A comparative study of suction blister epidermal grafting and automated blister epidermal micrograft in stable vitiligo

The automated blister epidermal micrograft (ABEM) is a newly introduced surgical transplantation for refractory vitiligo. Comparative analysis of other surgical methods is lacking. We conducted a retrospective study to compare the efficacy, safety, and experience of ABEM with conventional suction blister epidermal graft (SBEG). A total of 118 anatomically based vitiligo lesions from 75 patients were included. The primary outcome was the degree of repigmentation; the patient and operator experience were evaluated. SBEG had a significantly greater incidence of repigmentation (p < 0.001), as measured by the Physician Global Assessment, as well as improvements in the Vitiligo Area Scoring Index, particularly on the face/neck area (p < 0.001). ABEM, on the contrary, had reduced donor harvest time, a better patient operative experience, and more significant Dermatology Life Quality Index improvements. In a subgroup of 38 lesions from ten patients who received both SBEG and ABEM concomitantly, there was no difference in the degree of repigmentation in the same recipient area. Overall, the degree of repigmentation for SBEG is higher than ABEM, especially in the mobilized region, and the cost is less expensive. On the contrary, ABEM requires less procedure learning curve and can supply a greater transplanting zone with shorter donor site recovery. Understanding the benefits and drawbacks of two blister grafting procedures is essential for optimal surgical outcomes for vitiligo grafting.

The OPTIMIZATION OF THE IMPROVEMENT OF STUDENTS’ MATHEMATICAL LEARNING OUTCOMES BY USING THE INSTRUCTIONAL SYSTEM DEVELOPMENT PROCEDURE LEARNING MODEL (PPSI) IN SMP IT BAITUL QURAN LANGSA

This Classroom Action Research was aims to improve students' mathematical learning completeness through the instructional system development procedures learning model (PPSI). The research was implemented in Baitul Quran Junior High School in Langsa during the even semester of 2019-2020 Academic Year. The population of this study was all students of grade 8th at Baitul Quran Junior High School which amount 7 (seven) students, where the whole students were included into the sample of research. The direct sampling technique was used in this study related to the small number of population (<10). The data were collected by using pre-test and post-test method for the main and documentation as complementary. The data analysis shows that only two students on the pre-test or initial test which obtained more than 70 (Minimum completeness criteria) or around 28.57%. The post-test shows that students' mathematical learning completeness after the implementation of PPSI were increase to 5 students who got a value of more than 70 (Minimum completeness criteria) or around 85.71%. So that from the analysis of pre-test and post-test data it can be concluded that the use of instructional system development procedure learning model (PPSI) in Baitul Quran Junior High School can improve the students’ mathematical skill.

Comparison of active learning models in schools in increasing the cognitive value of students

The term learning model is distinguished from the term learning strategy, method learning or learning procedure. The term learning model has broader meaning than a strategy, approach, method or procedure. Learning models are patterns of interaction between students, teachers, and material learning that includes strategies, approaches, methods and techniques learning. Elaborate that learning strategies are tactics or tips planned by the teacher related to the whole preparation of learning can be achieved effectively. While the approach is the way taken by the teacher in the implementation of learning so that the active ideas presented can be adapted to then be understood by students. There are two types of active learning, namely: a methodological approach and material approach. Methodological approach concerns the way students Adapting the active ideas presented into their cognitive structures that are in line in the way taken by the teacher in presenting learning materials the. Examples of methodological approaches are intuitive, analytic, synthetic, spiral, inductive, deductive, thematic, realistic and heuristic. The result of this research is the material approach able to present an active concept through other active concepts already owned by students. The example presents the concept of addition with using the number line or set approach.

Emergence of stable striatal D1R and D2R neuronal ensembles with distinct firing sequence during motor learning

The dorsolateral striatum (DLS) is essential for motor and procedure learning, but the role of DLS spiny projection neurons (SPNs) of direct and indirect pathways, as marked, respectively, by D1 and D2 receptor (D1R and D2R) expression, remains to be clarified. Long-term two-photon calcium imaging of the same neuronal population during mouse learning of a cued lever-pushing task revealed a gradual emergence of distinct D1R and D2R neuronal ensembles that reproducibly fired in a sequential manner, with more D1R and D2R neurons fired during the lever-pushing period and intertrial intervals (ITIs), respectively. This sequential firing pattern was specifically associated with the learned motor behavior, because it changed markedly when the trained mice performed other cued motor tasks. Selective chemogenetic silencing of D1R and D2R neurons impaired the initiation of learned motor action and suppression of erroneous lever pushing during ITIs, respectively. Thus, motor learning involves reorganization of DLS neuronal activity, forming stable D1R and D2R neuronal ensembles that fired sequentially to regulate different aspects of the learned behavior.

Design of Evaluation Areas Based on Type of Mobile-Based Virtual Reality Training Content

In the field of technology education, virtual reality (VR) training has received significant attention in terms of its efficacy in use. Given its many advantages, there is a specific need to emphasize concrete measures for the implementation of VR training in the field of tech education. VR training based on mobile environments has been touted as a means of not only enhancing presence, flow, and learning authenticity, but also of minimizing spatial and temporal constraints. The present study has developed an evaluation tool for VR training contents, including those based on mobile environments. After categorizing VR training contents in the field of tech education into structure comprehension type, procedure learning type, and equipment experiment type contents, we constructed items for each evaluation area. The considered areas included learning, media, and content quality. By conducting Delphi surveys with a panel of experts, we confirmed that the derived evaluation items differed in number across different types of content. Under the learning area, satisfaction was found to be adequate for all content types. Items such as flow, interactivity, and learning effects were found to be adequate for procedure learning and equipment experiment type contents. The media area indicated marked variability in item adequacy depending on the content type. Usability was found to be adequate only for procedure learning type content. For equipment experiment type content, items such as presence, usability, and manipulability were all found to be adequate. All evaluation items under the content design area were found to be adequate across all content types. Thus, regardless of the type of content, it is necessary to fulfil the basic elements within the content design area in order to establish the efficacy of VR training as educational content in the field of tech education.