Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.

Clinical Features of Sporotrichosis

Sporotrichosis is a mycosis caused by Sporothrixschenckii complex. Generallyoccurs by traumatic inoculation. It has a wide variety of clinical presentations and can affect the skin, lungs, bones, joints and other organs. The paper reviews the current scientific literature data on sporotrichosisand the different clinical presentations. Results: Sporotrichosis is classified as primary cutaneous disease, with three main clinical presentations: lymphocutaneous, fixed-cutaneous and disseminated; and the systemic disease. The predominant form is lymphangitic sporotrichosis, which represents 60-80% of cases in Mexico.

Generalized acquired cutis laxa and urticarial dermatoses associated with қ-chain IgA micromolecular myeloma

Cutis laxa (CL) is a group of rare cutaneous disease, inherited or acquired, characterized by inelastic, redundant, wrinkled, loose skin, with loss of elasticity and features of premature aging [...].

Localized psoriasis post hand burn

The Koebner Phenomenon (KP) is the appearance of new skin lesions on previously unaffected skin secondary to trauma. This phenomenon is given the fact that the new lesions that appear are clinically and histologically identical to the patient’s underlying cutaneous disease [1].

Evaluation of Intralesional Injection of 5-fluorouracil in Treatment of Vitiligo

Background: Vitiligo is a chronic cutaneous disease characterized by depigmented patches that leave psychological impact on the patients. New treatment modalities have been developed to improve the results vitiligo with less side effects. Objective: To evaluate intralesional injection of 5-fluorouracil in treatment of vitiligo. Patients and Methods: The study included 20 localized stable vitiligo patients. Each patient was treated with intralesional injection of 5-fluorouracil every 2 weeks for 3 sessions followed by narrow band sessions twice weekly for 3 months. Results: There was statistically significant repigmentation after treatment with intralesional 5-FU (mean of 50.30 ± 34.60, P value =0.001 Wilcoxon signed ranks test between before and after). 55% of patients showed >50% repigmentation. after 3 months therapy. Side effects were minimal and transient. Conclusion: Intralesional injection of 5-FU is safe and effective in the treatment of vitiligo.