Perché I Medici Parlano Ancora Il Greco?

Although the extraordinary progress in medicine since the 19th century has made Hippocrates and Galen irrelevant, Greek and Greek-derived terms continue to be used in the medical sciences today. The marked ability of the Greek language to form compounds facilitated the expansion of its medical lexicon. Greek medicine evolved far longer than its modern counterpart; its enduring cachet has lent it an atemporality. This article traces the main stages in the history of the nearly continuous reception of Greek medical nomenclature across more than two millennia. The process is shown to have been inseparable from the transmission and editing of Greek medical texts and their translation into Latin, Arabic, and eventually into vernacular languages. The article also sheds incidental light on the history of translation and transliteration in Europe and the Arab world.

New Serbian records of the slug Tandonia kusceri (H. Wagner, 1931) (Gastropoda: Eupulmonata: Milacidae) suggest its continuous dispersal to the north

Tandonia kusceri (H. Wagner) is a terrestrial slug native to the Balkan Peninsula (S. Serbia, N. Macedonia, Bulgaria and Dobrudja region of Romania) and the European part of Turkey. In Serbia, it was known mostly from the southern regions. The northernmost locality (Palić settlement, near Subotica) reported here suggests that the slug’s distribution is nearly continuous from its native range until Slovakia. The new record was first recognised from the pictures posted on a Facebook group for insect identification in 2021. The identification was subsequently confirmed by anatomical examination. This further emphasises the importance of social media in monitoring the spread of invasive invertebrates.

Duration of Downy Mildew Control Achieved with Fungicides on Cucumber under Florida Field Conditions

Cucurbit production in Florida is impacted by downy mildew on a yearly basis. Cucurbit downy mildew (CDM), caused by Pseudoperonospora cubensis, is one of the most devastating cucurbit diseases and can lead to complete yield loss. Nearly continuous production of cucurbits occurs temporally throughout Florida, which puts extensive pressure on the pathogen population to select for individuals that are resistant to current fungicides labeled for CDM. Loss of efficacy due to fungicide resistance developing is becoming a major concern for Florida cucurbit growers who rely on these products to manage CDM. This study was established to evaluate the field activity of eleven currently utilized fungicides by determining their duration of activity when applied at various intervals for the management of CDM in cucumber under Florida field conditions. By comparing levels of percent CDM control and area under the disease progress curve (AUDPC) values, the fungicide’s duration of field activity was established. Field activities were less than one week for dimethomorph and fluopicolide; one week for cymoxanil; one to two weeks for chlorothalonil and mancozeb; two weeks for ethaboxam; two to three weeks for propamocarb , cyazofamid, and ametoctradin + dimethomorph; and two to four weeks for oxathiapiprolin and fluazinam. Knowledge of duration of field activity can potentially improve the development of CDM management programs and slow resistance selection.

Comparative Clinical Effectiveness of Population‐Based Atrial Fibrillation Screening Using Contemporary Modalities: A Decision‐Analytic Model

Background Atrial fibrillation (AF) screening is endorsed by certain guidelines for individuals aged ≥65 years. Yet many AF screening strategies exist, including the use of wrist‐worn wearable devices, and their comparative effectiveness is not well‐understood. Methods and Results We developed a decision‐analytic model simulating 50 million individuals with an age, sex, and comorbidity profile matching the United States population aged ≥65 years (ie, with a guideline‐based AF screening indication). We modeled no screening, in addition to 45 distinct AF screening strategies (comprising different modalities and screening intervals), each initiated at a clinical encounter. The primary effectiveness measure was quality‐adjusted life‐years, with incident stroke and major bleeding as secondary measures. We defined continuous or nearly continuous modalities as those capable of monitoring beyond a single time‐point (eg, patch monitor), and discrete modalities as those capable of only instantaneous AF detection (eg, 12‐lead ECG). In total, 10 AF screening strategies were effective compared with no screening (300–1500 quality‐adjusted life‐years gained/100 000 individuals screened). Nine (90%) effective strategies involved use of a continuous or nearly continuous modality such as patch monitor or wrist‐worn wearable device, whereas 1 (10%) relied on discrete modalities alone. Effective strategies reduced stroke incidence (number needed to screen to prevent a stroke: 3087–4445) but increased major bleeding (number needed to screen to cause a major bleed: 1815–4049) and intracranial hemorrhage (number needed to screen to cause intracranial hemorrhage: 7693–16 950). The test specificity was a highly influential model parameter on screening effectiveness. Conclusions When modeled from a clinician‐directed perspective, the comparative effectiveness of population‐based AF screening varies substantially upon the specific strategy used. Future screening interventions and guidelines should consider the relative effectiveness of specific AF screening strategies.

