amino acid supplement
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2020 ◽  
Vol 34 (2) ◽  
Author(s):  
Jeong-Ju Yoo ◽  
Darryn Willoughby ◽  
LesLee Funderburk

The purpose of this study is to demonstrate if the combination of resistance training (RT) and an intake of amino acid supplement will have a positive impact on weight preoccupation, self-classified weight and body satisfaction. A total of 33 usable data sets were obtained from the survey among 40 women who participated in this 10-week RT program, and they were given either 5 grams of placebo or amino acid (leucine). RT and the amino acid supplement played an important role in body satisfaction overall. Determining the most effective combination of approaches to tailor recommendations for adults for optimal quality of life is crucial.


2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Melynda S. Coker ◽  
Kaylee Ladd ◽  
Josh Kim ◽  
Carl J. Murphy ◽  
Ryan DeCort ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 254
Author(s):  
Melynda S. Coker ◽  
Kaylee R. Ladd ◽  
Jimin Kim ◽  
Carl J. Murphy ◽  
Ryan DeCort ◽  
...  

Excess alcohol consumption is a top risk factor for death and disability. Fatty liver will likely develop and the risk of liver disease increases. We have previously demonstrated that an essential amino acid supplement (EAAS) improved protein synthesis and reduced intrahepatic lipid in the elderly. The purpose of this exploratory pilot study was to initiate the evaluation of EAAS on intrahepatic lipid (IHL), body composition, and blood lipids in individuals with mild to moderate alcohol use disorder (AUD). Following consent, determination of eligibility, and medical screening, 25 participants (18 males at 38 ± 15 years/age and 7 females at 34 ± 18 years/age) were enrolled and randomly assigned to one of two dosages: a low dose (LD: 8 g of EAAS twice/day (BID)) or high dose (HD: 13 g of EAAS BID). Five of the twenty-five enrolled participants dropped out of the intervention. Both groups consumed the supplement BID for 4 weeks. Pre- and post-EAAS administration, IHL was determined using magnetic resonance imaging/spectroscopy, body composition was analyzed using dual-energy X-ray absorptiometry, and blood parameters were measured by LabCorp. T-tests were used for statistical analysis and considered significant at p < 0.05. While there was no significant change in IHL in the LD group, there was a significant 23% reduction in IHL in the HD group (p = 0.02). Fat mass, lean tissue mass, bone mineral content, and blood lipids were not altered. Post-EAAS phosphatidylethanol was elevated and remained unchanged in LD at 407 ± 141 ng/mL and HD at 429 ± 196 ng/mL, indicating chronic and excess alcohol consumption. The HD of the proprietary EAAS formulation consumed BID seemed to lower IHL in individuals with mild to moderate AUD. We suggest that further studies in a larger cohort be conducted to more completely address this important area of investigation.


Author(s):  
Melynda S. Coker ◽  
Kaylee Ladd ◽  
Josh Kim ◽  
Carl J. Murphy ◽  
Ryan DeCort ◽  
...  

Excess alcohol consumption is a top risk factor for death and disability. Fatty liver will likely develop and the risk of liver disease increases. We have previously demonstrated that an essential amino acid supplement (EAAS) improved protein synthesis and reduced intrahepatic lipid in the elderly. The purpose of this study was to further evaluate the influence of EAAS on intrahepatic lipid (IHL), body composition, and blood lipids in individuals with mild to moderate alcohol use disorder (AUD). Following consent, determination of eligibility, and medical screening, 25 participants (18 males at 38&plusmn;15 years/age and 7 females at 34&plusmn;18 years/age) were enrolled and randomly assigned to one of two dosages: a low dose (LD: 8 grams of EAAS twice/day (BID)) or high dose (HD: 13 grams of EAAS BID). Both groups consumed the supplement for 4 weeks. Pre- and post-EAAS administration, IHL was determined using magnetic resonance imaging/spectroscopy, body composition was analyzed using dual energy x-ray absorptiometry, and blood parameters were measured by LabCorp. T-tests were used for statistical analysis and considered significant at P&lt;0.05. While there was no significant change in IHL in the LD group, there was a significant 23% reduction in IHL in the HD group (p=0.02). Fat mass, lean tissue mass, bone mineral content, and blood lipids were not altered. Post-EAAS phosphatidylethanol was elevated and remained unchanged in LD at 407&plusmn;141 ng/ml and HD at 429&plusmn;196 ng/ml, indicating chronic and excess alcohol consumption. Based on these results, we conclude that 13 grams of proprietary EAAS consumed BID lowers IHL in individuals with mild to moderate AUD.


2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Charmaine S. Tam ◽  
William D. Johnson ◽  
Jennifer Rood ◽  
Amy L. Heaton ◽  
Frank L. Greenway

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