Pulmonary Manifestation
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Lamia Bengherbia ◽  
Said Taharboucht ◽  
Nadia Touati ◽  
Oussama Souas ◽  
Ahcene Chibane

2021 ◽  
Vol 11 (6) ◽  
pp. 686
Tom Wai-Hin Chung ◽  
Hui Zhang ◽  
Fergus Kai-Chuen Wong ◽  
Siddharth Sridhar ◽  
Kwok-Hung Chan ◽  

Non-conductive olfactory dysfunction (OD) is an important extra-pulmonary manifestation of coronavirus disease 2019 (COVID-19). Olfactory bulb (OB) volume loss and olfactory network functional connectivity (FC) defects were identified in two patients suffering from prolonged COVID-19-related OD. One patient received olfactory treatment (OT) by the combination of oral vitamin A and smell training via the novel electronic portable aromatic rehabilitation (EPAR) diffusers. After four-weeks of OT, clinical recuperation of smell was correlated with interval increase of bilateral OB volumes [right: 22.5 mm3 to 49.5 mm3 (120%), left: 37.5 mm3 to 42 mm3 (12%)] and improvement of mean olfactory FC [0.09 to 0.15 (66.6%)].

2021 ◽  
Azadeh Mottaghi ◽  
Maryam Roham ◽  
Mahin Jamshidi Makiani ◽  
Mitra Ranjbar ◽  
Azadeh Laali ◽  

Abstract Background: COVID-19 is a new emerging disease that causes a pandemic situation in the world. Corona virus can enter into the body via several ways and it damages other organs of the body in addition to the respiratory system. This study aimed at verifying extra-pulmonary manifestation of COVID-19.Methods: The present study was done as cross-sectional in the single center from March 1 to May 1 2020 at Firoozgar educational hospital in Tehran, Iran. 107 patients with confirmed Covid-19 pneumonia according to WHO interim guidance were recruited in this study. Extra-pulmonary manifestations of COVID-19 were recorded. SPSS, version 26 was used for all analyses.Results: The mean (SD) and median of age was 59.3 (17.4) and 62.0 respectively and 58 (54.2%) were men. Body temperature of patients who were equal or less than 60 years was significantly higher than other patients (39.02 vs. 38.08, p=0001). The most common extra-pulmonary manifestation was GI symptoms included nausea, vomiting, abdominal pain, diarrhea, Hepatocellular LFT abnormality, Cholestatic LFT abnormality and Amylase lipase incensement (37 patients (34.6%)). Ophthalmological, cardiac, neurological and dermatological manifestations were shown in 6.5%, 6.5%, 14.9% and 14.0% of patients respectively. Conclusion: Investigating the clinical and radiological symptoms of COVID-19 showed that SARS-CoV-2 infection may also be associated with extrapulmonary symptoms. Therefore, clinicians and radiologists should be familiar with such symptoms of this disease.

Lupus ◽  
2020 ◽  
pp. 096120332096743
Ritasman Baisya ◽  
Phani Kumar Devarasetti ◽  
Shantveer G Uppin ◽  
Ramakrishna Narayanan ◽  
Liza Rajasekhar ◽  

Objective Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinico-patho-radiological diagnosis which rarely presents as a pulmonary manifestation of lupus. In this concise report, organizing pneumonia was found as the sole pulmonary manifestation of SLE in different age groups. Method All three patients diagnosed with SLE according to SLICC 2012 classification criteria, were admitted in rheumatology ward of NIMS hospital, Hyderabad, India from May to November, 2018. Their diagnosis of BOOP was either biopsy proven or imaging guided. Review of literature was done with MeSH terms (SLE, BOOP) in PubMed and approximately 10 articles were reviewed including latest of 2019 published in Scientific Reports. Result There were three patients – one juvenile lupus and two adults. Two patients were male and one female. All three patients had SLE with high disease activity. They all had organising pneumonia as pulmonary manifestation with other organ involvement. Juvenile patient had a fatal outcome while the others had a good recovery with steroid and immunosuppressive. Conclusion BOOP is a rare pulmonary manifestation in lupus. It can be diagnosed early with more precision using computerised tomography of lung without waiting for biopsy report. This will result in a better prognosis by rapid initiation of corticosteroid and immunosuppressive treatment.

2020 ◽  
Vol 8 (8) ◽  
Qusay Jummaa Lazim ◽  
Sinan Shakir Gheni Atrah ◽  
Khalid Jawad Mutlag ◽  
Haider Saadoon Qasim Alhilfi ◽  
Ahmed Muhi Fahad ◽  

2020 ◽  
pp. 1-2
Pearl Esther Minz ◽  
Lalita Khess ◽  
Dinesh Chandra Sawaiyan

Tuberculous lymphadenitis is the most common extra pulmonary manifestation of tuberculosis. FNAC and Ziehl Neelson staining of FNA samples have low specificity and sensitivity respectively. The aim of this study is to correlate the cytomorphological pattern of the lymph nodes with CB-NAAT as an aid to the diagnosis of tuberculous lymphadenitis. Materials and methods-A retrospective study of 58cases were undertaken from January2019 to Decamber2019 in RIMS Ranchi, a tertiary care centre .Result- Out of the total 58cases 52 samples could be run on CB-NAAT. Out of the total cases run [56%] were CB-NAAT positive. The cytomorphological pattern, Necrosis without epithelial aggregates showed the maximum positivity of MTB CB-NAAT being [35%] . The preponderance of males and age group between 21to 30 years was the highest [57%]. Rifampicin resistance was seen in [14%] of cases.

2020 ◽  
Vol 56 (7) ◽  
pp. 468-469
Virginia Guevara Velázquez ◽  
José María González Ruiz ◽  
Elena García Arias-Salgado ◽  
Rosa Cordovilla Pérez ◽  
Miguel Iglesias Heras ◽  

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