astrocyte culture
Recently Published Documents


TOTAL DOCUMENTS

21
(FIVE YEARS 2)

H-INDEX

9
(FIVE YEARS 2)

2019 ◽  
Vol 131 ◽  
pp. 104538 ◽  
Author(s):  
Fabiana Galland ◽  
Marina Seady ◽  
Jessica Taday ◽  
Soraya Soubhi Smaili ◽  
Carlos Alberto Gonçalves ◽  
...  

2019 ◽  
Vol 320 ◽  
pp. 50-63 ◽  
Author(s):  
Jude Prah ◽  
Ali Winters ◽  
Kiran Chaudhari ◽  
Jessica Hersh ◽  
Ran Liu ◽  
...  

2017 ◽  
Vol 132 ◽  
pp. 10-19 ◽  
Author(s):  
Xiu Sun ◽  
Xin Hu ◽  
Dan Wang ◽  
Yimin Yuan ◽  
Shangyao Qin ◽  
...  

2016 ◽  
Vol 14 (1) ◽  
pp. 56-63 ◽  
Author(s):  
Andréia Gomes Bezerra ◽  
Giuseppina Negri ◽  
Joaquim Maurício Duarte-Almeida ◽  
Soraya Soubhi Smaili ◽  
Elisaldo Araújo Carlini

ABSTRACT Objective To evaluate the phytochemical composition of hydroethanolic extracts from powdered aerial parts of Turnera diffusa Willd (Turneraceae; T. diffusa), as well as its toxicity in astrocytes. Methods Chemical analyses of hydroethanolic extract from powdered aerial parts ofT. diffusa were carried out using HPLC-DAD-ESI-MS/MS.In vitro assays using astrocytes culture were performed to evaluate cell death. Results Flavone-C, O-diglycosides, such as, luteolin-8-C-[6-deoxy-2-O-rhamnosyl]-xylo-hexos-3-uloside, apigenin-8-C-[6-deoxy-2-O-rhamnosyl]-xylo-hexos-3-uloside and apigenin-7-O-6”-p-coumaroylglucoside were the main compounds found in this hydroethanolic extract. Concentration time-effect demonstrated the toxicity of this extract at a concentration of 1,000µg/mL in astrocyte culture, after 6 and 24 hours of incubation. Conclusion In phytochemical analyses, important antioxidants (mainly flavonoids) were observed. T. diffusa extracts presented cytotoxic effect in high concentrations, leading to increased cell death in astrocyte culture.


2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Josiane Campos Cruz ◽  
Milene Mantovani Lopes ◽  
Lucila Leico Kagohara Elias ◽  
José Antunes‐Rodrigues

2011 ◽  
Vol 150 (1) ◽  
pp. 95-102 ◽  
Author(s):  
S. Yoshiba-Suzuki ◽  
J.-i. Sagara ◽  
S. Bannai ◽  
N. Makino

Sign in / Sign up

Export Citation Format

Share Document