ◽  
Aguirre Espinosa Andrea Estefania ◽  
Blanca Andreina Mendoza Lino ◽  
...  
Keyword(s):  

La Medicina Interna se basa en una atención integral a todas las enfermedades que tienen relación con los pacientes desde los 15 años de edad, tanto en forma ambulatoria, como con hospitalización, excluyendo las que necesiten atención quirúrgica, psiquiátrica o gineco-obstétrica. También incluyen controles en personas sanas dirigidas a la prevención y detección precoz de enfermedades y la promoción de la salud, inmunizaciones (vacunas) y chequeos de salud, entre otros. William Osler, quien es considerado el padre de la Medicina Interna, fue admirado por su capacidad de trabajo, visión clínica de los problemas del enfermo y desarrollo de actividades alrededor del paciente. Él abrió paso a la especialidad en la primera mitad del siglo XX en donde el internista fue reconocido no solo por brindar una atención longitudinal a los pacientes con enfermedades complejas, sino que al mismo tiempo era el consultante de médicos generales debido a su capacidad diagnóstica, convirtiéndose así en el eje fundamental de los hospitales y los servicios ambulatorios de su época. En este libro, Medicina Interna, se actualizan temas de gran importancia para el ejercicio de la profesión. Esta obra puesta hoy a la disposición y consideración de nuestros profesionales, será sin dudas un instrumento de apoyo imprescindible para el trabajo diario y una herramienta de consulta siempre a mano, donde quiera que se encuentren en la práctica de su profesión, incluso en los lugares más recónditos, en el ejercicio de la prevención y atención de la salud del hombre.


2021 ◽  
Vol 70 (2) ◽  
pp. 195-203
Author(s):  
Simona Giardina ◽  
Pietro Refolo ◽  
Antonio G. Spagnolo

Facendo proprie le riflessioni della scrittrice iraniana Azar Nafisi (“La Repubblica dell’immaginazione”, 2015), secondo la quale la conoscenza immaginativa   pragmatica e ispirandosi al grande medico William Osler (1849- 1919), bibliofilo appassionato, che stil  una lista di testi classici che ogni futuro medico avrebbe dovuto leggere – la c.d. bedside library –, gli Autori sottolineano l’importanza dei libri classici per la crescita personale dei medici e per la loro competenza clinica. Anche Italo Calvino affermava che ci sono cose che solo la letteratura pu  dare con i suoi mezzi specifici (Lezioni americane, 1988). La grande letteratura   un ponte che consente il dialogo a prescindere dai reciproci mondi di appartenenza (universalit );   luogo dell’immedesimazione (empatia); porta alla luce gli archetipi del comportamento umano (risonanza etica). Su questi presupposti si basa l’idea di stimolare la lettura dei classici sin dal primo anno della formazione degli studenti di medicina nell’ambito delle Medical Humanities.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jeffrey C. Posnick
Keyword(s):  

2021 ◽  
pp. 096777202110189
Author(s):  
Kacper Niburski

Sir William Osler espoused a particularly idealized medical life that included the patient in the physician's worldview. Disease is not considered a monolith, only a reflection of one's broader health. Death, too, is configured as a part of one's being, not as a thing apart from life. The wholesomeness that characterized Osler's practice is well known—however, his long discussions and thoughts on death have not been sufficiently analyzed. His clinical views have been hinted at and numerous medical historians have noted that Osler's worldview on death was avant-garde for its time, one in which he described finality not as a time of suffering and anguish, but as “singularly free from mental distress.” This essay contends with this simple view. This straightforward understanding becomes complicated when delving into such primary resources as Osler's Study on Dying cards, his writings on other medical conditions, and personal reflections following the personal losses of his sons Edward Revere Osler and Paul Revere Osler. This essay contends that the loss and the death he imagines is not one of peace, but rather, of horror and terror. Furthermore, the primary sources show Osler not as the paragon of flawless clinical acumen and reasoning, but a man of personal beliefs that were in conflict with views he espoused more publicly. The essay therefore reconceptualizes the common understanding of a stoic Osler, determines how death prefigures into Oslerian thought, and challenges the idea of an Oslerian simple death.


2021 ◽  
Vol 88 (2) ◽  
pp. 226-228
Author(s):  
Tod Worner
Keyword(s):  

William Osler has been largely forgotten, but his abiding wisdom speaks loudly to a profession consumed in burnout & uncertainty.


2021 ◽  
pp. 1-6
Author(s):  
Richard Leblanc

Neurosurgery is predicated on the knowledge of the structure-function relationship of the brain. When the topic is broached in its historiography, it begins with Fritch and Hitzig's report on the localization of motor function in the cortex of the dog and skips rapidly to Wilder Penfield's homunculus. In that gap are found the origins of modern neurosurgery in 3 papers published by Jean-Martin Charcot and Albert Pitres between 1877 and 1879 in which they describe the somatotopic organization of the human motor cortex and draw the first human brain map. Their findings, obtained through the clinicopathological method, gave relevance to David Ferrier's observations in animals. Their work was extensively cited, and their illustrations reproduced by Ferrier in his landmark lecture to the Royal College of Physicians in 1878. It was known to William Macewen, who used localization to guide him in resecting intracranial mass lesions, and to William Osler and John Hughlings Jackson, who were early advocates of intracranial surgery. This paper describes Charcot and Pitres' discovery of the cortical origin of human voluntary movement and its somatotopic organization, and their influence on 19th-century intracranial surgery. It fills a gap in the historiography of cerebral localization and neurosurgery.


2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Manish Narang ◽  
Ramanpreet Walia ◽  
Upendra Kaul ◽  
Krishnakutty Sudhir

In the year 1892, Sir William Osler, the legendary Canadian physician and one of the four founding professors of Johns Hopkins Hospital, said “If it were not for the great variability among individuals, medicine might as well be a science and not an art”. It is this heterogeneity among patients with seemingly homogenous medical conditions, that form the basis of what we today refer to as precision medicine. The fundamental of precision medicine is based on the tenets of ‘The right drug for the right patient at the right time’. Personalized or precision medicine found immense popularity in oncology. With the completion of Human Genome Project and the advent of genomics, big data and artificial intelligence, 21st century saw rapid progress of precision medicine in predicting, diagnosing and treating cancer. However, the same has not happened to cardiovascular diseases, the biggest killer of humanity. In this review article, we aim to address the concepts, components, outcomes and applications of precision medicine in general, and to review the evolving paradigm of how precision medicine is shaping the management of cardiovascular diseases. We delve deep into the aspects of risk prediction, preventative measures, and targeted therapeutic approaches for cardiovascular diseases. We also look at the recent trends and current applications of precision medicine in this area, the problems they solve and the challenges they possess, and what is in store for the future. Finally, we review the application of artificial intelligence specific to cardiovascular diseases, and the role of precision medicine in interventional cardiology.


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