Resistance of Austenitic Stainless Steels to Ductility-Dip Cracking: Mechanisms

In Ni-based alloys, precipitates that form along grain boundaries (GBs) during terminal solidification have been shown to pin GBs and resist GB sliding, which can cause ductility-dip cracking (DDC). As a result, it is often suggested that the stainless steel skeletal/lacy  in a  matrix resists DDC because it pins GBs. In the present study, austenitic stainless steels 304, 316, 310, and 321 were quenched with liquid Wood’s metal (75˚C) during welding. Quenching captured the elevated-temperature micro-structure and simultaneously induced cracking, thus revealing the mechanisms of the resistance to DDC. In addition, DDC was much higher in 310 than 304, 316, and 321, which is consistent with results of conventional tests. Both 304 and 316 solidified as columnar  grains, with continuous  formed along GBs soon after solidification to resist DDC along the GBs. 321 solidified as equiaxed grains of  instead of columnar, and the tortuous GBs associated with equiaxed grains resisted DDC. 310, however, solidified as coarse, straight  grains with little  along the GBs, and solidification GBs migrated to become locally straight. The resulting GBs were long, straight, and naked, which is ideal for DDC. In 304, 316, or 321, skeletal/lacy  in a  matrix did not exist in the fusion zone near the mushy zone, where DDC occurs. This proved skeletal/lacy  cannot resist DDC as often suggested. Instead, the present study identified two new mechanisms of resistance to DDC: 1) formation of continuous or nearly continuous  along boundaries of columnar  grains and 2) solidification as equiaxed  grains.

Field Theoretical Approach for Signal Detection in Nearly Continuous Positive Spectra I: Matricial Data

Renormalization group techniques are widely used in modern physics to describe the relevant low energy aspects of systems involving a large number of degrees of freedom. Those techniques are thus expected to be a powerful tool to address open issues in data analysis when datasets are highly correlated. Signal detection and recognition for a covariance matrix having a nearly continuous spectra is currently one of these opened issues. First, investigations in this direction have been proposed in recent investigations from an analogy between coarse-graining and principal component analysis (PCA), regarding separation of sampling noise modes as a UV cut-off for small eigenvalues of the covariance matrix. The field theoretical framework proposed in this paper is a synthesis of these complementary point of views, aiming to be a general and operational framework, both for theoretical investigations and for experimental detection. Our investigations focus on signal detection. They exhibit numerical investigations in favor of a connection between symmetry breaking and the existence of an intrinsic detection threshold.

Context-dependent behavioural plasticity compromises disruptive selection of sperm traits in squid

