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Revista Fitos ◽  
2021 ◽  
Vol 15 (4) ◽  
pp. 444-455
Author(s):  
Carlos Rocha Oliveira ◽  
Leonardo Mendes Bella ◽  
Marília Cristina Duarte ◽  
Rodolfo de Paula Vieira

The study evaluated the effects of essential oil from Cymbopogon martini (CMEO) on lipopolysaccharide (LPS)-stimulated human fibroblasts. Samples were collected in Monte Verde, Minas Gerais, Brazil and analyzed by gas chromatography with mass spectrometry. The fibroblasts were cultured in a monolayer using Iscove's medium and stimulated by LPS (1 μg/mL) and incubated for 24 h at 37°C. The cytotoxicity was evaluated by MTT assay and collagen concentration by Sirius red. Collagenase activity, hyaluronic acid, and the concentrations of IL-1β; IL-6; MCP-1 (CCL2), and MIP-1-α (CCL3) were evaluated. The effect of CMEO on the expression of mRNA and the secretion of enzymes in fibroblasts were evaluated by RT-qPCR and ELISA, respectively. CMEO was cytotoxic against fibroblasts, in which 10 μg/mL inhibited 50% of cell viability. When treated with CMEO, the fibroblasts produced more collagen and hyaluronic acid than control cells. When stimulated by LPS, fibroblasts exhibited higher production of IL-6, IL-1β, MCP-1, and MIP-1α than control cells. The study demonstrated the effects of CMEO on the modulation of mediators related to inflammation and decreasing the mRNA and secretion levels of metalloproteinases, revealing to be a promising candidate for anti-aging effects and wound healing treatments.


2021 ◽  
Vol 15 (56) ◽  
pp. 596-611
Author(s):  
Hadassa Landherr Friske ◽  
Geisiely Dosso Karnoski de Jesus
Keyword(s):  

A pesquisa procurou analisar a previsão orçamentária e a arrecadação dos municípios de Alta Floresta, Apiacas e Nova Monte Verde entre os anos de 2015 e 2020, apresentando conceitos e dados tabulados a fim de verificar a efetividade da previsão orçada pelas referidas cidades. Adotou, o método de pesquisa descritiva com caráter quantitativo, utilizando-se de dados secundários e pesquisas documentais e bibliográficas empregando um corte longitudinal de 5 anos. Os dados foram obtidos pelo Portal da Transparência de cada município e evidenciam, de modo geral que, houve oscilações nos valores orçados e arrecadados, porém que os municípios vêm aprimorando o processo no decorrer dos últimos anos e apresentaram resultados mais próximos ao ideal, a equivalência de valores.


2021 ◽  
Author(s):  
◽  
Diana Fiori Rubim ◽  
Fernanda Deister Moreira ◽  
Marina Alonso ◽  
Raquel Machado Miranda ◽  
...  
Keyword(s):  

2020 ◽  
Vol 17 (34) ◽  
pp. 392-420
Author(s):  
Deivison Do Couto Gonçalves ◽  
Alexandre Pinto Coelho de Almeida ◽  
Patricia Fernanda Carvalho De Sousa

O objetivo deste relatório é apresentar o contexto de ocupação humana identificado no Complexo Eólico Monte Verde, no escopo do Projeto de Avaliação de Impacto ao Patrimônio Arqueológico (PAIPA) do Complexo Eólico Monte Verde, municípios de Jandaíra, Pedro Avelino e Lajes/RN – processo IPHAN 01421.000088/2019-90 (ARCADIS, 2019a), executado pela empresa Arcadis, iniciado em maio de 2019 e concluídos em dezembro do mesmo ano. Abstract: This article aims the presentation of the prehistoric human occupation identified at the Monte Verde Windfarm, during the execution of the Archaeological Heritage Impact Evaluation Project for the Monte Verde Windfarm, being implanted in the state of Rio Grande do Norte, Brazil. The Impact Evaluation Project occurred between may and December of 2019 and was conducted by the Archaeology team of Arcadis Brazil, part of Arcadis - Design Consultancy for natural and built assets.


PaleoAmerica ◽  
2020 ◽  
pp. 1-6
Author(s):  
Tom D. Dillehay ◽  
Mario Pino ◽  
Carlos Ocampo

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