timely review
Recently Published Documents


TOTAL DOCUMENTS

97
(FIVE YEARS 33)

H-INDEX

14
(FIVE YEARS 3)

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4543
Author(s):  
Rocco Caliandro ◽  
Astrid A. Streng ◽  
Linda W. M. van Kerkhof ◽  
Gijsbertus T. J. van der Horst ◽  
Inês Chaves

The term social jetlag is used to describe the discrepancy between biological time, determined by our internal body clock, and social times, mainly dictated by social obligations such as school or work. In industrialized countries, two-thirds of the studying/working population experiences social jetlag, often for several years. Described for the first time in 2006, a considerable effort has been put into understanding the effects of social jetlag on human physiopathology, yet our understanding of this phenomenon is still very limited. Due to its high prevalence, social jetlag is becoming a primary concern for public health. This review summarizes current knowledge regarding social jetlag, social jetlag associated behavior (e.g., unhealthy eating patterns) and related risks for human health.


Author(s):  
Hirofumi Sakuma ◽  
Izumi Ojima ◽  
Motoichi Ohtsu ◽  
Tadashi Kawazoe

Abstract On the very recent advancement of dressed photon studies A timely review of the emerging new phase of dressed photon (DP) studies, not yet prevailing in the global nanophotonic society, is given in contradistinction to its preceding incipient phase. A new theory on DPs crucially depends on a couple of important elements, namely, the knowledge on quantum field theory (QFT) having infinite degrees of freedom, notably on the micro-macro duality (MMD) theory developed by Ojima, and a newly proposed Clebsch dual (CD) electromagnetic field as a specific implementation of MMD theory. The main aim of the first part of this article after the introduction, the section of “In search of refinement of the theoretical models”, is twofold: to explain plainly, without resorting to mathematical equations, the essence of the highly mathematical contents of MMD theory, which clarifies a problematic aspect of the Schrödinger’s cat thought experiment, and to explain the physical meanings of the CD field. Preliminary study on the existence of DP light with spin zero In the section of “Observed “photon cluster” and light field with spin zero”, we briefly report a new intriguing experimental discovery implying the existence of propagating particle-like “quantum DP light” together with a conjecture on its possible theoretical explanation. A perspective on a variety of possible research directions for DPs is then briefly mentioned in mentioned in the final section.


Plants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2179
Author(s):  
Vimalraj Mani ◽  
Soyoung Park ◽  
Jin A Kim ◽  
Soo In Lee ◽  
Kijong Lee

Terpenoids represent one of the high-value groups of specialized metabolites with vast structural diversity. They exhibit versatile human benefits and have been successfully exploited in several sectors of day-to-day life applications, including cosmetics, foods, and pharmaceuticals. Historically, the potential use of terpenoids is challenging, and highly hampered by their bioavailability in their natural sources. Significant progress has been made in recent years to overcome such challenges by advancing the heterologous production platforms of hosts and metabolic engineering technologies. Herein, we summarize the latest developments associated with analytical platforms, metabolic engineering, and synthetic biology, with a focus on two terpenoid classes: monoterpenoids and sesquiterpenoids. Accumulated data showed that subcellular localization of both the precursor pool and the introduced enzymes were the crucial factors for increasing the production of targeted terpenoids in plants. We believe this timely review provides a glimpse of current state-of-the-art techniques/methodologies related to terpenoid engineering that would facilitate further improvements in terpenoids research.


Author(s):  
Ivan Ivanov ◽  
Sebastián López Castellanos ◽  
Severo Balasbas ◽  
Lado Otrin ◽  
Nika Marušič ◽  
...  

The bottom-up approach in synthetic biology aims to create molecular ensembles that reproduce the organization and functions of living organisms and strives to integrate them in a modular and hierarchical fashion toward the basic unit of life—the cell—and beyond. This young field stands on the shoulders of fundamental research in molecular biology and biochemistry, next to synthetic chemistry, and, augmented by an engineering framework, has seen tremendous progress in recent years thanks to multiple technological and scientific advancements. In this timely review of the research over the past decade, we focus on three essential features of living cells: the ability to self-reproduce via recursive cycles of growth and division, the harnessing of energy to drive cellular processes, and the assembly of metabolic pathways. In addition, we cover the increasing efforts to establish multicellular systems via different communication strategies and critically evaluate the potential applications.


Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2892
Author(s):  
Manuel Jiménez-Estrada ◽  
Maira Huerta-Reyes ◽  
Rosario Tavera-Hernández ◽  
J. Javier Alvarado-Sansininea ◽  
Ana Berenice Alvarez

Diabetes mellitus (DM) is cited as a serious worldwide health problem that occupies second place in causes of annual mortality in Mexico. Among Mexican flora, nearly 300 plant species have been employed as hypoglycemic in popular use. Thus, their study entertains great relevance In this context, this work contributes a clear and timely review of the plant species utilized in Traditional Mexican Medicine and experimental biological models in which not only have the hypoglycemic properties of the extracts and the isolated compounds been considered, but also the anti-inflammatory and antioxidant properties, taking into account an integral focus based on the complex mechanisms involved in the pathogenesis and physiopathology of DM. Among the species reviewed, we highlight Psacalium decompositum (Asteraceae), due to the potent hypoglycemic, anti-inflammatory, and antioxidant activity of the sesquiterpenes identified as majority compounds isolated from the root, such as cacalol and cacalone that also possess the capacity of increasing insulin levels. In this manner, the present manuscript attempts to contribute necessary information for the future study of bioactive molecules that are useful in the treatment of DM, as well as also being a contribution to the knowledge and diffusion of Mexican Traditional Medicine.


2021 ◽  
Author(s):  
Carol Callaway Dee ◽  
Ayalew Lulseged ◽  
Tianming Zhang

We investigate if Big 4 firms are asymmetrically more effective than non-Big 4 firms in monitoring income-increasing vs. income-decreasing quarterly earnings management. We also study the Securities and Exchange Commission's (SEC) 2000 requirement that audit firm reviews of quarterly financial statements be completed prior to their filing with the SEC ("timely reviews"). We find Big 4 firms are more effective than non-Big 4 firms in curbing income-increasing earnings management around seasoned equity offerings (SEOs), but not income-decreasing earnings management around open market repurchases (OMRs). In the post-2000 period, after the SEC's mandate for timely reviews began, we find income-increasing earnings management around SEOs declined significantly, and this decline is primarily driven by the clients of Big 4 firms. We provide evidence that timely quarterly reviews improve earnings quality, especially when companies have incentives to engage in income-increasing accruals and are reviewed by Big 4 firms.


2021 ◽  
Vol 59 (1) ◽  
Author(s):  
Mariia Tepliuk ◽  
Olexandr Shapran

The article proves that at the present time when countries are joining forces to recover, prosper and overcome the global economic and financial crisis associated with COVID- 19, scientists and practitioners are focusing on updating the development of innovative entrepreneurship. It will lead to economic recovery, job creation, and in the long run, it will lead to a reduction in poverty. It will lead to the solution of crucial social problems. Ensuring the increase in sufficient activity of economic entities in presentday conditions of operation requires a timely review of the needs of the external and internal environment and the search for ways to meet them. The purpose of the article is to identify the key parameters of the activation of innovative development in the context of the DEST World


2021 ◽  
Vol 14 (3) ◽  
pp. 1
Author(s):  
Qinxu Jiang ◽  
Shimin Soon ◽  
Yuandong Li

In an increasingly interconnected world, intercultural competency has become an essential skill for many. It is important for students to learn this skill, but are teachers equipped to instil such knowledge not just adequately, but also objectively and without prejudice? In light of the recent explosion in telecommunications-assisted teaching and learning, this is a timely review on the use of online technology as cognitive tools for enhancing teachers’ intercultural competency skills. Though various online platforms for learning and sharing have been developed for and used by students over the years, less attention has been given to teachers’ needs; only five well-documented projects pertaining to the upskilling of intercultural competence were found. We focus on these five projects and draw from them best practices, platforms and methods of potential and other insights, which would provide the best benefits in meeting the professional development needs of teachers.


Sign in / Sign up

Export Citation Format

Share Document