Sperm morphology is generally uniform within a species due to selective pressures that act to achieve better fertilization outcomes under postcopulatory competitive circumstances. Therefore, polyandry that intensifies post-mating sperm competition should constrain intraspecific sperm polymorphism. Contrary to this paradigm, we previously found that a polyandrous squid, Heterololigo bleekeri, produces dimorphic eusperm (flagellum length dimorphism; FLD), which is closely associated with alternative reproductive tactics (ARTs); large males (consorts) transfer their spermatophores inside the female’s mantle cavity, while small males (sneakers) do so outside the mantle. Thus, FLD was considered as the consequence of different insemination strategies that arise from different modes of sperm competition, sperm storage and the fertilization environment. However, in other squid species showing ARTs, the choice of mating behaviour is rather conditional (i.e., switching mating tactic between consorts and sneakers), which poses the question of whether sperm FLD could have evolved. Here, we investigated five species in the family Loliginidae that exhibit ARTs and found that all species showed sneaker-biased FLD. However, in a species with conditional ARTs, we found FLD rather ambiguous and the testicular somatic index to be nearly continuous among individuals at transitional state, suggesting that plasticity in mating behaviour compromises the disruptive selection on a sperm morphological trait.

Semi-Centennial of Landsat Observations & Pending Landsat 9 Launch

The first Landsat was placed in orbit on 23 July 1972, followed by a series of missions that have provided nearly continuous, two-satellite 8-day repeat image coverage of the Earth's land areas for the last half-century. These observations have substantially enhanced our understanding of the Earth's terrestrial dynamics, both as a major element of the Earth's physical system, the primary home of humans, and the major source of resources that support them. The history of Landsat is complex, reflective of the human systems that sustain it. Despite the conflicted perspectives surrounding the continuation of the program, Landsat has survived based on worldwide recognition of its critical contributions to understanding land dynamics, management of natural resources and Earth system science. Launch of Landsat 9 is anticipated in Fall 2021, and current planning for the next generation, Landsat Next is well underway. The community of Landsat data users is looking forward to another 50 years of the Landsat program.

Ancient diversity and turnover of cunninghamioid conifers (Cupressaceae): two new genera from the Upper Cretaceous of Hokkaido, Japan

Conifers of the taxodiaceous grade of Cupressaceae were more diverse and widespread during the Mesozoic than they are today. The earliest diverging subfamily, Cunninghamioideae, only includes a single extant genus, but has at least 10 fossil genera. Here, two additional cunninghamioid genera are characterized on the basis of permineralized seed cones from the Upper Cretaceous of Hokkaido, Japan. These conifers display seed cone characters typical of cunninghamioids; however, they have a mosaic of characters that are not seen in any reported conifer of Cupressaceae. They are, therefore, designated as two new extinct species: Ohanastrobus hokkaidoensis gen. et sp. nov. and Nishidastrobus japonicum gen. et sp. nov. These newly reported conifers expand the taxonomic and morphological diversity of cunninghamioids. The stratigraphic and paleobiogeographic records of cunninghamioids and other fossil Cupressaceae with foliate seed cones indicate they peak in diversity during the Cretaceous. The living genera Taiwania and Cunninghamia appear during the Albian and Campanian, respectively, and maintain a nearly continuous fossil record through to today, while nearly all other extinct genera of Cupressaceae with foliate cones disappear by the close of the Campanian. As more ancient cunninghamioids are recovered, our understanding of macroevolutionary patterns of this once diverse lineage will be further elucidated.

A long-term record of early to mid-Paleozoic marine redox change

The extent to which Paleozoic oceans differed from Neoproterozoic oceans and the causal relationship between biological evolution and changing environmental conditions are heavily debated. Here, we report a nearly continuous record of seafloor redox change from the deep-water upper Cambrian to Middle Devonian Road River Group of Yukon, Canada. Bottom waters were largely anoxic in the Richardson trough during the entirety of Road River Group deposition, while independent evidence from iron speciation and Mo/U ratios show that the biogeochemical nature of anoxia changed through time. Both in Yukon and globally, Ordovician through Early Devonian anoxic waters were broadly ferruginous (nonsulfidic), with a transition toward more euxinic (sulfidic) conditions in the mid–Early Devonian (Pragian), coincident with the early diversification of vascular plants and disappearance of graptolites. This ~80-million-year interval of the Paleozoic characterized by widespread ferruginous bottom waters represents a persistence of Neoproterozoic-like marine redox conditions well into the Phanerozoic.