liver atrophy
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2021 ◽  
Author(s):  
Junichiro Takahashi ◽  
Madoka Mori-Yoshimura ◽  
Hajime Ariga ◽  
Noriko Sato ◽  
Ichizo Nishino ◽  
...  

Abstract Purpose: Chilaiditi’s sign (CS), hepatodiaphragmatic interposition of the intestine, was caused by morphological abnormalities such as diaphragmatic atrophy, intestinal dilation, and liver atrophy. The sign is potentially important due to associations with clinically recurrent abdominal pain or even colonic volvulus. In general, neuromuscular disease (NMD) could have the high prevalence of CS because of widened hepatodiaphragmatic space, following diaphragmatic atrophy. Particularly, in late-onset Pompe disease (LOPD), glycogen accumulation in smooth muscle of intestine could lead to the abnormal dilation of intestine. Though the prevalence of CS in LOPD could be high because of developing two main factors of CS, no studies have evaluated the prevalence of CS in LOPD. Our aim was to investigate the prevalence of CS in LOPD, and to identify the risk factors of CS in LOPD patients. Methods: Medical records of genetically confirmed patients of Pompe disease at the National Center Hospital, National Center of Neurology and Psychiatry were retrospectively reviewed. We evaluated CS using chest X-ray (CXR) and abdominal CT and assessed the prevalence of CS in LOPD patients. We also divided the patients into two groups, CS and non-CS group, and evaluated the factor associated with CS compared to clinical variables between groups. Results: Three of seven (43%) were detected in CS. CS group (P5-7) and non-CS group (P1-4) were obtained. In comparison of clinical variables, the severity of atrophy in right diaphragms was significantly higher in CS than non-CS groups (p =0.029). Also, the frequency of abnormal position of right diaphragm and liver, and abnormally dilated bowel was seen in all of CS patients, but none of non-CS patient (p = 0.029, each). Conclusion: In LOPD patients, the prevalence of CS was much higher of 43%, compared to healthy groups, or even in similarly respiratory muscle impaired neuromuscular diseases such as Duchenne muscular dystrophy (DMD) or Myotonic dystrophy type 1 (DM1). The anatomically abnormal position of diaphragm and liver, atrophy and fat infiltration of diaphragms, and abnormally dilated bowel were significantly associated with CS in LOPD. Since CS can cause intestinal symptoms or even contribute to sudden-death of intestinal volvulus, we should pay more attention to CXR or abdominal CT as follow up in LOPD patients.


2021 ◽  
Author(s):  
Cheng-Hsien Wu ◽  
Yon-Cheong Wong ◽  
Being-Chuan Lin

Abstract Background: Portal vein thrombosis (PVT) was infrequently complicated by acute cholecystitis. The clinical signs of PVT are usually non-specific and subclinical. The treatment aim was to re-canalize the portal vein and to avoid serious complications. An early anticoagulation treatment would result in favorable outcome. Case Report: We present a case of acute cholecystitis with sole left portal vein thrombosis causing left liver atrophy in a 59-year-old woman.Conclusions: While the surgeon is familiar with this uncommon condition, the PVT could be detected on the pre-operative images through a tailored CT or MRI. The condition of PVT is often subclinical and might complicate liver atrophy, an early anticoagulation treatment would result in a favorable outcome.


2021 ◽  
Vol 18 (3) ◽  
pp. 105-105
Author(s):  
V. G.
Keyword(s):  

Mayer (Berlin, klirr Woch, 1921, no. 31) emphasizes the important role that hies play in the etiology of acute atrophy of the liver: out of 25 cases of his material that were submitted for autopsy, in 15 cases of his material, the previous syphilis was undoubted and in 5 - probable.


Cureus ◽  
2021 ◽  
Author(s):  
Nitin Agarwal ◽  
Manoj K Dokania ◽  
Gyan R Kumar ◽  
Dharmateja G Manda ◽  
Anil K Singh Rana

2020 ◽  
Vol 21 (12) ◽  
pp. 3647-3654
Author(s):  
Toru Miyazaki ◽  
Hiroji Shinkawa ◽  
Shigekazu Takemura ◽  
Shogo Tanaka ◽  
Ryosuke Amano ◽  
...  

2020 ◽  
Vol 8 (7-8) ◽  
pp. 670-671
Author(s):  
V. Strogonov

The author observed a case of acute yellow atrophy of the liver.


JCI Insight ◽  
2020 ◽  
Vol 5 (17) ◽  
Author(s):  
Usua Oyarbide ◽  
Arish N. Shah ◽  
Wilmer Amaya-Mejia ◽  
Matthew Snyderman ◽  
Margaret J. Kell ◽  
...  
Keyword(s):  

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