splenic lymphoma
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2022 ◽  
Vol 17 (3) ◽  
pp. 467-472
Author(s):  
Divina D'Auria ◽  
Dolores Ferrara ◽  
Gioconda Argenziano ◽  
Domenico Noviello ◽  
Anna Marcella Giugliano ◽  
...  

2021 ◽  
Vol 29 (1) ◽  
pp. 130-131
Author(s):  
Victor E. Nava

Malignant lymphoproliferative disorders in the spleen may be primary (usually designated as splenic lymphoma) or secondary (due to progression of nodal or extra nodal lymphoid neoplasms) and represent an underestimated cause of splenomegaly, partially due to the decreasing frequency of splenectomy in our era of personalized molecular medicine [...]


2021 ◽  
Vol 2 (6) ◽  
pp. 6-9
Author(s):  
Leonid I. Dvoretsky ◽  
◽  
Oleg E. Lutsevich ◽  
Vasilii V. Filippov ◽  
Sergei S. Golubev ◽  
...  

The case of primary splenic lymphoma, the uncommon type of non-Hodgkin lymphoma presenting with prominent splenomegaly, is reported. The disease is characterized by long asymptomatic stage and splenic abscess found during splenectomy.


2021 ◽  
Author(s):  
Feryel Ksontini Letaief ◽  
Issaad Nefzi ◽  
salim khrouf ◽  
Sonia ouali ◽  
Asma Zidi ◽  
...  

Abstract PurposeGastrosplenic fistula (GSF) is a rare and potentially fatal complication of various diseases, of which lymphoma is the most common cause. We aim through our work to relate two cases of GSF and to review literature. Methods We reviewed two cases treated in our department of GSF and made a research in Pubmed using the keywords “Gastrosplenic fistula” and “Splenic lymphoma”.Results GSF is a rare condition that can occur spontaneously or after initiation of chemotherapy. It arises from the rapid growth of tumour and invasion of surrounding organs. Diagnosis may be difficult to make and confused with splenic abscess. Treatment modalities include surgical resection, chemotherapy or a combination of both. Here we report two cases of GSF due to diffuse large B cell lymphoma patients. The first case is of a 54-year-old woman with a spontaneous fistula in the stomach. The second one is of a 48 year-old- male patient presenting a fistula after chemotherapy. Both patients died after surgery. ConclusionGSF is a rare but dangerous condition in which surgery is currently the preferred treatment.


Author(s):  
Fabio Carboni ◽  
Renato Covello ◽  
Mario Valle

2021 ◽  
Vol 7 (1) ◽  
pp. 20-22
Author(s):  
Robert A. Ries ◽  
Christina L. Jacovides ◽  
Jennifer Rashti ◽  
Jerald Z. Gong ◽  
Charles J. Yeo

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Melissa Lumish ◽  
Lorenzo Falchi ◽  
Brandon S. Imber ◽  
Michael Scordo ◽  
Gottfried von Keudell ◽  
...  

AbstractMature B cell neoplasms, previously indolent non-Hodgkin lymphomas (iNHLs), are a heterogeneous group of malignancies sharing similar disease courses and treatment paradigms. Most patients with iNHL have an excellent prognosis, and in many, treatment can be deferred for years. However, some patients will have an accelerated course and may experience transformation into aggressive lymphomas. In this review, we focus on management concepts shared across iNHLs, as well as histology-specific strategies. We address open questions in the field, including the influence of genomics and molecular pathway alterations on treatment decisions. In addition, we review the management of uncommon clinical entities including nodular lymphocyte-predominant Hodgkin lymphoma, hairy cell leukemia, splenic lymphoma and primary lymphoma of extranodal sites. Finally, we include a perspective on novel targeted therapies, antibodies, antibody–drug conjugates, bispecific T cell engagers and chimeric antigen receptor T cell therapy.


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