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2021 ◽  
Vol 8 ◽  
Author(s):  
Kanchana Leerunyakul ◽  
Kallapan Pakornphadungsit ◽  
Poonkiat Suchonwanit

Vaccination is one of the cornerstones in the efforts towards ending the coronavirus disease 2019 (COVID-19) pandemic. However, several adverse effects of COVID-19 vaccination have been identified. Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. Here, we described a case of PR-like eruption that developed 14 days after Oxford/AstraZeneca vaccination in a 52-year-old Thai woman with glioblastoma. Treatment with topical 0.1% triamcinolone acetonide twice per day showed partial response after seven days. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations.


Litera ◽  
2021 ◽  
pp. 37-44
Author(s):  
Kseniya Borisovna Volkova

The object of this research is the evolution of female image in the works of King Vajiravudh of Siam, who is considered the father of modern Thai literature. The subject of this research is the portraits of heroines in the original Thai-language works of the monarch, both dramatic and epic, which allow us tracing the artistic transformations of female images. The historical and biographical methods reveal the status of women in the new Thai society of the early XX century and how it affect the author’s views. The problematic of the “feminine” was associated with the author’s pursuit of ideal of Thai woman from ethical perspective. This is the first research on the topic within Thai or foreign historiography. The female images, the role of women in society and fate of the nation is the pervasive theme in all works by King Vajiravudh. The author disrupts the traditional canon and depicts a new woman, who claims her rights to the freedom of choice despite the patriarchal principles. At the same time, the entire gallery of female images is an attempt to find compromise between the progress and traditional values, to create the ideal of Thai woman, which could find realization in real life.


2021 ◽  
Vol 104 (7) ◽  
pp. 1214-1217

The authors report a case of a 32-year-old Thai woman with a COVID-19 infection that presented with urticaria and angioedema with a pityriasis rosea (PR)-like rash at a private hospital in Thailand. She presented at the hospital with bloody nasal discharge and diarrhea but without fever, myalgia, or any respiratory symptoms. She complained of angioedema and PR-like lesions on the third day of the treatment. Urticarial rash appeared intermittently for four weeks after all medications were discontinued, during which the patient had no fever, no respiratory symptoms, or any other symptoms. However, the RT-PCR results for COVID-19 RNA were positive during the time that the urticarial symptoms persisted. The COVID-19 RNA became negative on the fourth day after the last urticarial episode. Urticarial rash may be a clue that the inflammatory process is activated by COVID-19 virus after the treatment is completed. Keywords: Cutaneous; Pityriasis rosea; Angioedema; Urticaria; COVID-19


2021 ◽  
Vol 132 ◽  
pp. S345-S346
Author(s):  
Pongtawat Lertwilaiwittaya ◽  
Chanin Limwongse ◽  
Manop Pithukpakorn ◽  
Varalak Srinonprasert

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Chaisith Sivakorn ◽  
Polrat Wilairatana ◽  
Srivicha Krudsood ◽  
Marcus J. Schultz ◽  
Tachpon Techarang ◽  
...  

AbstractImpaired autonomic control of postural homeostasis resulting in orthostatic hypotension has been described in falciparum malaria. However, severe orthostatic intolerance in Plasmodium vivax has been rarely reported. A case of non-immune previously healthy Thai woman presenting with P. vivax infection with well-documented orthostatic hypotension is described. In addition to oral chloroquine and intravenous artesunate, the patient was treated with fluid resuscitation and norepinephrine. During hospitalization, her haemodynamic profile revealed orthostatic hypotension persisting for another three days after microscopic and polymerase chain reaction confirmed parasite clearance. Potential causes are discussed.


2020 ◽  
Vol 14 (3) ◽  
pp. 702-706
Author(s):  
Tanyaporn Chantarojanasiri ◽  
Arunluk Buranathawornsom ◽  
Apichet Sirinawasatien

Acanthosis nigricans with tripe palms is one of the skin manifestations of systemic conditions, as well as internal malignancy. There have been reports of this paraneoplastic condition’s association with orocutaneous papillomatosis, but investigations into its relationship with diffuse esophageal papillomatosis are scarce. We report a case of acanthosis nigricans with tripe palms that was associated with diffuse esophageal squamous papillomatosis. A 40-year-old Thai woman with underlying systemic lupus erythematosus and secondary Sjögren’s syndrome, who was recently diagnosed with acanthosis nigricans and tripe palms was investigated for occult gastrointestinal malignancy. An upper GI endoscopy revealed diffuse squamous papilloma along the entire esophagus and lower GI endoscopy revealed one pedunculated hyperplastic polyp 1 cm in size at the sigmoid colon. Long-term follow-up is needed to reassure these coexisting conditions belonging to benign systemic diseases without hidden malignancy.


