MDCT Imaging of Non-Traumatic Thoracic Aortic Emergencies and Its Impact on Diagnosis and Management—A Reappraisal

Non-traumatic thoracic aorta emergencies are associated with significant morbidity and mortality. Diseases of the intimomedial layers (aortic dissection and variants) have been grouped under the common term of acute aortic syndrome because they are life-threatening conditions clinically indistinguishable on presentation. Patients with aortic dissection may present with a wide variety of symptoms secondary to the pattern of dissection and end organ malperfusion. Other conditions may be seen in patients with acute symptoms, including ruptured and unstable thoracic aortic aneurysm, iatrogenic or infective pseudoaneurysms, aortic fistula, acute aortic thrombus/occlusive disease, and vasculitis. Imaging plays a pivotal role in the patient’s management and care. In the emergency room, chest X-ray is the initial imaging test offering a screening evaluation for alternative common differential diagnoses and a preliminary assessment of the mediastinal dimensions. State-of-the-art multidetector computed tomography angiography (CTA) provides a widely available, rapid, replicable, noninvasive diagnostic imaging with sensitivity approaching 100%. It is an impressive tool in decision-making process with a deep impact on treatment including endovascular or open surgical or conservative treatment. Radiologists must be familiar with the spectrum of these entities to help triage patients appropriately and efficiently. Understanding the imaging findings and proper measurement techniques allow the radiologist to suggest the most appropriate next management step.

A REVIEW ON UNDERSTANDING OF SCOLIOSIS AND ITS AYURVEDIC ASPECTS

The spinal curvatures are important for balancing the body and it help us to stand upright. If any one of the curves become too large or small, our posture may appear abnormal. There are three main types of spinal curvature disor- ders, viz: scoliosis, kyphosis and lordosis. Among these, scoliosis is the common one. Scoliosis is a lateral curvature of the spine that occurs most often during the growth spurt just before puberty. In 80% of scoliosis patients, the cause is unknown. In most of the cases the curve is mild, but in some children the curve continues to worsen as the child grows. Children who have mild scoliosis need to be monitored closely. In such cases, no treatment is usually necessary. Some of them will need to wear a brace. The ultimate treatment for a progressive curve in children is surgery. While going through Ayurveda literature, we see the word Kubja, and is a common term used by Acharyas to describe a hump like appearance. This article is intended to review scoliosis, its classification, symptoms, diag- nosis and treatment and its Ayurvedic aspects. Keywords: Scoliosis, Brace, Kubja

Legal status and characteristics of a digital human

The article outlines the path that humanity is developing from Homo sapiens to digital human being in three main vectors. The latest high-tech devices have been proven to provide a tight interactive connection with the user, thus gradually becoming an integral part of the biological body and human consciousness, a kind of organs or chains for transmitting nerve signals. The possibility of combining carbon technology (human) with silicon technology (artificial intelligence, implants, robotics) creates a powerful new challenge for legal doctrine, one of the main tasks of which is to describe the legal characteristics of digital human being, determine his or her legal status in the law system. To generalize the concepts of transhuman and posthuman, which operates on transhumanism, the author proposes to use the common term of digital human being. The necessity of directing state regulation to limit or prevent the antisocial use of improved physical and cognitive properties by digital human being is argued. The possibility of quantum immortality is considered. It has been suggested that new rights, responsibilities, and freedoms may emerge that now exist only in theory or even beyond imagination and discussion. They can become the subject of supernatural law as the successor of natural law. The possibility of the transition of the decision-making process from a digital human being to artificial intelligence in its implant, when the brain will continue to receive signals that will form the illusion of free will, is analysed. It is proved that a digital human being must be recognized as a special persona of legal relations.

Social-emotional Competencies in Peruvian Educational Institutions

The socioemotional competencies contribute to the integral formation of the student as it unites the cognitive with the emotional; at the criterion of this study, two stages were considered to be approached in the school: the first one promoted an adequate coexistence of all the actors of the educational community, avoiding the situation of violence: the second stage will have to do with the effects produced during the health emergency by the COVID- 19. The main purpose of this study was to inquire about the academic literature on the subject of socioemotional competence in the context of Peruvian educational institutions. The method employed was a qualitative descriptive literature review. The results allowed exploring the topic from academic and documentary contributions. It was concluded that there is no consensus on a common term for socioemotional competencies; however, there is no doubt that the impulse given in educational institutions contributes to the integral formation of the student.

Globalizing Higher Education and its Impact on Indian Expat Students (A Case Study of Indian Expat Students Living in UAE)

Education is the backbone of a progressive society as it is clear from the statement of Thomas Jefferson “educate the masses” as he believed that in order to make changes in a society, the whole masses should be educated. The term ‘education’ is a popular and common term used by everybody but understood by very few in its right perspective. In educational text books it is defined as a purposive, conscious or unconscious, psychological, sociological, scientific and philosophical process that brings about development of the individual to fullest extent and also the maximum development of society in such a way that both enjoy happiness and prosperity. Despite the existence of infrastructural facilities, economic status and availability of various educational courses, the attitude towards higher education and learning is not found to be positive among the Indian expat students. The ultimate objective of this study is to find out the factors that influence the attitude of the students towards higher education and recommend sufficient measures to improve it.

