blood testing
Recently Published Documents


TOTAL DOCUMENTS

606
(FIVE YEARS 93)

H-INDEX

44
(FIVE YEARS 3)

Author(s):  
Somy Charuvila ◽  
Tasmiah Tahera Aziz ◽  
Sarah E. Davidson ◽  
Ummay Naznin ◽  
Shiuly Sinha ◽  
...  

Abstract Background Paediatric anaemia is highly prevalent in low–middle-income countries and can negatively impact postoperative outcomes. Currently, there are no guidelines for the management of paediatric preoperative anaemia. To ensure optimal care in resource-limited settings: balancing the risks of anaemia and using resources such as blood transfusion, we first need to understand current practices. To address this, a joint UK–Bangladesh team conducted an observational study at a paediatric surgical centre in Bangladesh. Methods A total of 464 patients ≤16 years who underwent elective and emergency surgery were categorised into major (351/464), moderate (92/464) and minor (21/464) surgery groups according to anticipated blood loss. Preoperative anaemia testing and transfusion was assessed retrospectively through patient notes. Results Median age was 4 years and 73% were male. 32.5% (151/464) patients had preoperative blood testing for anaemia. 17.5% (81/464) children were transfused preoperatively. Of those children transfused, 40.7% (33/81) underwent transfusion solely based on visible signs of anaemia on clinical examination. Seventy-five percentage (36/48) of children who underwent transfusion after blood testing had haemoglobin ≥80 g/L. Major surgery category had the highest proportion of children who were transfused and tested for anaemia. Conclusion A liberal transfusion approach is evident here. Discussion with local clinicians revealed that this was due to limitations in obtaining timely blood results and reduction in laboratory costs incurred by families when clinical suspicion of anaemia was high. Further research is needed to analyse the potential of using bedside haemoglobin testers in conjunction with patient blood management strategies to limit blood transfusions and its associated risks.


2021 ◽  
Vol 4 (12) ◽  
pp. e2140644
Author(s):  
Jingjing Zhang ◽  
Xun Tian ◽  
Ye Chen ◽  
Sisi Huang ◽  
Zifeng Cui ◽  
...  

2021 ◽  
Vol 96 (6) ◽  
pp. 484-492
Author(s):  
Young Sang Lyu ◽  
Jin Hwa Kim ◽  
Sang Yong Kim

Hypoglycemia is common but can lead to life-threatening consequences. Accurate diagnosis is important to establish the appropriate treatment strategy. Most cases of hypoglycemia are caused by hypoglycemic agents, although it can occur in individuals without diabetes. A systemic and comprehensive diagnostic approach is required to diagnose hypoglycemia in patients without diabetes. It is important to perform appropriate blood testing during an episode of hypoglycemia. This review will focus on the definition, differential diagnosis, causes, and treatment of hypoglycemia, particularly in people without diabetes.


2021 ◽  
Author(s):  
Keiko Suzuki ◽  
Takaya Ichikawa ◽  
Satoshi Suzuki ◽  
Yoko Tanino ◽  
Yasutaka Kakinoki

Background It is critical for clinicians seeing outpatients with coronavirus disease 2019 (COVID-19) to identify those who will require oxygen therapy after the hospital visit. Although many studies on biomarkers predicting the study outcomes, including intensive care unit admission, ventilator requirement, or mortality, in hospitalized patients with COVID-19 have been conducted, research on biomarkers predicting the need for oxygen therapy in outpatients is sparse. Methods Patients with COVID-19 who visited Asahikawa City Hospital on an outpatient basis were included in the study. In total, 287 new outpatients visited between April 2021 and September 2021, and 142 underwent blood testing. All blood tests were performed before any treatments for COVID-19 were started. Demographic information, laboratory data, and clinical treatment information were extracted from the electronic medical records. Risk factors associated with oxygen therapy were explored. Results In total, 40 of 142 patients who underwent blood testing required oxygen therapy within 7 days after blood samples were taken, and all other patients recovered without oxygen therapy. C-reactive protein (CRP) and lactate dehydrogenase (LDH) levels were significantly higher in patients who required oxygen therapy, and their cutoffs were 36 mg/L (sensitivity, 0.802; specificity, 0.725) and 267 U/L (sensitivity, 0.713; specificity, 0.750), respectively. Multivariate logistic regression identified age, body mass index, CRP ≥ 36 mg/L, and LDH ≥ 267 U/L as significant risk factors for oxygen therapy. Conclusion This study suggests that elevated CRP and LDH levels are useful biomarkers for predicting the need for oxygen therapy in outpatients with COVID-19. Further confirmatory studies are needed.


