Red Mud from the Aluminium Industry: Production, Characteristics, and Alternative Applications in Construction Materials—A Review

About 120 million tons of red mud is produced worldwide each year. Due to its high basicity and potential leaching, its storage is a critical environmental problem. This material is typically stored in dams, which demands prior care of the disposal area and includes monitoring and maintenance throughout its useful life. Consequently, it is crucial to figure out an industrial solution able to consumes large volumes of this material. At this moment, there are several studies, the majority in metallurgical procedures, building materials, and in the chemical industry, discussing how to reuse red mud. This paper provides a review of the aluminium process, including metal importance, its global production, and the environmental impact due to its manufacture process. It presents a review of the potential application of red mud showing its overall generation, some relevant characterisation results collected from the literature, and its utilisation in diverse areas of engineering. The study aimed to highlight applications where red mud characteristics may be favourable.

Correlation among the oxide ion polarizability, optical basicity and interaction parameter in Gd3+ ions doped oxyhalide borate glasses

A borate glasses doped with rare earth Gd3+ ion in the system [6OB2O3 + 30 L12O + x Gd2O3 + (10-x) BiCl3] is prepared by the conventional melt quenching method and their optical properties have been studied. The oxide ion polarizability parameter is calculating by using refractive index of glass materials, which is obtained from UV-Vis spectra. The borate glasses are known to possess high oxide ion polarizability, high refractive index, high basicity and low interaction parameter values. In this present study, theoretical calculation of basicity and interaction parameter, using oxide ion polarization, of the glass network has been addressed. A good linear correlation between the interaction parameter and basicity is observed.

Factors Influencing Dephosphorization of Low Carbon Steel in Converter

A 300-metric ton converter in a steel plant in China was studied. The influence of factors such as slag composition and temperature in the smelting process on the dephosphorization effect was statistically analyzed. The dephosphorization ability of slag increased firstly and then decreased with the increase of temperature, basicity and FeO content. Low-temperature, high-basicity and high-oxidizing slag are thermodynamically beneficial to promote the dephosphorization reaction, but the basicity is higher than 4.0, and the temperature is higher than 1640 °C are not conducive to the slag to obtain better fluidity. At the same time, too high FeO content will increase the activity coefficient of P2O5, thereby increasing its activity, which is not conducive to the progress of the dephosphorization reaction. As the end point content of carbon decreases, the oxygen content increases and the phosphorus content decreases. A very low carbon content is not conducive to metal yield and temperature control.

Study on Sintering Characteristics of Ultra-Poor Vanadium-Titanium Magnetite

Artificial rich ore for blast furnace use can be produced by sintering ultra-poor vanadium-titanium magnetite (PVTM) with a high-grade iron concentrate. Here, acid (R = 0.33, 0.50), self-fluxing (R = 1.10), and high-basicity (R = 2.60) PVTM sinters were produced in a sinter pot. Their performances were determined using the comprehensive index. The microstructures of the PVTM sinter were observed by metallographic microscope and scanning electron microscopy equipped with an energy dispersion spectrum (SEM-EDS). The results suggest that the acid PVTM sinter had a low flame front speed, low productivity, an uneven size distribution, and poor softening properties. It did have a high tumble index (TI) and low-temperature reduction disintegration index (RDI). The self-fluxing PVTM sinter had the worst performance (TI, RDI, reducibility index (RI)), while the high-basicity PVTM sinter had the highest flame front speed, highest productivity, a reasonable size distribution, excellent softening properties, and satisfactory TI and RDI values. The main consolidation form of the acid sinter was crystal stock, the main bonding phase of the self-fluxing sinter was silicate, and the main bonding phase of the high-basicity sinter was silico-ferrite of calcium and aluminum (SFCA). The comprehensive index values (from high to low) were the high-basicity (R = 2.60), acid (R = 0.50), natural acid (R = 0.33), and self-fluxing (R = 1.10) PVTM sinters. When the production capacity of the acid pellet was in shortage, the acid PVTM sinter (R = 0.50) could be produced by the surplus from the sinter plant. This replaced a part of the acid pellet and the burden structural model of the blast furnace smelting vanadium so the titanium burden could adopt a ‘high-basicity PVTM sinter + acid V-Ti pellet + acid (R = 0.50) PVTM sinter’.

Mechanism-Based Design of Quinoline Potassium Acyltrifluoroborates (KATs) for Rapid Amide-Forming Ligations at Physiological pH

<div><div><div><p>Potassium acyltrifluoroborates (KATs) undergo chemoselective amide-forming ligations with hydroxylamines. Under aqueous, acidic conditions these ligations can proceed rapidly, with rate constants of ~20 M-1 s-1. The requirement for lower pH to obtain the fastest rates, however, limits their use with certain biomolecules and precludes in vivo applications. By mechanistic investigations into the KAT ligation, including kinetic studies, X-ray crystallography, and DFT calculations, we have identified a key role for a proton in accelerating the ligation. We applied this knowledge to the design and synthesis of 8-quinolyl acyltrifluoroborates, a new class of KATs that ligates with hydroxylamines at pH 7.4 with rate constants >4 M-1 s-1. We trace the enhanced rate at physiological pH to unexpectedly high basicity of the 8-quinoline-KATs, which leads to their protonation even under neutral conditions. This proton assists the formation of the key tetrahedral intermediate and activates the leaving groups on the hydroxylamine towards a concerted 1,2-BF3shift that leads to the amide product. We demonstrate that the fast ligations at pH 7.4 can be carried out with a protein substrate at micromolar concentrations.</p></div></div></div>