The Effect Of Particle Size On The Characterization Of Activated Carbon From Tropical Black Bamboo (Gigantochloa Atroviolacea)

Activated carbon also known as activated charcoal is a common term for carbon materials, which comprises charcoal. Activated carbon has a good adsorption capacity against gases and pollutants in liquids because of its wide surface. The material used in this research was tropical black bamboo, with the variation of particle size -10+20 mesh, -20+40 mesh, -40+60 mesh and -60+80 mesh. There are 2 processes to produce activated carbon, i.e. carbonation and activation. In this research, the carbonation is set at 380°C in 1 hour. Then, each size of carbon was activated by H3PO4 9.8% along 24 hours. The analysis conducted were moisture content, ash content, iodine number, and functional group analysis using Fourier Transform Infrared Spectroscopy (FTIR). The smaller particle size, the more pores will be produced and it caused the surface area higher. The results showed that variation of particle size had effect on the characterization and quality of activated carbon, where moisture content is between 10.60 to 4.05%, ash content is 1% to 0.2% and iodine adsorption is between 710 mg/g to 900 mg/g. In FTIR analysis, it showed that all of the samples had O-H, C=C, and C-O functional group.

Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring

Liquid biopsy is a common term referring to circulating tumor cells and other biomarkers, such as circulating tumor DNA (ctDNA) or extracellular vesicles. Liquid biopsy presents a range of clinical advantages, such as the low invasiveness of the blood sample collection and continuous control of the tumor progression. In addition, this approach enables the mechanisms of drug resistance to be determined in various methods of cancer treatment, including immunotherapy. However, in the case of melanoma, the application of liquid biopsy in patient stratification and therapy needs further investigation. This review attempts to collect all of the relevant and recent information about circulating melanoma cells (CMCs) related to the context of malignant melanoma and immunotherapy. Furthermore, the biology of liquid biopsy analytes, including CMCs, ctDNA, mRNA and exosomes, as well as techniques for their detection and isolation, are also described. The available data support the notion that thoughtful selection of biomarkers and technologies for their detection can contribute to the development of precision medicine by increasing the efficacy of cancer diagnostics and treatment.

P-CURVING AS A SAFEGUARD AGAINST P-HACKING IN SLA RESEARCH

It is important to be able to identify research results likely to have been arrived at by means of “p-hacking,” a common term for research and reporting practices (such as the selective reporting of results) that are biased toward finding p < α. This paper discusses and demonstrates “p-curving,” a means of checking a set of primary studies within a specific research stream for signs of p-hacking. A salient feature of p-curving is that it is based entirely on significant p-values. Because of the potential usefulness of p-curving and because it has been little used by SLA researchers, a case study illustrates the construction and analysis of a p-curve as a complement to meta-analysis. The focal p-curve in this study relates to published (quasi)experimental studies that addressed the research hypothesis that for low and middle proficiency learners L1 glosses facilitate vocabulary learning during reading better than L2 glosses do.

Impact of E-maintenance over Industrial Processes

During the course of the industrial 4.0 era, companies have been exponentially developed and have digitized almost the whole business system to stick to their performance targets and to keep or to even enlarge their market share. Maintenance function has obviously followed the trend as it’s considered one of the most important processes in every enterprise as it impacts a group of the most critical performance indicators such as: cost, reliability, availability, safety and productivity. E-maintenance emerged in early 2000 and now is a common term in maintenance literature representing the digitalized side of maintenance whereby assets are monitored and controlled over the internet. According to literature, e-maintenance has a remarkable impact on maintenance KPIs and aims at ambitious objectives like zero-downtime.

Zinc (II) and AIEgens: The “Clip Approach” for a Novel Fluorophore Family. A Review

Aggregation-induced emission (AIE) compounds display a photophysical phenomenon in which the aggregate state exhibits stronger emission than the isolated units. The common term of “AIEgens” was coined to describe compounds undergoing the AIE effect. Due to the recent interest in AIEgens, the search for novel hybrid organic–inorganic compounds with unique luminescence properties in the aggregate phase is a relevant goal. In this perspective, the abundant, inexpensive, and nontoxic d10 zinc cation offers unique opportunities for building AIE active fluorophores, sensing probes, and bioimaging tools. Considering the novelty of the topic, relevant examples collected in the last 5 years (2016–2021) through scientific production can be considered fully representative of the state-of-the-art. Starting from the simple phenomenological approach and considering different typological and chemical units and structures, we focused on zinc-based AIEgens offering synthetic novelty, research completeness, and relevant applications. A special section was devoted to Zn(II)-based AIEgens for living cell imaging as the novel technological frontier in biology and medicine.