The aim of this work is to estimate the seismic reliability of a simple typical two span lifeline base-isolated bridge designed to behave essentially elastic or as per the Canadian Highway Bridge Design Code, for seven localities in Quebec. Two limit states are considered for possible failure due to unacceptable damage: by flexure at pier-base and by displacement within the SIS. Main problem random variables (RVs) considered and modeled are: Seismic hazard, temperature, pier base dimensions and material mechanical properties. The Monte-Carlo method is used to evaluate each limit state reliability and probability of failure. Preliminary results reveal that notwithstanding the large temperature and seismic hazard variabilities between the seven sites in Quebec, the global reliability indices are almost uniform, around 3.45±0.02. Furthermore, security factor (i.e.1.25) on SIS displacement capacity results in reliability indices for SIS displacement are not levelled with the flexural reliability indices and needs further exam and consideration.