Mechanism-Based Design of Quinoline Potassium Acyltrifluoroborates (KATs) for Rapid Amide-Forming Ligations at Physiological pH

<div><div><div><p>Potassium acyltrifluoroborates (KATs) undergo chemoselective amide-forming ligations with hydroxylamines. Under aqueous, acidic conditions these ligations can proceed rapidly, with rate constants of ~20 M-1 s-1. The requirement for lower pH to obtain the fastest rates, however, limits their use with certain biomolecules and precludes in vivo applications. By mechanistic investigations into the KAT ligation, including kinetic studies, X-ray crystallography, and DFT calculations, we have identified a key role for a proton in accelerating the ligation. We applied this knowledge to the design and synthesis of 8-quinolyl acyltrifluoroborates, a new class of KATs that ligates with hydroxylamines at pH 7.4 with rate constants >4 M-1 s-1. We trace the enhanced rate at physiological pH to unexpectedly high basicity of the 8-quinoline-KATs, which leads to their protonation even under neutral conditions. This proton assists the formation of the key tetrahedral intermediate and activates the leaving groups on the hydroxylamine towards a concerted 1,2-BF3shift that leads to the amide product. We demonstrate that the fast ligations at pH 7.4 can be carried out with a protein substrate at micromolar concentrations.</p></div></div></div>

Insights into Elution of Anion Exchange Cartridges: Opening the Path towards Aliphatic 18F-Radiolabeling of Base-Sensitive Tracers

Aliphatic nucleophilic substitution (S_N2) with [¹⁸F]fluoride is the most widely applied method to prepare ¹⁸F-labeled positron emission tomography (PET) tracers. Strongly basic conditions commonly used during ¹⁸F-labeling procedures inherently limit or prohibit labeling of base-sensitive scaffolds. The high basicity stems from the tradition to trap [¹⁸F]fluoride on anion exchange cartridges and elute it afterwards with basic anions. This sequence is used to facilitate the transfer of [¹⁸F]fluoride from an aqueous to an aprotic organic, polar reaction medium, which is beneficial for S_N2 reactions. Furthermore, this sequence also removes cationic radioactive contaminations from cyclotron-irradiated [¹⁸O]water from which [¹⁸F]fluoride is produced. In this study, we developed an efficient elution procedure resulting in low basicity that permits S_N2 ¹⁸F-labeling of base-sensitive scaffolds. Extensive screening of trapping and elution conditions (>1000 experiments) and studying their influence on the radiochemical yield (RCY) allowed us to identify a suitable procedure for this. Four PET tracers and three synthons could be radiolabeled in substantially higher RCYs (up to 2.5-fold), even from lower precursor amounts, using this procedure. Encouraged by these results, we applied our low basicity method to the radiolabeling of highly base-sensitive tetrazines, which cannot be labeled using state-of-art direct aliphatic ¹⁸F-labeling procedures. Labeling succeeded in RCYs of up to 20%. We believe that our findings facilitate PET tracer development by opening the path towards simple and direct S_N2 ¹⁸F-fluorination of base-sensitive substrates.

Insights into Elution of Anion Exchange Cartridges: Opening the Path towards Aliphatic 18F-Radiolabeling of Base-Sensitive Tracers

Aliphatic nucleophilic substitution (S_N2) with [¹⁸F]fluoride is the most widely applied method to prepare ¹⁸F-labeled positron emission tomography (PET) tracers. Strongly basic conditions commonly used during ¹⁸F-labeling procedures inherently limit or prohibit labeling of base-sensitive scaffolds. The high basicity stems from the tradition to trap [¹⁸F]fluoride on anion exchange cartridges and elute it afterwards with basic anions. This sequence is used to facilitate the transfer of [¹⁸F]fluoride from an aqueous to an aprotic organic, polar reaction medium, which is beneficial for S_N2 reactions. Furthermore, this sequence also removes cationic radioactive contaminations from cyclotron-irradiated [¹⁸O]water from which [¹⁸F]fluoride is produced. In this study, we developed an efficient elution procedure resulting in low basicity that permits S_N2 ¹⁸F-labeling of base-sensitive scaffolds. Extensive screening of trapping and elution conditions (>1000 experiments) and studying their influence on the radiochemical yield (RCY) allowed us to identify a suitable procedure for this. Four PET tracers and three synthons could be radiolabeled in substantially higher RCYs (up to 2.5-fold), even from lower precursor amounts, using this procedure. Encouraged by these results, we applied our low basicity method to the radiolabeling of highly base-sensitive tetrazines, which cannot be labeled using state-of-art direct aliphatic ¹⁸F-labeling procedures. Labeling succeeded in RCYs of up to 20%. We believe that our findings facilitate PET tracer development by opening the path towards simple and direct S_N2 ¹⁸F-fluorination of base-sensitive substrates.