Role of Amine Neurotransmitters and Their Receptors in Skin Pigmentation: Therapeutic Implication

Skin pigmentation can occur due to increased melanin, including melanocyte proliferation, melanin biosynthesis, or melanocyte migration. There are many factors that influence the melanin production process, but the role of neurotransmitters in this process is still unclear. We found that histamine and serotonin influence the different stages of melanogenesis and melanogenesis, which increase melanogenesis. Since then, several related papers have been published, and from these papers, it has been recognised that the role of neurotransmitters in skin-pigment-related diseases needs to be summarised. By introducing the role of neurotransmitters in the regulation of various pigment disorders, including vitiligo and melasma, through this review, many researchers can be expected to try to apply neurotransmitter-related agonists and antagonists as treatments for skin pigment disorders.

Chloasma uterinum

Chloasma uterinum consists of an abnormal deposition of skin pigment without dysfunction of the skin in the epidermis itself or immediately below it, and appears as large yellowish or blackish-brown spots on the face and trunk. Patients are almost always sure that they suffer from the liver and with complaints of an abnormal liver go to the doctor. It is very rare to observe the appearance of chloasma before puberty or after menopause. Usually it develops in the prime of sexual activity.

Ultrafast spectral hole burning reveals the distinct chromophores in eumelanin and their common photoresponse

Seeing the colors in black: ultrafast transient hole burning spectroscopy reveals the absorption properties of discrete chromophores and their interactions in the skin pigment eumelanin.

THE EFFICIENCY OF DYE-SENSITIZED SOLAR CELL (DSSC) IMPROVEMENT AS A LIGHT PARTY TiO2-NANO PARTICLE WITH EXTRACT PIGMENT MANGOSTANA PEEL (Garcinia Mangostana) WITH VARIOUS SOLVENTS

The dye-sensitized solar cell (DSSC) is one of the photochemical electrical cells consisting of a photoelectrode, dye, electrolyte, and counter electrode. The purpose of using dyes in the DSSC is to extend the absorption spectrum to visible light because visible light has about 96% energy from sunlight. This article presents some experimental data on the nature of absorbance and the conductivity of natural dyes extracted from the plant as an application in the DSSC. Absorbance test using Spectrophotometer UV Visible 1601 PC and electrical properties test using Elkahfi 100 / Meter I-V. DSSC fabrication has been done using dye extract of mangosteen skin pigment (Garcinia mangostana) with a variety of coating technique of Spin Coating and Slip Casting. The results show that natural dyes from natural material extraction have an absorbance spectrum of 380-520 nm range and the greatest conductivity is owned by mangosteen fruit skin pigment (Garcinia mangostana). From the results of the test using AM Simulator 1.5G (100 mW / cm2) diesel simulator, it was found that the volume of TiO2 precursors affected the performance of DSSC solar cells and the overall conversion efficiency was 0.084% for the mangosteen skin dye by slip casting technique and 0.092% for the mangosteen skin dye by spin coating technique.