Transfusion ◽  
2021 ◽  
Author(s):  
Laura Tonnetti ◽  
Roger Y. Dodd ◽  
Gregory Foster ◽  
Susan L. Stramer

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi12-vi12
Author(s):  
Arthur van der Boog ◽  
Fia Cialdella ◽  
Danique Bruil ◽  
Karlijn Smitt ◽  
Filip de Vos ◽  
...  

Abstract BACKGROUND A combination of clinical characteristics, radiological findings and tissue markers is used in the assessment of glioblastoma prognosis and prediction of treatment response. The value of routine blood tests as a tool of prognosis has been a subject of debate. In addition to increased complication rate in subsequent resections and radiological uncertainty in treatment monitoring, there is a need to monitor tumor markers in a minimally invasive manner, as molecular characterization becomes more important in the management of glioblastoma. The objective of this review is to evaluate the prognostic value of any blood marker during the course of disease and treatment in glioblastoma. METHODS We researched Pubmed and Embase for clinical studies including cohort studies and randomized controlled trials that included at least 10 adult patients and blood testing during course of disease. We extracted data on clinically relevant endpoints, i.e. overall survival (OS) or progression-free survival (PFS), in accordance with the PRISMA statements. RESULTS The search strategy yielded 6389 unique articles, of which 150 met the inclusion criteria. 37 studies found an association between survival outcomes and pre-operative markers including complete blood count (erythrocytes and leukocytes with differentiation characteristics), inflammatory markers (erythrocyte sedimentation rate and C-reactive protein), coagulability markers (prothrombin time, activated partial thromboplastin time and D-dimer), albumin, lactate dehydrogenase and glucose. Furthermore, 10 studies reported a correlation between changes in platelets, erythrocytes and leukocytes during course of disease and treatment and OS. Finally, serum and plasma levels of markers including various proteins, microRNAs and microvesicles were associated with PFS and OS. CONCLUSION The results of this study suggest that routine and specialized blood tests provide additive information on OS and PFS in glioblastoma. These promising findings highlight the need for further investigation of blood testing for biomarker evaluation.


Author(s):  
Fiqhy Bismadhika ◽  
Nunung Nurul Qomariyah ◽  
Ardimas Andi Purwita

2021 ◽  
Author(s):  
Nicola Keay ◽  
Martin Lanfear ◽  
Gavin Francis

BACKGROUND Dancers can be at risk of developing intentional and/or unintentional relative energy deficiency in sport (RED-S). Early identification of those at risk is important in prevention. OBJECTIVE The purpose of this study was to assess the effectiveness of interactive monitoring of professional dancer health with a variety of subjective and objective monitoring methods and delivering swift personalised clinical advice. METHODS Dancers from a ballet company completed a published, online dance-specific health questionnaire. Over the study period, dancers recorded wellbeing and training metrics, with menstrual cycle tracking and capillary blood testing for the recognised indicators of low energy availability. At regular, virtual clinical discussions with each dancer, findings were discussed and personalised advice given. RESULTS Twenty dancers participated in the study (mean age 26.2 years, SD 3.7), comprising 14 females (mean age 25.5 years, SD 3.7) and 6 males (mean age 27.7 years, SD 2.4). Ten of the female and all the male dancers recorded positive scores on the dance health questionnaire, suggesting a low risk of relative energy deficiency in sport (RED-S). Two female dancers were taking hormonal contraception. Apart from one, all female dancers not on hormonal contraception reported current eumenorrhoeic status. Blood testing confirmed the low risk of insufficient energy availability across the group, apart from female dancers with negative questionnaire scores. The initiative of monitoring menstrual cycles and on demand virtual clinical support was well received by dancers, healthcare and artistic staff. CONCLUSIONS Multimodal monitoring facilitated delivery of prompt personalised clinical medical feedback specific for dance. This interactive strategy permitted the early identification and swift management of emergent clinical issues. Dancers highly rated the new monitoring modalities and opportunity to discuss health and well-being, in confidence, with a doctor conversant in dance.


Sign in / Sign up

Export Citation Format

Share Document