2020 ◽  
Author(s):  
Chaisith Sivakorn ◽  
Polrat Wilairatana ◽  
Srivicha Krudsood ◽  
Marcus J. Schultz ◽  
Tachpon Techarang ◽  
...  

Abstract Impaired autonomic control of postural homeostasis resulting in orthostatic hypotension has been described in falciparum malaria. However, severe orthostatic intolerance in Plasmodium vivax has not been previously reported. We describe a non-immune previously healthy Thai woman presenting with Plasmodium vivax infection with well-documented orthostatic hypotension. In addition to oral chloroquine and intravenous artesunate, the patient was treated with fluid resuscitation and norepinephrine. During hospitalization, her hemodynamic profile revealed orthostatic hypotension persisting for another three days after microscopic and polymerase chain reaction confirmed parasite clearance. Potential causes are discussed.


2020 ◽  
Vol 63 (9) ◽  
pp. 103982
Author(s):  
Chureerat Phokaew ◽  
Rekwan Sittiwangkul ◽  
Kanya Suphapeetiporn ◽  
Vorasuk Shotelersuk
Keyword(s):  

2020 ◽  
Vol 6 (3) ◽  
pp. 1
Author(s):  
Wattana Insiripong ◽  
Somchai Insiripong

Either dengue fever or diabetic ketoacidosis can cause the high hemoglobin concentration due to intravascular volume loss. When both entities were found together as in our case, the hemoglobin concentration could access the strikingly high level until either of them could not contribute it. She was a Thai woman with 46 years of age presenting with fever, fatigue and severe sore throat for a few days. The physical examination showed she had mild dyspnea and oral thrush, the temperature was 36.4 degree Celsius, and her pulse rate was 102/min. Her blood tests showed: Hb 18.3 g%, WBC 9,850/mm3, atypical lymphocyte 10%, platelet 16,000/mm3, MCV 89.2 fl, Dengue NS1 antigen-positive, dengue IgG-positive, IgM-weakly positive, KOH preparation of curd from buccal mucosa-positive for budding yeasts and pseudo-hyphae, blood sugar 442 mg%, triglyceride 578 mg%, Na 122.8 mEq/L, K 6.28 mEq/L, Cl 90.6 mEq/L, CO2 9.2 mEq/L, blood ketone 53.6 mmol/L, lactate 4.5 mmol/L, pH 7.257, pCO2 27.4 mmHg, HCO3 11.9 mmo/L, BUN 22.9 mg%, creatinine 0.64 mg%, AST 375 U/L, ALT 224 U/L, alkaline phosphatase 151 U/L. She was diagnosed as having diabetes with diabetic ketoacidosis, dengue fever and polycythemia. She was immediately treated with intravenous fluid therapy to correct the metabolic acidosis, electrolyte imbalance and dehydration, insulin for hyperglycemia, clotrimazole for oral thrush and platelet transfusion. Her high hemoglobin level was dramatically lowered until became normal within one day of therapy whereas she also recovered from DKA although the platelet was progressively lowered every day. It suggested that transient polycythemia was solely contributed by DKA that was triggered by dengue fever hence DKA from dengue fever should be added in the list of unusual causes of transient polycythemia.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Thanyarak Wongkamhla ◽  
Piriyaporn Chongtrakool ◽  
Anupop Jitmuang

Abstract Background The incidence of Taralomyces marneffei infection in HIV-infected individuals has been decreasing, whereas its rate is rising among non-HIV immunodeficient persons, particularly patients with anti-interferon-gamma autoantibodies. T. marneffei usually causes invasive and disseminated infections, including fungemia. T. marneffei oro-pharyngo-laryngitis is an unusual manifestation of talaromycosis. Case presentation A 52-year-old Thai woman had been diagnosed anti-IFNɣ autoantibodies for 4 years. She had a sore throat, odynophagia, and hoarseness for 3 weeks. She also had febrile symptoms and lost 5 kg in weight. Physical examination revealed marked swelling and hyperemia of both sides of the tonsils, the uvula and palatal arches including a swelling of the epiglottis, and arytenoid. The right tonsillar biopsy exhibited a few intracellular oval and elongated yeast-like organisms with some central transverse septum seen, which subsequently grew a few colonies of T. marneffei on fungal cultures. The patient received amphotericin B deoxycholate 45 mg/dayfor 1 weeks, followed by oral itraconazole 400 mg/day for several months. Her symptoms completely resolved without complication. Conclusion In patients with anti-IFN-ɣ autoantibodies, T. marneffei can rarely cause a local infection involving oropharynx and larynx. Fungal culture and pathological examination are warranted for diagnosis T. marneffei oro-pharyngo-laryngitis. This condition requires a long term antifungal therapy.


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