free distribution
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2022 ◽  
Vol 105 (1) ◽  
Author(s):  
Ivandson P. de Sousa ◽  
Gustavo Zampier dos Santos Lima ◽  
Eliziane G. Oliveira ◽  
Marina Henriques Lage Duarte ◽  
José A. Alves-Gomes ◽  
...  
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Author(s):  
Marcelo Ferreira

The chapter bears on the distribution and interpretation of bare nominals in Brazilian Portuguese, paying special attention to bare singulars and the number neutrality that seems to characterize them. Brazilian Portuguese displays overt plural morphology and a full range of definite and indefinite determiners, which makes the relatively free distribution of bare singulars an intriguing topic from a typological perspective. The chapter discusses some proposals and analytical tools that have been employed to account for their behaviour, as well as their theoretic implications for issues related to singular–plural, mass–count, and generic–episodic distinctions.


PLoS Medicine ◽  
2021 ◽  
Vol 18 (5) ◽  
pp. e1003590
Author(s):  
Nav Persaud ◽  
Michael Bedard ◽  
Andrew Boozary ◽  
Richard H. Glazier ◽  
Tara Gomes ◽  
...  

Background Adherence to medicines is low for a variety of reasons, including the cost borne by patients. Some jurisdictions publicly fund medicines for the general population, but many jurisdictions do not, and such policies are contentious. To our knowledge, no trials studying free access to a wide range of medicines have been conducted. Methods and findings We randomly assigned 786 primary care patients who reported not taking medicines due to cost between June 1, 2016 and April 28, 2017 to either free distribution of essential medicines (n = 395) or to usual medicine access (n = 391). The trial was conducted in Ontario, Canada, where hospital care and physician services are publicly funded for the general population but medicines are not. The trial population was mostly female (56%), younger than 65 years (83%), white (66%), and had a low income from wages as the primary source (56%). The primary outcome was medicine adherence after 2 years. Secondary outcomes included control of diabetes, blood pressure, and low-density lipoprotein (LDL) cholesterol in patients taking relevant treatments and healthcare costs over 2 years. Adherence to all appropriate prescribed medicines was 38.7% in the free distribution group and 28.6% in the usual access group after 2 years (absolute difference 10.1%; 95% confidence interval (CI) 3.3 to 16.9, p = 0.004). There were no statistically significant differences in control of diabetes (hemoglobin A1c 0.27; 95% CI −0.25 to 0.79, p = 0.302), systolic blood pressure (−3.9; 95% CI −9.9 to 2.2, p = 0.210), or LDL cholesterol (0.26; 95% CI −0.08 to 0.60, p = 0.130) based on available data. Total healthcare costs over 2 years were lower with free distribution (difference in median CAN$1,117; 95% CI CAN$445 to CAN$1,778, p = 0.006). In the free distribution group, 51 participants experienced a serious adverse event, while 68 participants in the usual access group experienced a serious adverse event (p = 0.091). Participants were not blinded, and some outcomes depended on participant reports. Conclusions In this study, we observed that free distribution of essential medicines to patients with cost-related nonadherence substantially increased adherence, did not affect surrogate health outcomes, and reduced total healthcare costs over 2 years. Trial registration ClinicalTrials.gov NCT02744963.


Mathematics ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1015
Author(s):  
Sagrario Lantarón ◽  
Mariló López ◽  
Susana Merchán ◽  
Javier Rodrigo ◽  
José Samuel Rodríguez

This article discusses a theoretical construction based on the graph theory to rework the space of potential partitions in envy-free distribution. This work has the objective of applying Sperner’s lemma to the distribution of three rotating shifts for three workers who are to cover a 24 h job position in a company. As a novel feature, worker’s preferences have been modeled as functions of probability for the three shifts, according to salary offers for said shifts. Envy-free allocation was achieved, since each worker received their preferred shift without the need for negotiation between agents in conflict. Adaptation to the type of dynamic situations that arise with rotating shifts, as well as the consideration of probabilistic preferences by workers are some of the main novelties of this work.


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